DEVELOPMENT OF QUALITY PARAMETERS OF TALISADI CHURNA AND ITS MARKET FORMULATIONS

Talisadi Churna is a classical Ayurvedic polyherbal formulation traditionally used in cough, bronchitis, fever, dyspepsia, anaemia and cardiac disorders. The present study was carried out for pharmacognostical, physicochemical and phytochemical evaluation of standard laboratory-prepared and marketed formulations in accordance with WHO guidelines. Diagnostic microscopical features of each crude drug such as lignified fibres, stone cells, starch grains, oleo-resinous parenchyma, silicate crystals and epidermal characters were confirmed in all the formulations, ensuring its identity and authenticity. Phytochemical screening detected alkaloids, flavonoids, phenolics, tannins, carbohydrates, steroids and triterpenoids. Comparative TLC fingerprinting confirmed the presence of all crude drugs in prepared and marketed formulations. HPTLC quantification using piperine as a marker revealed highest content in P. nigrum (4.86%w/w), followed by P. longum (4.809% w/w). Among formulations, laboratory prepared contained 4.88% w/w, with comparatively lower amounts in marketed formulations. The findings provide a comprehensive standardization profile for Talisadi Churna, ensuring quality of both laboratory-prepared and marketed formulations.