Posted by admin on Jul 13, 2015 in |
In the present study, an attempt was made to evaluate the changes in testis protein and metabolic enzyme activities induced by epichlorohydrin (ECH), twenty-four albino male rats were divided randomly into four groups of six rats each. One group was left untreated as controls, and the other three groups were administered, respectively, for twelve consecutive weeks, (2) 50 mg of ECH /kg/b.wt, (3) 75 mg of ECH /kg/b.wt and (4) 100 mg of ECH /kg/b.wt. In comparison with the control group, the doses of ECH (75 mg/kg/b.wt and 100 mg/kg/b.wt) resulted in lower protein levels and higher lactate dehydrogenase (LDH) activities in the testis of male rats than in control rats. The activity of gamma-glutamyl transpeptidase (γ-GT) decreased significantly at the doses of ECH (75 mg/kg/b.wt and 100 mg/kg/ b.wt) group than in the ECH (50 mg/kg/b.wt) and control group. However, a significant reduction in the activities of Na+/K+– , Mg2+-and Ca2+-ATPases in the (75 mg/kg/b.wt and 100 mg/kg/b.wt) ECH treated animals than control rats. Therefore, these changes in...
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Posted by admin on Jul 13, 2015 in |
In Ethiopian folk medicine, aqueous decoction of the leaves of Salvia schimperi is used for treatments of various ailments including diarrhea, however, to date, there appear to have been no reports on the phytochemistry, the antidiarrhoeal and the antimicrobial activity of the plant. In this study, the hydroalcoholic extract of the leaves of S. schimperi was evaluated for its antidiarrheal and antibacterial activities against castor oil induced diarrhea in mice and six clinically isolated enteric bacterial pathogens using standard agar diffusion methods, respectively. The minimum inhibitory concentrations (MIC) of the extracts were also determined using the microdilution method. The extract exerted significant and dose-related antidiarrhoeal activity when compared to the control and the standard drug, loperamide. The extract displayed highest antidiarrhoeal activity at a dose of 400 mg/kg which is comparable with that of the standard drug loperamide. The extract also showed moderate antibacterial effects against most of the test microorganisms except S. typhimurium. Phytochemical analysis of the extract revealed the presence of polyphenolic compounds such as flavonoids and...
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Posted by admin on Jun 3, 2015 in |
Butea monosperma (Family: Fabaceae). This is a moderate sized deciduous tree which is widely distributed throughout India, Burma and Ceylon, popularly known as ‘dhak’ or ‘palas,’ commonly known as ‘Flame of the forest’. The family Fabaceae compromises of 630 genera and 18,000 species. It finds use both medicinally and commercially with each part of the plant having utility. This plant species has been found to display a wide variety of biological activities. The plant is traditionally reported to possess astringent, bitter, alternative, aphrodisiac, anthelmintic, antibacterial and anti-asthmatic properties. Bark yield red juice known as ‘Butea gum’ or ‘Bengal kino’. It’s reported pharmacological properties include anthelmintic, anti-conceptive, anticonvulsive, antidiabetic, antidiarrhoeal, antiestrogenic and antifertility, antimicrobial, antifungal, antibacterial, antistress, chemopreventive, haemagglutinating, hepatoprotective, radical scavenging, thyroid inhibitory, antiperoxidative and hypoglycemic effects and wound healing activities. It is a powerful astringent and is given in many forms of chronic diarrhoea. Seeds have anthelmintic property, especially for roundworms and tapeworms. Flowers yield a brilliant yellow coloring matter due to the presence of chalcones. Such herbal...
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Posted by admin on Jun 3, 2015 in |
Four commercial normal hair shampoos produced by four famous Iranian companies were chosen for evaluating their characteristics based on scientifically measurable properties and were compared with our new developed formulation. Selection of the evaluation parameters of shampoo is a challenging test, because of the multitude of both subjective and instrumental test methodologies available for this purpose. The following characteristics were tested: physical appearance/visual inspection evaluation, stability, pH, foam quality, ability to reduce the surface tension, ash value, wetting agent and viscosity. The results of tests given much information about quality and characteristics and sensorial attributes related with famous Iranian market shampoos, so that they fit the demands and the needs of Iranian consumers. Also, a newly developed formulation for normal hair shampoo was introduced with high foaming, good wetting ability, detergency power and so...
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Posted by admin on Jun 3, 2015 in |
The present study was investigated to determine the possible phytochemical components from the solvents such as hexane, ethyl acetate and ethanolic extract of Justicia tranquebariensis. Among the phytochemical screening of these extracts, ethyl acetate extract showed that the whole plant was rich in carbohydrate, tannin, flavonoids, quinones, cardiac glycosides, phenols, steroids, and coumarins. Further, the study was extended by analyzing the antioxidant potential using DPPH method. Among all the extracts ethyl acetate and ethanolic extract showed better antioxidant activity at the concentration of 75 µg/ml when compared to hexane...
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