Posted by admin on Oct 21, 2015 in |
In the present study, the photochemistry of fluoroquinolone antibiotic drug-besifloxacin (1) was investigated under mild conditions similar to those encountered in biological systems namely aerobic as well as an anaerobic condition with UV-A light. When besifloxacin (1) was irradiated with a high-pressure mercury lamp under aerobic conditions it afforded 7-(2-Amino-5-oxo-pentylamino)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo- 1, 4 – dihydro-quinoline-3-carboxylic acid as photoproduct (2) and under anaerobic condition it afforded 7-(3-Amino-azepan-1-yl)-1-cyclo propyl-6-fluoro-8-hydroxy-4-oxo-1,4dihydro-quinoline-3-carboxylic acid as photoproduct (3). The formation of photoproduct was explained by the type-I and type II mechanism of...
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Posted by admin on Oct 20, 2015 in |
A survey was conducted to collect information about the effective medicinal plants used by the Traditional healer to treat diabetes. The use of herbal drugs increased worldwide because of the lack of side effects and efficacy. Traditional healing is practicing throughout the world to treat several diseases. Glycemic disease has become a severe issue in India and all over the world. The traditional healer of West Godavari district studied for the use of medicinal plants to treat diabetes. We report 19 species of plants which are active against diabetes and about the scientific studies that have been conducted on...
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Posted by admin on Oct 20, 2015 in |
The use of ethnobotany practices to treat and control ruminant livestock diseases is old practices in large part of the world. To investigate Traditional medicinal plants used to treat ectoparasites in ruminant animals’ Semi-structured interview, observation and field guided walks were used with ruminant livestock owner, local and traditional healers who had willing to share their indigenous knowledge. The outcome of this study indicates that Phytolacca dodecandra, Calpurnia subdecandra, and Nicotiana glauca Graham are the dominant plants used by local people to treat ectoparasites in ruminant animals in the study area. These three plants were extracted by methanol for chemical information and accepted laboratory techniques were used for phytochemical determinations. Phytochemical analysis of methanol extract showed the presence of bioactive...
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Posted by admin on Oct 20, 2015 in |
Curcuma longa L. rhizomes are widely used by traditional medical practitioners for curing various diseases. The rhizomes of C. longa Linn. is commonly known as Haldi or Turmeric. Haldi is of particular importance to a human with the discovery that its rhizome powder, when added to various food preparations, preserves their freshness and imparts a characteristic flavor. The Indian system of medicine comprises of Ayurveda, Siddha, and Unani. In these systems, many medicines are made up of C. longa rhizomes. In Ayurveda, turmeric has been used internally as a stomachic, tonic, blood purifier and externally in the prevention and treatment of skin diseases. The World Health Organization (WHO) in 1999 had given a detailed protocol for quality control of single herbal drugs. We have developed a simple and rapid identification method for authentication of C. longa rhizome. Physicochemical parameters and TLC fingerprint analysis of C. longa rhizomes were also carried out. The study revealed different analytical parameters of the crude drug which will be useful in the identification of...
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Posted by admin on Oct 20, 2015 in |
Ethanol extract from the stem bark of Syzygium alternifolium exhibited significant activity against thioacetamide toxicity in rats. Glutamic oxaloacetic transaminase, alkaline phosphatase, total bilirubin, total cholesterol, lactate dehydrogenase, and total protein in serum indicated the hepatoprotective effect of the ethanol extract. Histopathological examination of liver sections confirmed that pre-treatment with ethanol extract prevented hepatic damage induced by thioacetamide. The results were compared with the standard hepatoprotective drug silymarin. The extract showed no signs of toxicity up to a dose level of 2000 mg/kg. It is suggested that the presence of flavonoids in ethanol extract may be responsible for hepatoprotective properties. Results indicate the hepatoprotective properties of ethanol extract of Syzygium...
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