Posted by admin on Jul 29, 2016 in |
To evaluate the possible antifertility effect of 50% ethanolic extract of C. bonducella seeds in male rats. Adult, healthy, male Wistar rats were randomly selected and divided into three groups each having 7 rats. Group, I rats were treated with vehicle only and served as control. While group II and Group III rats were orally treated with C. bonducella extract at 200 mg and 400 mg/kg body weight/day, respectively for 60 days. The result of the present study indicated that there was a significant decrease in the relative weights of testes and accessory sex glands in treated rats. The density, motility, and viability of spermatozoa obtained from cauda epididymis were significantly (P<0.01 at 200 mg and P<0.001 at 400 mg) diminished in both treated groups as compared to control group. The serum testosterone level also showed significant (P<0.05 at 200 mg and P<0.01 at 400 mg) decline. The fertility rate and litter size decreased significantly in extract treated rats. Extract treatment also induced alteration in the biochemical milieu of...
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Posted by admin on Jul 29, 2016 in |
Prophet Mohammed calls Nigella sativa seed as a medicine of blessings. Nigella sativa is an herbaceous plant and cultivated in the Middle East, South East Asia and some part of Europe. Nigella sativa seed has been in use in the Middle East, South East Asia and some part of Europe over 2000 years. Until date lot of research, studies are conducted to prove the therapeutic utility of Nigella sativa seeds. In these various studies, Nigella sativa seeds and its derivative showed therapeutic activity against allergy, cough, and diabetes, different types of cancer and skin infections. It is one of the widely used spices in the Middle East, South East Asia and some part of the Europe Nigella sativa seed is intensively studied for its chemical composition. It is reported to contain Thymoquinone, Nigellimine-N-oxide, Nigellicine, Nigellidine, Nigellone, Dithymoquinone, Thymohydroquinone, Thymol, Arvacrol, 6-methoxy-coumarin, 7-hydroxycoumarin, Oxy-coumarin, Alpha-hedrin, Steryl-glucoside, Tannins, Flavinoids, Essential fatty acids, Essential amino acids, Ascorbic Acid, Iron and Calcium. The presence of these natural actives makes Nigella sativa seed as...
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Posted by admin on Jul 29, 2016 in |
Several reports are available for Rhododendron arboreum which is limited to its subspecies nilagiricum. The present study intended to examine the bioactive compounds and the antimicrobial activity of leaf extracts of R. arboreum Sm spp. nilagiricum (Zenker) Tagg against medically important four bacterial (Streptococcus pyogene, Staphylococcus aureus, Escherichia coli, Klebsiella pneumonia) and two fungal (Candida albicans and Trichoderma viride) strains. Agar well diffusion method is applied to assess the antimicrobial activity of the aqueous and methanol extracts of the plant sample. Various fractions of aqueous, ethanol, methanol and chloroform extracts confirmed the presence of alkaloids, phenols, flavonoids, tannins, saponins, terpenoids, steroids, carbohydrates, glycosides, amino acids, and proteins. The methanol extract of leaf revealed a promising antibacterial and antifungal activity against S. aureus and T. viride respectively. This study shows a broad and great therapeutic potential of the leaf extract. However further studies are necessary for this potent leaf extracts to evaluate the other parameters of antimicrobial...
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Posted by admin on Jul 29, 2016 in |
The present investigation deals with the in-vivo and in-vitro mast cell stabilizing the activity of fruits of Terminalia chebula ethyl acetate and methanol extracts at 500 mg/kg body weight. In egg albumin induced degranulation studies, Kitotifen as a standard was found to inhibit degranulation to an extent of 80.12%, where as ethyl acetate and methanolic extracts inhibited degranulation to 58.98% and 44.56% respectively similarly in compound 48/80 induced mast cell degranulation in rats ethyl acetate and methanol extracts of Terminalia chebula and standard Kitotifen showed the following percentage inhibition of degranulation of mast cell 40.28%, 51.19% and 75.12 respectively. In in-vivo study ethyl acetate and methanolic extracts at the dose of 500 mg/kg bodyweight inhibited degranulation of mast cell to the extent of 46.5 % and 37.33%...
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Posted by admin on Jun 30, 2016 in |
The stem of Spermadictyon suaveolens Roxb. (Rubiaceae) was evaluated for its pharmacognostic characteristics. The stem was assessed for its macroscopic, organoleptic, microscopic and phytochemical characters. The macroscopic study revealed variation in color of the stem when fresh and dried. The macroscopic evaluation was studied with parameters viz. color, odor, shape, and surface in fresh and dry condition. Quantitative microscopical data of wood elements as well as stomatal index studied through standard procedures. Total ash, acid insoluble ash, percentage extractives and fluorescence analysis in addition tannin, flavonoid, alkaloid, saponin in the alcoholic extract of stem powder recorded during an investigation. The quantitative estimation of protein, carbohydrate and oil was carried out by different scientific denoted methods. In the propagation study through the stem, cutting showed maximum percent sprouting in the treatment IAA 100 ppm (65%) and maximum percent survival in the treatment IAA 100 ppm (60%) followed by IAA 50 ppm (42%). Antioxidant assay by using Superoxide Dismutase showed positive results 96.7% in dark...
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