Posted by admin on May 1, 2014 in |
Aims: Analgesic and anti-inflammatory effects of Vitex negundo leaves extract (VNE) were evaluated in the animal models. The VNE was evaluated for the phytochemical analysis. Settings and Design: Factorial design was used for the experimental models. Methods and Material: The analgesic effects at graded doses of VNE (40-320 mg/kg, p.o.) were evaluated in mice against acetic acid-induced writhing (chemically induced pain) and hot-plate method (thermally induced pain). The analgesia produced by VNE was compared with the standard analgesics diclofenac sodium (DIS, 5 mg/kg, p.o.) and pentazocine (PTZ, 5 mg/kg, p.o.). Acute anti-inflammatory activity of VNE was also analyzed using carrageenan-induced rat paw edema model at the doses 40, 80 and 160 mg/kg i.p., using diclofenac sodium (5 mg/kg, i.p.) as standard. Statistical Analysis Used: ANOVA was applied followed my Tukey’s post hoc test for comparison between the group’s Results: In comparison to control group VNE showed highly significant, dose-dependent analgesic activity against chemically as well as thermally induced pain models (P<0.05). In comparison to control, VNE at the employed...
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Posted by admin on May 1, 2014 in |
Launea cornuta Asteraceae is widely used among African communities for its medicinal and nutritional values and livestock fodder. Traditionally, it is used by Kenyan communities to manage diabetes mellitus, syphilis, and stomachache, among many other diseases. The current study profiled the organic chemical compounds in the ethyl acetate extracts of L. cornuta. Chemical compounds were identified using gas chromatography coupled to a mass spectrometer. The compounds chromatograms were deconvoluted and identified by matching with NIST 11 mass spectral database. The following chemical compounds were identified; isoquinoline alkaloids, terpenoids, and phytosterols, among others. The presence of diverse chemical compounds supports the medicinal and nutritional uses of L. cornuta among African...
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Posted by admin on Apr 1, 2014 in |
The poisonous and medicinal plants are found in a natural ecosystem. The Arisaema murrayi (Hook) is an herb which is highly poisonous. It is found in the hilly region of Mumbai area. Livestock, cattle and human beings do not consume fruits and tubers of the plant, so the forensic study of this plant is carried out. Aqueous extracts of tuber 2%, 4% and 6% feed orally to Swiss albino mice. Present investigation study includes the histopathology, phyto-chemistry and quantitative microscopy. It is observed that liver, intestine, and kidney were severally damaged by using the Arisaema murrayi (Hook) plant parts. The forensic study proved that these organs were damaged by the poison of Arisaema murrayi (Hook) plant of the...
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Posted by admin on Apr 1, 2014 in |
World Health Organization appreciated the importance of medicinal plants for public health care in developing nations. The tribal region of Ghoti Taluka-Igatpuri, district-Nashik has various medicinal plant species to cure the ailments. This medicinal plant species are found in the Kokani region of Ghoti and Igatpuri. The pharmacognostic study of these medicinal plants used in ghoti tribal region can help to discover new drugs to cure various ailments provided the data given is scientifically evaluated. The present study highlights the pharmacognostical as well as phytochemical studies including parameters such as macroscopic, microscopic characters, physical evaluation and preliminary phytochemical studies of some medicinal plants used in Ghoti region of Nashik district. These observations will help in the pharmacognostical identification and standardization of the drug in the crude form and also distinguish the drug from its...
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Posted by admin on Apr 1, 2014 in |
Aim of this study was to determine the presence of phytochemical components in Saussurea obvallata and Pittosporum eriocarpum, two endangered medicinal plant species of Uttarakhand. Phytochemicals are non-nutritive plant chemicals that have protective or disease preventive properties. These components are produced by plants to protect themselves, but recent researches demonstrate that they can also protect humans against diseases. Our research shows the presence of active components in Brahma kamal and Agni extract with different solvents like methanol, ethanol, chloroform, and distilled water. Traditionally these herbs had been used for the treatment of various disorders like paralysis of limbs, cerebral ischemia, narcotic, expectorant, bronchitis, urinary tract problems, cough, etc. Our results indicated the presence of active components like alkaloids, flavonoids, terpenoids, etc. These components are responsible for the modulation in different disorders like Alzheimer, stroke, and epilepsy, etc. Our research team is carrying out a detailed investigation of components and its role in different...
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