Posted by admin on Jul 11, 2017 in |
Standardization is the need of the hour in Ayurvedic system of medicine. The traditional systems of medicine are really effective but the problem with them is they lack in quality assurance. This enables us to recognise the quality of the formulation. The Central Council of Research in Ayurveda and Siddha has prescribed the preliminary guidelines for testing the quality of these formulations. It is essential to derive a protocol or develop methods for evaluation of herbal formulation to maintain uniformity between batches during production. The present work aims to standardize a poly-herbal churna called Gandharva haritaki Churna available in the market. The churna was procured and standardised for the parameters like organoleptic characters, physical characters, physiochemical properties and phytochemical screening etc. These parameters can determine the quality of the product. The results were found to be within the...
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Posted by admin on Jul 11, 2017 in |
The present study was investigated to establish the diuretic and antiurolithiatic activities of chloroform and ethanolic leaf extract of Melochia corchorifolia. The chloroform and ethanolic leaf extract were administered to experimental rats orally at a dose of 200 mg/ kg and 400 mg/kg. Furosemide (5 mg/kg) was used as reference standard for diuretic activity. The parameters measured for diuretic activity was total urine volume; urine electrolyte concentrations such as sodium, potassium, chloride, and bicarbonates. In the in-vitro antiurolithiatic activity, Calcium oxalate crystallization was induced by the addition of 0.01M sodium oxalate solutions in synthetic urine. The effect of chloroform and ethanolic leaf extract of Melochia corchorifolia (100, 200 and 500 μg/ml) was studied by time course measurement of absorbance at 620 nm for ten minutes using a spectrophotometer. Both the extracts show good in-vitro antiurolithiatic activity. In the in-vivo antiurolithiatic activity, urolithiasis was induced in male rats by administering ethylene glycol (0.75% v/v) in drinking water for 28 days, and the parameters such as oxalate, calcium, and phosphate were...
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Posted by admin on Jul 11, 2017 in |
Cadmium is a known nephrotoxic metal with other toxicities including pancytopenia. Telfairia occidentalis is a medicinal plant with antioxidant and chemoprotective properties. This study was carried out to investigate the ameliorating effects of aqueous extract of Telfairia occidentalison cadmium chloride-induced oxidative stress, renal damage and hematological alterations in rats. Twenty four (24) adult male rats were divided into 4 groups of 6 rats each. Group I received distilled water, group II, III, and IV were administered 5 mg/kg body weight CdCl2, group III; IV was treated with 200 and 400 mg/kg bw respectively of aqueous extract of Telfairia occidentalisfor 14 days while rats in group II were left untreated. Results obtained showed that administration of cadmium caused significant reduction in all the hematological parameters, reduced GSH, ascorbic acid, Superoxide dismutase (SOD), glutathione S-transferase (GST), Catalase (CAT), serum Sodium ion and bicarbonate ions as well as increase in MDA (malondialdehyde) level and serum level of potassium ion, serum urea, and creatinine. However, treatment with various doses of aqueous extract of...
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Posted by admin on Jul 11, 2017 in |
Curcuma is an important genus used in Traditional Medicine in the world. Due to similar morphological characters and same Sinhalese vernacular names of Curcuma species, adulteration or substitution takes place. The current study was conducted to understand the similarities in morphological and microscopic characters by analyzing data using multivariate test on five species available in Sri Lanka; C. albiflora, C. aromatic, C. longa, C. oligantha, and C. zedoaria. Whole plants of Curcuma species were collected in 2016, from wet and dry zones of Sri Lanka. Voucher specimens of the plants were authenticated from National Herbarium, Peradeniya, Sri Lanka. Morphological characters of five Curcuma species and microscopic characters of five Curcuma species using 5 observations of each plant were analyzed. An experiment was conducted as per WHO guidelines and other published data. Statistical tests were performed using Minitab 17. Multivariate test was used to determine the complex relationship among variables by simple correspondence analysis. Analyses examined the relationships between the 25 observations and the associations between variables in two dimensions...
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Posted by admin on Jul 11, 2017 in |
Plants contain a galaxy of phytoconstituents which accounts for their remedial worth. This plant has been used expansively for its medicinal value all over the world. Different plant parts have been used for its different pharmacological screening, including cancer therapy and leaves can be wrapped to create the “beedi” filled with tobacco which has outsold conventional cigarettes in India. Extraction of plant material with organic solvent and elucidation of pure compounds using a different technique with the different solvent system are an extremely imperative limitation. Elucidation of pentacyclic triterpenoid, ursolic acid from D. melanoxylon and molecular mechanisms has vast chances for the development of enhanced therapy for different diseases, including cancer, and clinical studies. Our extensive intention of this study is to give a general delineate on the thyme D. melanoxylon and its cancer prevention potential, diverse pharmacological action, ethnomedicinal uses, and chemical compounds. We also focus the extraction methodology, elucidation, pharmacokinetic and various clinical trials of ursolic acid chiefly obtained from D....
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