Posted by admin on May 17, 2016 in |
The study is aimed at the development of physicochemical parameters and to investigate the active principle present in Chlorophytum borvilianum and Sapindus mukorrossai. The present work embodies the investigations carried out to establish methods for quality control of drugs as per WHO guidelines: complete botanical evaluation which comprises of macroscopy, quantitative microscopy, powder microscopy, physicochemical parameters like loss on drying, extractive values, saponification value, total ash values, acid insoluble ash value, water-soluble ash value, pH value, loss on drying, bulk density and fluorescence analysis of powdered drug to investigate the phytochemicals present in the extracts in the preliminary...
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Posted by admin on May 17, 2016 in |
The aim of the present study, synthesis of new compounds of 4-methyl coumarin derivatives, from starting material (7-dihydroxy-4-methyl coumarin). A variety of chalcones derivative have been synthesized, and the proposed structures were confirmed by physical properties like UV –Visible, FT-IR and ¹ H NMR, Chem Bio Draw was used to evaluated the geometry optimization and total energies as well as dipole moment for all prepared...
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Posted by admin on Apr 23, 2016 in |
The present study was aimed to find out the antimicrobial potential of acetone extract of Acacia concinna leaf against five different bacterial strains at 100 and 200mg/ml concentrations. The disc diffusion assay was performed to access the antimicrobial potential of the extract. The agar plate containing a bacterial culture was divided into 4 zones, and each zone was independently impregnated with four sterile filter paper discs (6 mm in diameter) containing (10 µl of each concentration) distill water (Negative control), ampicillin (Positive control); Acacia concinna leaf extract (100 mg/ml and 200 mg/ml as test). Zone of inhibition and MIC (minimum inhibitory concentration) for test drug was evaluated to access the antimicrobial potency. The phytochemical analysis shows the presence of alkaloids, tannins, and glycosides that might be responsible for the aimed biological activities. Out of five bacterial strains, the test drug exhibit zone of inhibition against Mycobacterium smegmatis and Bacillus subtilis in a concentration-dependent manner. Minimum inhibitory concentration (MIC) of test drug against Mycobacterium smegmatis and Bacillus subtilis, was found...
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Posted by admin on Apr 23, 2016 in |
To access the quality of drug the standardization is very critical. As per WHO guidelines, 80% of the peoples have relied on traditional medicine in a rising nation. Most of the conventional system is valuable but a lack of standardization. The parameters studied are physicochemical parameters, phytochemical parameters & qualitative chemical tests. These values will help to obtain the batch to batch variation in traditional preparation of Mehari Choorna which is used to treat diabetes mellitus. We calculated and discussed extractive values, moisture content and ash value. The scientific method for its quality and safety evaluation is not yet to be documented. Hence in the current work, an attempt has been made to evaluate the quality parameters to be used for its preparation and...
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Posted by admin on Apr 23, 2016 in |
Over-harvesting of many traditional medicinal plants has become a threat to the country’s species diversity and has resulted in the endangerment of certain medicinal plant species. Shortly, many plant species may be unavailable for the use of industry due to over-exploitation. The present study outlines the concept of plant part substitution. The studies were carried out in Ailanthus excelsa to evaluate the possibilities of using small branches in place of stem bark which will help sustainable utilization. Stem bark and small branches of Ailanthus excelsa are compared by the physicochemical analysis, phytochemical analysis, total phenolic contents, total flavonoid contents and High-Performance Thin Layer Chromatography (HPTLC). Phytochemical analysis and HPTLC of n-hexane, ethyl acetate, and ethanol extracts showed many similarities which suggest that small branches may have nearly similar active potency like stem bark and may provide the base for further study to use small branches as a substitute of stem bark of Ailanthus excelsa. The study will be helpful in identification and quality control of Ailanthus excelsa and can...
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