Posted by admin on Apr 30, 2022 in |
The “deadly nightshade” family, commonly known as “black nightshades,” it’s also used as a traditional medicine system in a country like India and China. Solanum xanthocarpum is known to contain alkaloids, steroids, glycol-alkaloids, steroid saponins, glycoproteins, that exhibit antitumor activity. This review explores the phytopharma-cological properties of Solanum xanthocarpum and summarizes its wide range of pharmacological applications to understand and integrate potential image issues as multipurpose medicines. Solanocarpidine and a phytosterol known as Carpesterol are also present. The seed oil contains Carpesterol. Diosgenin, lanosterol, sitosterol. Solasonnine, solamargine, and solasodine have been isolated from the plant. The roots and fruits are used for medicinal purposes. The herb is useful both internally as well as externally. The apoptotic effects and the amount of DNA fragmentation increased in a dose-dependent manner after the treatment with the protein. Authors believe this glycoprotein is a natural anticancer agent due to its potential to induce apoptosis in the HTC29...
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Posted by admin on Apr 30, 2022 in |
Inflammation is initiated as a healing process by the tissue in response to an injury by pathogens, irritants or cell damage. Piper attenuatum B. Ham is a rare piper species found in the tropical, sub-tropical region and mainly found in the southern part of India. A plant has constituents like alkaloids, amides, glycosides, tannins etc., which are responsible for its therapeutic efficacy. This research focuses on the use of leaves of Piper attenuatum B. Ham as anti-inflammatory agents. The phytochemical and analytical evaluation was done for ethanolic leaf extract. Various part of the plant is used for treating fever, malaria, diuretic, and cancer. Piperine is a major alkaloid found in almost all piper species & responsible for anti-inflammatory activity. In the present study, ethanolic leaf extract of Piper attenuatum B. Ham at doses 200mg/kg and 400mg/kg showed significant in-vivo anti-inflammatory activity in carrageenan-induced paw edema in rats and in-vitro anti-inflammatory activity by protein denaturation method for dose 500, 400, 300, 200 & 100...
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Posted by admin on Apr 30, 2021 in |
Objective: Plants live on a planet with days and seasons, affecting their phytoconstituents. The challenge is that availability of active principles in medicinal plants changes by seasonal fluctuations, so their dose pattern for therapeutic efficacy also get influenced. The best duration for the harvesting of specific secondary metabolites for better yield is not fixed. Seasonal impact show changes in important constituents like polyphenol, flavonoids, glycosides, alkaloids, essential oil, etc. Late summer is the best collection time for essential oil components. Winter and rainy are the best season for other secondary metabolites. Methods: The selected plant Azadirachta indica A. belongs to the alkaloidal category with having anti-diabetic activity. Plants were evaluated for pharmacognostic study, which includes macroscopic and microscopic evaluation, determining physicochemical parameters systematically. HPTLC fingerprinting for nimbin was done. The study was performed for plant material with three different seasons, and the best results were analyzed. Results and Conclusion: All the plants showed correct taxonomy with specific morphological, microscopical, and physicochemical parameters, which is helpful for the standardization of...
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Posted by admin on Apr 30, 2021 in |
Alzheimer’s syndrome/disease is known for its progressive Neuro-degenerative illness and considered pathologically by the deposition of β-amyloid peptide and senile plaques (a pathological accumulation of paired helical filament composed of abnormally formed tau protein in the hippocampus of our brain). This serves to maintain the memory deterioration. Along with that, the treatment and prevention of synthetic drugs having a long list of adverse effects. Alzheimer’s syndrome induced through aluminium trichloride (4.2 mg/kg intraperitonial) continues for 28 days. The albino Wistar rats were divided into 5 groups (n=6 in each group) then weighed for 28 days of induction of disease. Extract of dried leaves of Camellia sinensis. (200 mg/kg and 400 mg/kg) along with standard drug (Donepezil 2 mg/kg) by oral route given through (1% CMC suspension) after treatment showed a significantly decreased escape latency. Previous studies for Camellia sinensis showed that it is efficient in the prevention of deposition of senile plaques. Along with neurofibrillary tangles in the hippocampus with deficits in enhanced memory...
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Posted by admin on Apr 30, 2021 in |
Anaemia globally affects 1.62 billion peoples in the world. To treat anaemia, Hibiscus acetosella is sometimes used traditionally. This study has been conducted to evaluate the anti-anaemic effects of the aqueous leaves extract of Hibiscus acetosella, on two experimental models of anaemia. Bleeding anaemia was induced by retro-orbital puncture of 2-2.5 mL of blood during two days, while haemolyticanaemia was induced by intra-peritoneal injection of 2. 4 dinitro-phenylhydrazine (40 mg.kg bw) during 7 days. After induction, plant extract (100; 200 or 400 mg.kg bw) was daily administrated by oral route for 14 days. During experience, haematological analysis was done at the beginning, at the end of induction and every week during treatment. During haemolytic anaemia; aqueous extract significantly increased haematocrit and red blood cell with the maximum of 45% and 32% respectively at the dose of 400 mg.kg.bw; haemoglobin significantly increased in rats with a maximum of 32% at the dose of 200 mg.kg bw. In bleeding anaemia model, H. acetosella significantly increased the haematocrit as well as red...
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