Posted by admin on Oct 10, 2024 in |
Dietary health supplements have been increasingly utilized in the prevention and treatment of chronic disorders. Over the past few decades, fenugreek (Trigonella foenum-graecum) seeds have been reported to exhibit hypoglycemic and cholesterol-lowering effects in both type 1 and type 2 diabetes mellitus patients, as well as in experimental diabetic animal models. The aim of this paper is to review the research findings on the use of fenugreek in diabetes management. There is compelling research evidence indicating that fenugreek can improve hyperglycemia and offer protection against diabetic complications through its immunomodulatory, insulin-stimulating, and antioxidant effects, as well as by enhancing adipocyte differentiation, reducing inflammation in adipose tissues, and preventing or mitigating pancreatic and renal damage. Many of the beneficial effects of fenugreek in diabetes have been attributed to four key bioactive components: diosgenin, 4-hydroxyisoleucine, furostanolic saponins, and its fiber...
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Posted by admin on Oct 10, 2024 in |
Chronic diabetic wounds are a common complication in individuals with diabetes and can lead to severe health issues if not treated quickly. Due to its capacity to improve cellular energy metabolism, Creatine monohydrate (CrM) has been suggested to possess potential health benefits. The effectiveness of a topical CrM formulation in healing chronic diabetic wounds in male Wistar rats was investigated in this research along with placebo, marketed formulation. Over the course of 21 days, the reduction of the wound and its fast pace of healing were observed. In contrast to the disease control group, the treatment group lesion size was significantly reduced and its wound closure rate was significantly higher. Increased collagen deposition and angiogenesis were also found by histological analysis in the CrM group, suggesting improved tissue regeneration. In conclusion, the topical CrM formulation showed encouraging benefits on wound healing and may have application in the therapeutic management of chronic diabetic...
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Posted by admin on Oct 10, 2024 in |
Artocarpus heterophyllus Lam, popularly known as Ceylon jack tree or jackfruit, evergreen tree reaching 8-25 m high, belongs to the family Moraceae. The trunk is straight, rarely buttressed, with a circumference of 50-100 cm. The stems are straight, forming a 30° angle with the trunk. The leaves are alternate, simple, pinnately veined, coriaceous, glossy, 4-25 cm long x 2-12 cm, dark green on the upper side and pale green beneath. The leaf has many therapeutic properties especially its diabetes control, antioxidant and anti-aging properties. Traditionally leaves are useful in fever, boils, wounds and skin diseases. In the present study, we discuss and highlight the recent findings concerning the different classes of RA therapies including the conventional and modern drug therapies. Approximately, one per cent of the world population lives with rheumatoid arthritis (RA), with at least twice as many women affected as men. Selection of leaves are important as compared to the other parts because it includes more constituents and also can be cheaply...
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Posted by admin on Aug 31, 2024 in |
This study investigates the antioxidant properties and chemical composition of Linum usitatissimum L. (flaxseed) extract using High Resolution-Liquid Chromatography Mass Spectrometry (HR-LCMS) analysis. The primary objective is to identify the bioactive compounds responsible for the antioxidant activity and evaluate the efficacy of flaxseed extracts prepared with different solvents, including methanol, ethanol, acetone, chloroform, petroleum ether, and ethyl acetate. Methodologically, the study employs various antioxidant assays such as DPPH, ABTS, FRAP, and total Antioxidant Activity (TAA), in conjunction with HR-LCMS analysis for comprehensive chemical profiling. Key findings reveal that methanolic and ethanolic extracts exhibit the highest antioxidant activities, with significant amounts of phenolic and flavonoid compounds identified. The HR-LCMS analysis further elucidates the presence of metabolites such as adenosine, abscisic acid glucose ester, and kaempferol 7-O-glucoside, which contribute to the observed bioactivity. The study concludes that flaxseed extracts, particularly those obtained with methanol and ethanol, possess substantial antioxidant potential, underscoring their potential application in nutraceuticals and functional...
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Posted by admin on Aug 31, 2024 in |
The aim of this study is to prepare and formulate an herbal shampoo and evaluate its physiochemical properties for safety and efficacy which contain safe natural ingredients. Shampoo is a hair care product used for the removals of dirt, oils, skin particles, environmental pollutants and other foreign particle which build up in hair. The shampoo is enriched with herbal extract without any synthetic additives. The herbal extract used in formulations are Punica grantum (pomegranate), Curcuma longa (turmeric), Sapindus mukorossi (ritha), Datura metal (datura), Pisidium guajira (guava), Azadinachta indica (neem), Hibiscus rosa-sinensis (shoe black plant), Citrus sinensis (orange), Zingiber officinale (ginger), Allium sativum (garlic), Allium cepa (onion), Cuminum cyminum (jeera). Herbal shampoo was prepared by simple mixing process. The herbal shampoo was tested for physicochemical properties. Some of methods are visual inspection, pH determination, solubility check, cleansing action, determination of percentage solid content, viscosity evaluation, dirt dispersion, foaming ability detergency ability and stability...
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