IN-VITRO ANTHELMINTIC ACTIVITY OF METHANOLIC LEAF EXTRACT OF ABRUS PRECATORIUS LINN. (FABACEAE)Abstract
The present study was aimed to the investigation of the anthelmintic potential of crude methanolic extract of the leaves of Abrus precatorius Linn. on Indian earth-worm “Pheretima posthum” and “Tubifex tubifex.” Three concentrations (5, 10, 15 mg/ml) of methanolic extract were studied in activity which involved the determination of the time of paralysis (vermifuge) and time of death (vermicidal) of the worms. Piperazine citrate (10 mg/ml) was used as reference standard drug whereas distilled water as the control. Determination of paralysis time and death time of the worms were recorded. The result shows that methanolic extract possesses vermicidal activity and found to be effective as an anthelmintic. Therefore, the anthelmintic activity of the methanolic extract of Abrus precatorius Linn. Leaves have been reported.
S. Selvadurai *, M. D. D. Raju, A. V. Rao and T. S. V. Kirubha
Department of Pharmacognosy, GIET School of Pharmacy, Rajahmundry, Andhra Pradesh, India.
11 July 2016
18 August 2016
27 August 2016
31 August 2016