Posted by admin on Dec 31, 2019 in |
Natural compounds have already contributed to the discovery of new anti-malarial drugs. Atovaquone, artemisinin and its semi-synthetic derivatives as well as clindamycin, erythromycin, azithromycin, chlortetracycline, tetracycline, oxytetracycline and doxycycline, are noteworthy examples of the varied contribution of natural products for the development of effective anti-malarial drugs, particularly valuable for the treatment of chloroquine-resistant parasites. To avoid side effects and the resistance developed by the synthetic drug natural drug preffered. However, in many cases good activity and selectivity were observed. Most importantly, several compounds containing unique structural composition have been isolated and characterized. In the present review, a number of potential anti-malarial plants explored have been brought out, and a number of leads suggested on the basis of their anti-malarial activities. Thus, it provides guidance for areas of further research on potential plant resources that could be sources of compounds with therapeutic properties for the treatment of malaria. Some of the plants were investigated for anti-malarial activities, and their efficacy, toxicity, and safety aspects still need to be...
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Posted by admin on Dec 31, 2019 in |
Herbs are used as a source of medicine in Ayurveda and also in some traditional systems of medicine as having lesser side effects and cost when compared with synthetic drugs. Plants live on a planet with days and seasons, and that affects their phytoconstituents. The availability of active principles in medicinal plants changes by seasonal fluctuations, so their dose pattern for therapeutic efficacy also gets influenced. The best duration for the harvesting of specific secondary metabolites for better yield is not fixed. Seasonal impact show changes in important constituents like polyphenol, flavonoids, glycosides, alkaloids, and essential oil. Late summer is the best collection time for essential oil components. Winter is the best season for the harvesting of secondary metabolites containing plant parts. The results of these studies may help the researcher those who are involved in exploring the isolation of valuable chemicals from the plants for the treatment of various diseases. Therefore, the current review aims to focus on the best possible season for the harvesting of pharmaceutically important...
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Posted by admin on Oct 31, 2019 in |
World major population was dependent on traditional medicines, derived from medicinal plants. Among which India plays a crucial role in health management using herbal derivatives and excipients. Majority of plants and their derivative products isolated from different parts shown to have significant therapeutic and pharmacological potentials. Various plants species have been envisaged, among which Terminalia is one of the treasuries in which all parts of this plant having therapeutic activity by isolation of different Phytocompounds in varying solvents according to polarity and nature of compounds isolated using extraction. The amount and quantity of phytochemicals present in different plants differ from one another. Among the various screened species of genus Terminalia, it was reported that around 200-250 species are widely used as traditional medicine in curing various ailments such anti-HIV reverse transcriptase, anti-diabetic, antioxidant, antifungal, anti-cancer, hepatoprotective, anti-inflammatory, anti-hepatitis and aphrodisiac effects. The aim of present study was to review its extracted phytoconstituents present in different parts along with their pharmacological benefits and usage. Which further helps emerging researchers to...
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Posted by admin on Oct 31, 2019 in |
Cannabis is one of Morocco’s top industries, and Morocco is one of the world’s top Cannabis providers, however, the growth, the development, deal, and utilization of Cannabis is especially unlawful under the present legislation. Morocco has one of the most stringent law enforcement systems, but it has not legalized, there are 3 possibilities. The first is a continuation of the present ambiguity; the second to legalize; and the third is to completely authorize the present laws, ending in elimination of the culture each of these ways would impact affect Morocco, both financially and socially The purpose of this article is to update the current regulations on the utilization of Cannabis for medical purposes in Europe and Morocco. Thus, the botanical aspect, the chemical composition of Cannabis sativa is approached. This article will not discuss the recreational use of Cannabis. The review is based on information gathered from previous reports and government...
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Posted by admin on Sep 30, 2019 in |
Infectious diseases are one of the major problems in the world. After the discovery of penicillin, many classes of the antimicrobial agent were introduced and most infectious diseases were brought under control. However, the increased use of these antimicrobial agents in clinical practice was soon followed by the emergence of antibiotic resistance. Because of multiple drug resistance and adverse effects of these antimicrobial agents on the host, there is the need to discover and develop natural antimicrobials that are safe and with better therapeutic effects. Medicinal plants have been used as an alternative source of medicine to treat infectious diseases due to their rich antimicrobial activity. These Plants contain bioactive compounds such as quinines, phytoalexins, phenols, alkaloids, flavonoids, terpenoids, steroids, tannins, glucosinolates and pathogenesis-related proteins, which exert antimicrobial activity by different mechanisms, such as destruction of the cell membrane, inhibition of protein synthesis and enzymes impregnated on the cell membrane. There are various extracts of medicinal plants with minimum inhibitory concentration against pathogenic microorganisms that are safe and effective...
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