Posted by admin on Jan 31, 2025 in |
Pharmacognostic study is important in laying down diagnostic parameters for standardization and authentication of plant materials in their fresh, dried or powdered state. Pharmacognostic study serves as a tool to identify adulterants and prevent substitution. Authentic plant material serves as raw material for herbal drug industry and local markets where people prefer folk medicine. Impatiens walleriana (Family – Balsaminaceae) is a folk medicine. Pharmacognostic studies on Impatiens walleriana species are not reported and our findings shall contribute to proper authentication of the plant material and also resolve the complexity associated with species having same common names as other species in the same genera. In the present study various parameters organoleptic, chemomicroscopic, macroscopic and microscopic characteristics have been studied in addition to fluorescence, physical and photochemical analysis. This study therefore generates resourceful data helping to identify Impatiens walleriana and guide researchers to explore therapeutic worthiness of this...
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Posted by admin on Jan 31, 2025 in |
To evaluate the Pharmacognostic properties, phytochemical screening, anthelmintic and anti-oxidant potential of the leaves of Euphorbia Hirta Linn. Microscopic and macroscopic characteristics of fresh and dried leaf samples were analysed. serial exhaustive extraction was done with various of solvents: Aqueous, Methanol, using Soxhlet apparatus. Physicochemical parameters such as moisture content, extractive values, ash content of leaf powder were also determined. The results revealed that the leaves extracts contain carbohydrates, alkaloids, steroids, Saponins, terpenoid, flavonoids etc., The results of anthelmintic study indicated that the methanolic and aqueous extracts significantly exhibited paralysis (P<0.01) in worms in lower doses (5, 10 and 15 mg/ml) and also caused death of worms especially at higher concentration of 15mg/ml, as compared to standard drug. These studies may be helpful for identification of Euphorbia Hirta Linn plant. This phytochemical may be responsible for the therapeutic activity of the plant. Further it useful for...
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Posted by admin on Dec 31, 2024 in |
Context: Obsessive-Compulsive disorder (OCD) is one of the most common neurological illness worldwide. Marble burying behavior in murine models is a unique and precise model for the assessment of anti-OCD like action of the tested drug. Lagenaria siceraria (Molina) Standley (LS), popularly known as “bottle gourd”, is a potent indigenous vegetable plant with high therapeutic value. Objective: The aim of this study was to evaluate the anti-OCD (anti-compulsive) effects of the methanolic extract of LS fruits (MLSF) and the phytosterol rich Chloroform fraction of methanolic extract of LS fruits (CFMLS) using the marble-burying test in mice. Materials and Methods: The screening of anti-OCD action was carried out on Swiss Albino mice. Moreover LC-MS/MS analysis was carried out for the isolation and identification of the bioactive phytoconstituents responsible for the anti-OCD like effect of CFMLS. Results and Conclusions: MLSF and CFMLS, at doses of 100, 200, and 400 mg/kg, p.o., decreased the total number of buried marbles in dose dependent manner. At dose of 400 mg/ kg, CFMLS exhibited the...
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Posted by admin on Dec 31, 2024 in |
Cynometra ananta belongs to the Fabaceae family and is a source of biologically active secondary metabolites. In West Africa, C. ananta is renowned for its empirical application against a range of illnesses. The phytochemical composition, total phenolic and flavonoid levels, and in-vitro antioxidant activity of extracts made from C. ananta trunk bark were all examined in this work. TLC was used to detect phenolic compounds and total flavonoids ; spectrophotometric techniques were used to quantify the total phenolic and flavonoid contents; and the DPPH test was used to measure the antioxidant activity of extracts from maceration and sonication. Sonication produced the greatest levels of total flavonoid (14 ±0.7 µg EQ/mg of dry matter) and phenolic (482 ± 4.8 µg GAE/mg of dry matter) contents. Moreover, with a 92% trapping rate, sonication displayed the highest DPPH activity. C. ananta trunk bark is a significant source of phenolic compounds and flavonoids. Trunk bark has demonstrated therapeutic benefits in conventional settings, making it a promising candidate for alternative...
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Posted by admin on Dec 31, 2024 in |
This study explores the phytochemical composition and antimicrobial potential of Euphorbia hirta, a medicinal plant known for its therapeutic properties. Phytochemical screening of its aerial parts revealed the presence of bioactive compounds such as alkaloids, flavonoids, saponins, terpenoids, steroids, and sterols. Methanol extracts were evaluated for antimicrobial activity using the agar cup-plate diffusion method, demonstrating significant inhibitory effects against Escherichia coli. These findings highlight the plant’s natural antimicrobial properties, suggesting its potential as a valuable resource for addressing bacterial infections. Our findings suggest that Euphorbia hirta holds promise as a natural antimicrobial agent and Isolated Flavonoid from E. hirta Extracts shows maximum antimicrobial activity as compared with the whole extract of Euphorbia hirta. The study underscores the importance of Euphorbia hirta in the development of herbal-based therapeutics. Future research will focus on isolating and characterizing the active compounds responsible for its antimicrobial effects. Understanding the mechanisms of action of these compounds could lead to the creation of novel, plant-derived antibacterial agents, offering an alternative to conventional antibiotics in combating...
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