Posted by admin on Sep 2, 2015 in |
The present study was investigated to determine the possible phytochemical components from the solvents such as hexane, ethyl acetate and ethanolic extract of Aerva lanata. Among the phytochemical screening of these extracts, ethanolic extract showed that the whole plant was rich in carbohydrate, tannin, flavonoids, quinones, cardiac glycosides, phenols, and coumarins. Further, the study was extended by analyzing the antioxidant potential using DPPH method. Among all the extracts ethanolic extract showed better antioxidant activity at the concentration of 75 µg/ml when compared to other...
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Posted by admin on Sep 2, 2015 in |
The aim of the present study is the phytochemical screening of gum of Curcuma amada (Mango ginger). Natural gums are economic, easily available and found useful as a tablet binder. The phytochemical properties of a gum obtained from the rhizomes of Curcuma amada were characterized by various test including a test for steroids, tannins, flavonoids, amino acids, carbohydrates, and glycosides. All of the test except for carbohydrates were negative confirms the presence of...
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Posted by admin on Sep 2, 2015 in |
Plants have been used for centuries as a remedy for human diseases because they contain phytochemical components of therapeutic values. Hexane, ethyl acetate and ethanolic extract of Premna latifolia were investigated for phytochemical constituent and antioxidant activity. The phytochemical constituent was investigated using standard chemical methods. Further, the study was extended by analyzing the antioxidant potential using DPPH method. The results showed that ethanolic extract showed a significant number of phytoconstituents and better radical scavenging activity at the concentration of 75...
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Posted by admin on Sep 2, 2015 in |
Dandruff is a common disorder affecting the scalp. Malassezia furfur, the lipophilic dimorphic yeast-like fungus is the main causative agent of dandruff. In recent years plant-based products are widely used as the therapeutic weapon to cure human disorders. The plant Garcinia indica (Kokam) belonging to family Clusiaceae native to India is one of such plants which has shown many therapeutic uses. One part of the present study shows that the optimum conditions for the growth of Malassezia furfur were on sabouraud’s dextrose liquid medium supplemented with corn oil at 30 °C with pH ranging between 8 and 9 and the other part emphasizes on the screening of M. furfur against fractions separated from fruit rinds of G. indica. Out of three screened fractions (Methanolic extract, water fraction and ethyl acetate fraction), ethyl acetate fraction showed a good zone of inhibition 18.2 ± 0.3 mm and 22.6 ± 1.22 mm at 75 and 100% concentration...
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Posted by admin on Sep 2, 2015 in |
Objective: a Transdermal patch is a promising approach that allows continuous input of drugs with short biological half-lives. 18 β-Glycyrrhizic acid (GA) is chemically pentacyclic triterpenoid which possesses powerful anti-inflammatory action. The present study was designed to formulate GA reservoir-type transdermal patches using piperine as bioenhancer. Method: Transdermal Patch of GA was prepared using heat seal technique using 23 factorial design allowing for independent variables like penetration enhancers, formulation matrix and rate controlling membranes. The GA patches were evaluated for in-vitro and ex-vivo drug permeation through cellophane membrane and rat skin respectively. The biological evaluation regarding skin irritation study and the anti-inflammatory effect of GA patches on rat paw edema were tested and compared with standard Aceclofenac patch. Result: The reservoir-type patch of F4 formulation, containing 5% menthol as a permeation enhancer, 42% ethanol, 2% carpool 934 gel bases (50 g) with 0.5% piperine provided an improved sustained release of phytopharmaceuticals through transdermal administration. The anti-inflammatory action F4 formulation showed no skin irritation with significant inhibition of rat paw...
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