Posted by admin on Mar 31, 2022 in |
Essential oils are largely employed for their therapeutic properties, and marketed extensively in the pharmaceutical and cosmetic industry. Geranium oil is a floral substitute for rose essential oil with its pungent rose-like odor and is one of the most valuable essential oils. Favorable quality properties make the geranium essential oil exigible for food industry applications. Our study aimed to assess the purity and quality of geranium oil available from various commercial producers. The gas chromatography-mass spectrometry (GC-MS) technique was used to detect and quantify the volatile constituents of geranium essential oil. 40 (fourty) volatile compounds were determined by the GC-MS method. The most abundant compounds were determined as geraniol (27.98%), citronellol (20.71%), isomenthone (6.57%), geranyl formate (6.52%) and linalool...
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Posted by admin on Mar 31, 2022 in |
Medicinal plants have been estimated as the richest holdings of traditional medicines and from these plants, many types of modern medicines were developed. Coscinium fenestratum (Gaertn.) Colebr. belongs to the family Menispermaceae and is considered a critically endangered medicinal plant. Traditionally it is used for antimicrobial agents, diabetes mellitus, cancer, and arthritis. In this study in-vitro pharmacological activities of leaf and stem extracts of C. fenestratum were evaluated. The solvent extracts were screened for antimicrobial activity against some clinically isolated bacterial and fungal cultures using the disc diffusion method. The antioxidant activity of extracts were tested by 2,2-diphenyl-1-picrylhydrazyl (DPPH) method. The acetone extract of stem showed potential antimicrobial activity than other extracts. All the pathogens were inhibited at very low concentration, very specific Klepsiella pneumoniae was inhibited at 0.156mg/mL and Phialophora verrucosa was inhibited at 0.078mg/mL of the stem extract. The methanol extracts of stem showed the highest antioxidant activity of 99.59%. followed by stem extracts of ethyl acetate (99.02%), acetone (98.79%), and petroleum ether(90.55%) were showed. Hence, the...
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Posted by admin on Feb 28, 2022 in |
Traditional knowledge and ethnobotanical use of plants have been widely acknowledged worldwide. The cicatrizing properties of extracts obtained from this plant have been scientifically studied, attributing the main biological activity to its tannin and flavonoid content. The recent commercialization of the plant drug Gynura nepalensis. requires Pharma-cognostical and Pharmacological information to develop quality-control methods for raw materials and extracts produced with the plant drug. Macro and micro morphological parameters were established to authenticate the genuine drug that allowed detection of adulterants usually found in commercial samples of this plant material. All the parameters were studied according to WHO guidelines and Indian Pharmacopoeia. These morphological characteristics can be used for rapid identification of the drug and are particularly useful in the case of powdered materials and physicochemical parameters. TLC profiling of plant extracts gives an idea about the presence of various phytochemicals. Pharmacological activity of Gynura nepalensis ethanolic leaf extracts were analyzed for total phenolic and flavonoid contents along with the antioxidant, antimicrobial and anti-inflammatory activity. The result of the...
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Posted by admin on Feb 28, 2022 in |
Sphaeranthus indicus Linn (Asteraceae) is a popular and very useful plant used in the Indian system of medicine. It is usually found in damp areas, plains, and weeds in the rice fields. In the Ayurvedic system of medicine, the plant as a whole plant or its different parts like leaf, stem, bark, root, flower, and seed is widely used for curing many diseases. The plant is enriched with secondary metabolites such as eudesmanolides, sesquiterpenoids, sesquiterpene lactones, sesquiterpene acids, flavone glycosides, flavonoid C‑glycosides, isoflavone glycoside, sterols, sterol glycoside, alkaloid, peptide alkaloids, amino acids, and sugars. The essential oil has been isolated from flowers and whole plants. In this present study, various methods are carried out to evaluate the pharmacognostic parameters of crude drug and aqeous extract of aerial part of the plant, which may form the basis for the further use of the plant and for the evaluation of its various pharmacological activities. The physicochemical evaluation confirms the quality and purity of the crude drug. Aqeous extract of Sphaeranthus indicus...
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Posted by admin on Jan 31, 2022 in |
Blighia sapida a tropical evergreen plant with a dense crown, is commonly called ackee apple. Traditionally, the stem backs and leaves of the plant are used in the treatment of high fever, strokes, malaria, headache and some eye ailments. This study examined the antiplasmodial activity of Blighia sapida leaf extracts in comparison with the standard antimalarial drug Artemether-Lumefantrine combination, with a view to determining the changes in the parasitemia level in mice infected with Plasmodium berghei. The results showed a significant decrease in parasitemia level over six days period for mice treated with Artemether-Lumefantrine, ethanolic, and aqueous leaf extracts of B. sapida, whereas the controls showed a continuous increase. The parasitemia level was significantly reduced (P<0.05) in mice treated with 6.0mg/kg body weight of Artemether-Lumefantrine with 88% suppression; those treated with the ethanolic leaf extract at 50mg/kg and 30mg/kg body weight had parasitemia suppressed by 59% and 43.67% respectively. Parasitaemia count in mice treated with 50mg/kg and 30mg/kg body weight of aqueous leaf extract of B. sapida was suppressed...
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