PHYTOCHEMICAL ANALYSIS AND ANTITUBERCULAR ACTIVITY OF CENTRATHERUM ANTHELMINTICM SEED EXTRACTAbstract
About 4 extracts (hexane, acetone, ethanol, and methanol extraction) from the seeds of Centratherum anthelminticum was extracted. Gas Chromatography-Mass Spectroscopy characterized ethanol extract. Seven constituents from 9 peaks were identified. 2-Oxo-pentanoic acid and hexadecanoic acid are as the major constituents, and the minor constituents like Henicosanoic acid, 26-Phenoxy-hexacosanoic methanoate, Hexadecanoic acid methyl ester, dotriacontanoic acid ethyl ester, nonadec-3-ene, icosa-2,5, diene, and tetratriacontane were identified. The antimicrobial activity of the different extract was tested against human and plant pathogenic bacteria. Ethanol extract showed a significant role in inhibiting almost all tested pathogenic organisms and antitubercular activities at various concentration.
B. K. Mehta, K. N. Kumar *, D. Mehta and B. S. Gupta
Laboratory of Natural products, School of Studies in Chemistry and Biochemistry, Vikram University, Ujjain, Madhya Pradesh, India.
17 April 2016
24 June 2016
28 June 2016
30 June 2016