Posted by admin on Sep 30, 2019 in |
Impatiens minor (DC.) Bennet (Balsaminaceae), a small, slender, erect herb, growing about 10 – 15 cm tall, with glassy stem, with oppositely arranged, elliptiac or ovate-lanceolate leaves and have distantly serrated margins is claimed to have many medicinal properties, but not scientifically proved properly. Systematic pharmacognostical evaluation of aerial parts of the plant has been carried out with focus on its macroscopy, microscopy, physic-chemical and phytochemical characterization. Macroscopical and microscopical features of stem and leaf have been documented. Preliminary phytochemical investigations indicated tests the presence of carbohydrates, alkaloids, triterpenoid, steroid, tannins, glycosides and flavonoids. The result of the study could be useful for the identification and preparation of a monograph of the...
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Posted by admin on Sep 30, 2019 in |
Hylocereus undatusis an important medicinal plant belonging to the family Cactaceae and widely distributed in tropical forest areas. Fruits are used for anti-bacterial, anti-oxidant, antipyretic, antidiabetic and hepato-protective activities of the plants are scientifically proved. The aim of the present study is to evaluate Hylocereus undatus pharmacologically for the anti-oxidant study. The study also includes the Pharmacognostical and phytochemical evaluation of the plant. The pharmacognostic evaluation revealed authentication and identification of the plant and extraction of plant material using ethanol by Soxhlets extraction method. Preliminary phytochemical studies were carried out using various chemical tests. Phytochemical studies showed the presence of glycoside, phenolic, flavonoids, triterpenoids, tannins and reducing sugar. The phenolic content of the ethyl acetate extract of the roots separated by chromatographic technique and the total phenolic content was calculated. Anti-oxidant activity studies using nitric oxide and DPPH scavenging assay showed that the ethyl acetate and aqueous extracts could be promising sources of natural...
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Posted by admin on Sep 30, 2019 in |
Objective: The aim of the study was to investigate the nephroprotective and hepatoprotective activity of methanolic extract of Clitoria ternatea in cisplatin and CCl4 induced in rats. Methods: Methanolic extract of aerial part of Clitoria ternatea plant was studied for its nephroprotective and hepatoprotective activity in animal experimental models. Nephrotoxicity was induced by cystone 16 mg/kg b.w. The standard drug was taken silymarin. The test drug was given methanolic extract Clitoria ternatea 500 mg/kg, 1000 mg/kg. Hepatoxicity was induced by CCl4. The standard drug was taken cisplatin 100 mg/kg. Test drugs were given extract of Clitoria ternatea 500 mg/kg and 1000 mg/kg as per b.w. Results: In hepatoprotective activity positive control group was provided with CCl4 and increased SGPT, SGOT, ALP level compare to negative control group whereas test 2 group was provided with methanolic extract of Clitoria ternatea 1000 mg/kg decreased SGPT, SGOT, ALP level compare to standard group. In nephroprotective activity positive control group was provided with CCl4 increased urea and creatinine level whereas test 2 group...
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Posted by admin on Aug 31, 2019 in |
The aim of this study was to identify the phytochemical groups of hydroethanolic leaf extract of Senna sieberiana DC and its fractions and to investigate their free radical scavenging activity. S. sieberiana leaves were extracted with a hydroethanolic solvent. From the hydroethanolic extract 3 fractions were obtained after a liquid/liquid fractionation (dichloromethane, ethyl acetate, and water). Phytochemical screening of the leaf extract and its fractions was done using standard reactions. Free radical scavenging activity was assessed using DPPH and ABTS assays. Tannins, flavonoids, anthracene derivatives, sterols, and triterpenoids were the main phytochemical constituents of the leaf extract and fractions. The hydro-ethanolic leaf extract of Senna sieberiana, its dichloromethane, ethyl acetate, and aqueous fractions and ascorbic acid had respective IC50 values of 191.6 ± 3.82; 495.73 ± 8.96; 165.8 ± 4.85; 50.40 ± 2.65; 19.53 ± 0.13 µg/ml in ABTS assay. In DPPH assay, the IC50 values were 44.8 ± 1.22; 218.93 ± 9.01; 32.13 ± 1.8; 26. 4 ± 0.11; 4.66 ± 0.07 µg/ml respectively for the leaf extract,...
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Posted by admin on Aug 31, 2019 in |
Growing burden of degenerative metabolic diseases can be addressed with help of traditional and folkloric medicine. The purpose of this study is to evaluate an ethanolic defatted extract (EDE) of Cipadessa baccifera (CB) leaf for anti-diabetic wound healing activity in male albino Wistar rats. The defatted and non-defatted extracts were prepared using water and ethanol solvent system. They were evaluated for pharmacognostic study, wound healing activity using animal excision and incision models. Antioxidant activity was performed using DPPH assay. Ascorbic acid was used as reference standard for determination of antioxidant activity. The antimicrobial activity was also carried out by disc diffusion and well diffusion method using chloramphenicol as reference standard. The EDE of leaf showed higher total phenolic content. It was found to be 389.2 mg gal/l. These extract showed good DPPH radical scavenging activity, which was found to be 68.75% in comparison with ascorbic acid. This extract also showed a good zone of inhibition with disc diffusion and well diffusion method. On 16th day, the 200 mg/kg EDE...
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