Posted by admin on Apr 30, 2019 in |
The present investigation was directed to assess the counter lithiasis action of ethanolic concentrates of entire plant of Bryophyllum pinnatum. Urolithiasis is an infection brought about by the nearness and impacts of uroliths (stones) or calculi or exorbitant measures of precious stones in the urinary tract. The illness is alluded to by numerous names, including cystitis, urethritis, urinary calculi, bladder stones, or kidney stone. Ethanolic concentrate of the plant of Bryophyllum pinnatum was exposed to antilithiatic action in rodents where Ethylene glycol (0.75 (v/v)) utilized as the causing lithiasis specialist. A stamped ascend in calcium, oxalates, phosphorus, and creatinine in blood serum level saw in lithiasis (100 and 200 mg/kg) displayed a portion subordinate critical enemy of lithiasis action on treatment. The concentrate portion of 300 mg/kg likewise caused fractional instruction of calcium, oxalates, phosphorus, and creatinine in blood serum level the outcomes were discovered factual irrelevant. The antilithiatic impact of ethanol separate was discovered compelling with that reference...
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Posted by admin on Apr 30, 2019 in |
Diabetes mellitus is a metabolic disorder in which blood glucose level decrease. Due to this disease, various complications are arises including retinopathy, nephropathy, cardiovascular disease, and neuropathy. Diabetes mellitus is a chronic condition includes Type 1 DM, Type 2 DM and gestatational diabetes, which occurs in pregnancy. For the management of DM various system of medicine is used, from that herbal or traditional medicine is used for many cases as a core medicine or supplementary to allopathic medicine. Frequency of occurrence of type 2 DM is high than type 1 DM. Different type of plant or herbal extract are used for management of DM includes, Ocimum sanctum, Allium stivum, Eugenia jambolana, Abelmoschus esculentus, Allium cepa, Gymnema sylvestre, Momordica charantia, Pterocarpus marsupium etc. Many plants are use as single herb extract for treatment or used in combination with other anti-diabetic plants as a poly herbal...
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Posted by admin on Apr 30, 2019 in |
Aim: The present research aims to screen anabolic activity on bone formation and bone density in normal and Teriparatide (Rh PTH biosynthetic human parathyroid hormone 1-34) induced inhibition of osteogenesis in zebrafish larval model to alleviate osteoporosis and other bone and joint disease or disorders of the Nano encapsulated essential oil isolated from the Ruta graveolens (NELVORG) Family: Rutaceae using a novel, fast, economical and genetically tractable method for screening developmental aspects of bone formation in a high throughput fashion through the visualization of embryonic and larval skeleton of zebrafish (Danio rerio) model. Method: The volatile oil (VO) was isolated from the leaves of R. graveolens and extracted VO was subjected to GC-MS Analysis. The nano-encapsulated volatile oil of R. graveolens leaves (NELVORG) was prepared by solvent displacement method, and particle size was standardized by scanning electron microscope (SEM). We implemented 3Rs (Reduction, Replacement, Refinement) ethical principle to minimize harm to the vertebrate animals. Preliminary toxicological studies were evaluated on whole embryo and larvae, showed no mortality up to...
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Posted by admin on Apr 30, 2019 in |
Molecular Beacons (MBs) are DNA hairpins that are widely used as fluorescent probes. The inherent signal transduction mechanism let them differentiate between target and non-target oligonucleotides that differ even on a single base. The stem-loop structure consists of donor and acceptor moieties conjugated to both ends thus lying nearby, which leads to FRET. On hybridization to target sequences that hairpin opens up, restoring fluorescence. MBs technology can be applied to a wide range of fields from genetic screening, biochip development, biosensor construction and even mRNA expression in living cells. Recent developments consist of modifications to improve not only the stability of MB in living cells but also lowering signal to noise...
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Posted by admin on Apr 12, 2018 in |
Anethum graveolens an important medicinal plant and one of the most widely cultivated species of the family (Umbelliferae). It is highly valued from time immemorial because of its vast medicinal properties. The present work deals with the investigation of the laxative activity of various extracts of Anethum graveolens fruits. The laxative effect was checked in using Wister strain Albino rats. All the crude extracts such as ethanol, ethyl acetate, n-butanol and petroleum ether at a dose of 200 and 400 mg/kg were tested for laxative activity, whereas agar-agar 300 mg/kg, p.o. was used as standard drugs. Among all the extract, the petroleum ether extract was found to possess the most effective laxative activity. Therefore, Anethum graveolens fruits can be a substitute for synthetic laxative drugs having adverse...
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