Posted by admin on Sep 30, 2019 in |
Curcuma aromatica salisb, which belongs to the Zingiberaceae family, is a perennial herb. The rhizome of the plant consists of alkaloids, curcuminoids, flavonoids, tannins, and terpenoids which are reported to be the reasons for its various pharmacological properties. The extraction of compounds in different solvents shows that the plant contains neocurdione, curdione and germacrone as its major components. An extensive literature survey showed that the plant has anti-obesity, anti-acne, anti-cancerous, anti-tussive, anti-oxidant, larvacidal anti-inflammatory, anti-bacterial and wound healing properties. The rhizome extract of the plant is highly effective against many human pathogens as well as microorganisms causing food spoilage and foodborne diseases. The aim of this study is to review the phytochemical and pharmacological properties of Curcuma aromatica...
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Posted by admin on Aug 31, 2018 in |
Rheumatoid arthritis (RA) is a chronic inflammatory and systemic autoimmune disease, affecting people predominantly between the ages of 20-60 years with an unpredictable course. About 1% of the world’s population is afflicted by rheumatoid arthritis and is two to three times more common in women than men. This is a long-lasting disease that can affect joints in any part of the body, most commonly the hands, wrists, and knees. The popularity of medicinal plants is increasing day by day due to the side effects of allopathic medicines. Herbal medicinal plants have been used as major sources of cure of human diseases since time immemorial. Today, one-fourth of the world population depends on traditional medicine, and 80% of the population relies on indigenous herbal medicinal plants. Even today most of the people live in different developing countries depend on the plant-derived medicines for the first line of primary health care because of least or no side...
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Posted by admin on Aug 31, 2018 in |
Digitalis purpurea commonly known as foxgloves belong to the genus Digitalis, which is a member of the family Plantaginaceae. Due to their effectivity in the treatment of heart insufficiency, cardenolides from Digitalis have been used extensively worldwide. Digitalis purpurea is the most important source of cardiac glycosides or cardenolides, volatile oil, fatty matter, starch, gum, and sugars. They possessed cardiovascular, cytotoxic, anti-diabetic, antioxidant, insecticidal, immunological, hepatoprotective, neuro-protective and cardioprotective effects. This review highlights the plant profile, history, chemical constituents, chemical test, traditional uses, drug interaction and pharmacological effects of Digitalis...
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Posted by admin on Aug 31, 2018 in |
The qualitative estimation of herbal formulation Lohasava, is of principal importance to justify their adequacy in the present system of medicine. One of the key problems which are faced by the herbal drug industry is the unavailability of rigid quality control profiles for herbal materials and their formulations. Regulatory bodies have such as WHO, AYUSH, ICH, etc., had laid down the standardization and specifications parameters for various Ayurvedic preparations. The present Investigation evaluated different brands of Lohasava available in the market as per WHO and Indian Pharmacopoeial specifications. Various physicochemical parameters such as Loss on drying, total ash, sugar content, alcohol content, and microbial content were determined. The result reveals that all the preparations contain acceptable levels of alcohol (less than 12%...
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Posted by admin on Aug 31, 2018 in |
Cytotoxicity of lipopolysaccharide (LPS) as a bacteria-related compound and paraquat (PQ) as a non-bacterial toxicant on freshly isolated alveolar macrophages (AMs) was studied. At the same time, preventive, protective and therapeutic effects of quercetin (QCN) against LPS-induced and silymarin (SMN) against PQ-produced cytotoxicity as known antioxidants with potent anti-inflammatory property were also investigated. Freshly isolated rat’s AMs were exposed to low, medium and high concentrations of LPS (1, 5 and 10 µg/ml), PQ (1, 5 and 10 µg/ml), QCN (1, 5 and 10 µg/ml) and SMN (25, 50 and 100 µg/ml), separately. After that, the effective concentration of LPS/PQ along with low, medium and high concentrations of QCN/SMN in the forms of preventive, protective and therapeutic was evaluated on cell viability, lactate dehydrogenase activity (LDH), nitric oxide content and total antioxidant capacity (TAC) of alveolar macrophages. Results showed that both LPS and PQ in a concentration-dependent manner reduced the cell viability and TAC values and elevated the NO content and LDH concentration. By contrast, QCN and SMN administration alone...
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