Posted by admin on Jun 30, 2018 in |
Present communication deals with the pharma-cognostical standardization on the roots of Agnimantha (Premna serratifolia L. (syn. P. integrifolia L.) belong to the family Verbenaceae. It is an important medicinal plant used in many Ayurvedic formulations. According to Ayurveda the roots and leaves are the most useful parts of the plant. It is one among the Dashamula. Macro, microscopical and physicochemical studies were carried out as per the latest Ayurvedic Pharmacopoeia of India, part-1, volume-8 protocols to establish its Pharmacognostical standards. Studies revealed the presence of abundant, simple to compound starch grains with prominent hilum in the center, cork cells filled with yellowish brown pigmented cells, starch grains in the medullary rays, abundant xylem vessels with bordered pits and tracheids with pits, prism-shaped crystals in the cortex region. Phytochemical studies showed the presence of carbohydrates, alkaloids, phenols, tannins,...
Read More
Posted by admin on Jun 30, 2018 in |
Before the advances in synthetic chemistry and discovery of antimicrobials in the 19th early to 21st centuries, plants provided the major source of medicines. Traditional knowledge is more and more an established resource for modern medical science. Ayurveda is the most ancient health care system and is practiced widely in India, Sri Lanka and other countries. This article reviews some of the past success of the natural products approach and also explores some of the reasons why it has fallen out of favour among major pharmaceutical companies and challenge in drug discovery from natural products especially higher plants. In this review we consider the past, present and future value of employing information from plants used in traditional medical practice for the discovery of new bioactive...
Read More
Posted by admin on Jun 30, 2018 in |
Curcuma albiflora Thw. is an important anti-inflammatory medicinal plant, which is used in Sri Lankan Traditional Medicine. The plant is endemic to Sri Lanka and unexplored. Therefore it is necessary to conduct a proper systematic study to establish a chemical profile of C. albiflora. Therefore, the current study was conducted GC-MS study on various extracts of C. albiflora. The whole plant parts of the plant C. albiflora were collected from June to October in the flowering season at Sabaragamuwa province, Sri Lanka. Samples were authenticated by National Herbarium, Peradeniya. Hydro-distillation by Clevenger’s apparatus and continuous extraction by Soxhlet apparatus were carried out on various solvents (petroleum ether, acetone, and methanol). GC-MS analyses were performed on various extracts (water, petroleum ether, acetone, and methanol) of C. albiflora. Retention index was calculated of each compound based on standard alkane chromatogram. The whole plant of C. albiflora essential oil consisted mainly of α-pinene (14.51%), caryophyllene oxide (9.35%), alcanfor (5.12%), aromadendrene oxide-I (4.81%), α-famesene (4.01%) and camphene (3.64%). While petroleum ether extract of...
Read More
Posted by admin on Jun 30, 2018 in |
Honey is commonly used by the indigenous population in Brazil due to its large variety of physiological properties such as ulcers and dermatitis healing. The goal of this paper is to select and to test different types of Brazilian honey to be used associated with Aloe vera as an accessible wound treatment. Three types of honey were analyzed: two produced by Tetragonisca angustula in different regions of Brazil and one honey produced by Apis mellifera scutellata, associated with both water and Aloe vera. Quantitative assays, where bacterial growth curve was analyzed by optical density, were performed to test the antimicrobial activity of the samples. From the results obtained, we observed that the three types of honey studied presented a satisfactory antimicrobial activity. The association between honey and Aloe vera, besides demonstrating better antimicrobial action than each compound itself, it demonstrated better effectiveness against Enterobacteriaceae species (E. coli and S....
Read More
Posted by admin on Jun 30, 2018 in |
Portulaca quadrifida Linn. (Portulacaceae) is commonly known as a chicken weed in English. In the traditional system, it is used to treat rheumatism and gynecological diseases, urinary tract infections, worm diseases, dysentery and dermatitis. To assess the cytotoxic potential of hydroalcoholic extract of P. quadrifida leaves using brine shrimp assay. Potassium dichromate was considered a standard reference drug. The concentrations of 10, 100, 1000 μg/ml were used in the experiment. The mature shrimps were taken, and it was treated with the extract and the standard in the respective concentrations. LC50 value was calculated for both standard and extract, and the probit analysis was made by using SPSS software. From the probit analysis, the cytotoxicity of the extract was determined by comparing it with the standard. The graph was plotted for both the standard and the extract; the extract was found to be non-...
Read More
