Posted by admin on Jul 31, 2021 in |
A good number of medicinal and aromatic plants are used as complementary and alternative medicine in different regions of Nigeria. However, some of this valuable ethnobotanical knowledge has not been formally documented. Hence, the objective of this study was to document the ethnomedicinal plants, their preparations, and applications in managing a variety of ailments in the Oju local government area of Benue State, Nigeria. Twenty-three traditional healers (16 male and 7 female) of different ages (42–75 years) were purposively and randomly selected with the help of administrative personnel in collecting the plant species. A key informant interview guide was used to collect the data. Thirty-three plants species belonging to 26 families were collected and documented. Of the 33 species, 55% were trees, 21% shrubs, 21% herbs, and 3% climbers. Leaves were the most utilized plant part. The routes of administration are mainly internal, in which oral administration is the common one. A total of 23 different prescriptions for the individual plant and in combination were recorded for their healing...
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Posted by admin on Jul 31, 2021 in |
The discovery of drugs for Alzheimer’s disease (AD) therapy that can also permeate the blood-brain barrier (BBB) is very difficult owing to its specificity and restrictive nature. The BBB disruption or drug administration directly into the brain is not an option due to toxic effects and low diffusion of the therapeutic molecule in the brain parenchyma. A promising approach for systemic drug delivery to the central nervous system is the use of nanosized carriers. The therapeutic potential of certain nanopharmaceuticals for AD has already been demonstrated in-vivo after systemic delivery. Herbosomes have an enhanced absorption rate, producing excellent bio-availability, good penetration power. Herbosome technology is one of such systems that incorporate phospholipids into standardized active ingredients of herbal extracts, thus effectively enhancing the bioavailability of water-soluble bioactive constituents of phytomedicines such as flavonoids, phenolics and hydrophilic compounds. These phytoconstituents have been established to exhibit a variety of biological activities that have pharmacological benefits. However, poor absorption of these phytoconstituents limits their bioavailability. The poor absorption is principally due to...
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Posted by admin on Jul 31, 2021 in |
The demand for today’s chemistry is finding an efficient alternative to synthetic indicators. Acid-base titration was conducted using natural indicators in the present research work. The natural indicator is prepared from Jasminum sambac, the most commonly occurring plant. The ethanolic flower extract was used as a natural indicator. For acid-base titration, Hydrochloric acid (HCl) as strong acid and Acetic acid (CH3COOH) used as a weak acid, and Sodium hydroxide (NaOH) were chosen as a strong base. Successful results were achieved when it was examined by using standard synthetic indicators. Titration shows colour change at the point of equivalence. Thus, for acid-base titration at any dilution, natural indicators from flowers can be used. Titration with natural indicator from ethanolic flower extract of Jasminum sambac has not yet been performed by any research team. It is very simple and economical to use ethanolic flower extract of Jasminum sambac as an indicator as it provides the same outcome accuracy as that provided by the synthetic...
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Posted by admin on Jun 30, 2020 in |
Context: Dhamaso, botanically known as a Fagonia Arabica is an important plant in Ayurveda and in folklore medicine, but little is known about its pharmacognostic evaluation. Objectives: In the present investigation, the detailed pharmacognostic study of Fagonia arabica stem is carried out to lay down the standards which could be useful in future experimental studies. Materials & Methods: The present study included macroscopy, microscopy, preliminary phytochemical screening, and physicochemical evaluation. Results: Macroscopy reveals the organoleptic properties of the stem, and the microscopic study shows the presence uni-seriate to tri-seriate medullary rays and brownish matter in pith region as diagnostic characters. Water-soluble ash value is more than acid insoluble ash indicates that the acid-insoluble siliceous matter was less than that of water-soluble ash. The preliminary phytochemical investigations indicate the presence of glycosides, flavonoids, saponins, sterols, carbohydrates, amino acids,...
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Posted by admin on Jun 30, 2020 in |
The plant Bauhinia varigata is a medium-sized tree found throughout India, ascending to an altitude 1350 m in the Himalayas. It is a species of flowering plant belonging to the family Fabaceae. Kanchnar, Mountain Ebony, Rakta Kanchnar are the common name of Bauhinia varigata. The various parts of the plant like flower buds, flowers, stem, stem bark, leaves, seeds, and roots are used in various indigenous systems of medicine. For the last many years, this plant is very popular among the various ethnic groups in India for the curing of a number of diseases. Traditionally, it is used in the treatment of diarrhea, dysentery, Goiter, Tumor and Kapha- Pitta dosha disorders while flowers have Pittaghna (Pacify pitta dosha), piles, constipation, and leprosy. There are a number of phytochemicals isolated from the various part of kanchnar such as flavonoids, kaempferol, ombuin, hesperidine, triterpenecaffeate, flavonol glycosides, flavanone, stigmasteroles, octacosanol, Phenanthraquinone, protein, calcium and phosphorous, volatile oil, germacrene D, quercetin, rutin, etc. Upon medicinal and biological studies, anti-inflammatory & analgesic activity, chelation...
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