Posted by admin on Jan 31, 2022 in |
The solid drug dosage form, especially the tablet formulations, are made with natural polymer- microcrystalline cellulose (MCC) fibers with many other inorganic agents exclusively to achieve the physical form of the tablet than to enhance the drug efficacy or lowering dosage or frequency of administration. Direct compression is effected directly or after following the procedure of wet granulation. If we explore various digestible fibers from vegetable sources and extract the fibers using the same process as that of MCC, the drug delivery and additional effect of the base can be achieved simultaneously. The review article discusses various ingredients used in tablet formulation and their possible limitations and side effects. Further, the article also elaborates on various physiological, genetic, and tissue-related thrush-holds modifications in the human body viz., tachyphylaxis, tolerance, and other changes towards various drugs, and how such modifications pose an additional challenge in the treatment. Such challenges always compel us to look for newer drug molecules where a simple change in the delivery mechanism armamentarium of the tablet...
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Posted by admin on Jan 31, 2022 in |
Natural herb Ajwain, Trachyspermum ammi (L.) Sprague is an annual herbaceous plant belonging to the highly valued medicinally important family, Apiaceae; the essential oil from the fruits are the phenols, mainly thymol, and some carvacrol. The Indian Pharmacopoeia requires Ajowan oil to contain not less than 40 percent thymol. The remainder of the oil is called ‘thymene’. Thymene, which constitutes c. 45 percent of the oil, has the following composition: p-cymene, 50-55; gterpinene, 30-35; a- and ß-pinenes, 4-5; and dipentene, 4-6%. Presence of minute ‘amounts of camphene, myrcene, and D3-carene is also reported. Kapoor is a tree of many faces as it is a giant, stately forest tree native of the wet forests of tropical and subtropical regions of Asia. The species Camphora refer to camphor, an important chemical constituent present in the oil found in tree tissues. The botanical name is derived from the Greek language. It is derived from the word ‘kinnamomon’ which means spice. This herb is recorded in Sanskrit also. This is also used by...
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Posted by admin on Dec 31, 2021 in |
The Plant Costus igneus is a member of the Costaceae family. The family Costaceae has about 200 species, of which genus Costus being largest comprises about 104 species. Costus igneus is indigenous to South-East Asia. Costus igneus is often called as ‘Insulin plant’ as it helps to elevate the insulin levels in the body and hence, works as a hypoglycemic agent. The phytochemical analysis of the leaves of Costus igneus revealed that it has higher compositions of iron, protein, and antioxidant substances such as ascorbic acid, α-tocopherol, β-carotene, terpenoids, steroids, and flavonoids. The traditional utilization of this plant included promoting healthy life and age, treating rashes, asthma, and bronchitis, reducing fever and eliminating intestinal worms. This article aims to review the pharmacognostic study of Costus igneus and explore its pharmacological activities such as antidiabetic activity, antiproliferative activity, antimicrobial activity, antiurolithiatic activity, its effects on learning and memory, antioxidant activity, hepatoprotective activity,...
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Posted by admin on Dec 31, 2021 in |
Coronavirus illness 2019 (COVID 19) has wreaked havoc worldwide and resulted in a high number of deaths. One of the key reasons for the coronavirus illness (COVID 19) having such a large impact on society is its unanticipated spread, while it has prevented adequate preparation. While it will take decades to develop a vaccine, immediate interventions are required to prevent COVID 19 related mortality. We have discovered that the immune system is crucial in reducing the severity of COVID 19 and that by modulating it, it’s possible to save people’s lives. Nowadays, post-Covid diseases Mucormycosis also spreads in humans, which is very dangerous to humans financially and mentally. Because any authority has approved no specific treatments or vaccines, there is a need for an alternative to improve population immunity. Antioxidants derived from natural resources can be used as a nutraceutical to boost immunity. The nutraceuticals are non-toxic and can be used by people of all ages. There is a chance that if they include nutraceuticals in their diet regularly,...
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Posted by admin on Nov 30, 2021 in |
Before discovering synthetic drugs, peoples were dependent completely on the herbal medicinal plants for the prevention and treatment of various diseases or ailments. This is the era where a large number of synthetic drugs have been discovered for the treatment of various diseases and better health care for people suffering from various diseases. However, herbal drugs are still the choice for treating many diseases. They are preferred over synthetic drugs as they are pharmacologically very active and have no side effects or low side effects when used for the treatment of diseases. B. serrata is one of the medicinal plants amongst many other plants used traditionally to treat various ailments or diseases. The medicinal plant has a long-range of reported pharmacological activities viz. anti-inflammatory activity, anti-arthritic activity, anti-rheumatic, analgesic activity, antimicrobial activity anti-oxidant activity, anticancer activity, antitumor activity, anti-asthmatic activity, anti-diarrhoeal activity, immunomodulatory activity, hypo-lipidaemic and hepatoprotective activity, anti-complementary activity, antifungal, anti-convulsant activity, anti-obesity, cardiotonic activity and anti-ulcer activity. The Oleo-gum-resin of the plant B. serrata is traditionally used...
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