Posted by admin on Jun 30, 2025 in |
This study evaluated the antibacterial activity of eight commercially available toothpaste samples (P1–P8) and a standard antibiotic control (Tetracycline) against three oral bacterial isolates (C2, C3, C4) and Escherichia coli using the well diffusion method. Zones of inhibition were measured to assess antimicrobial efficacy. Among all samples, P1 demonstrated the highest activity, with inhibition zones surpassing those of the antibiotic control for several strains. P8 exhibited consistent activity across all bacteria, while P2 was selectively effective against C3. In contrast, P4, P6, and P7 showed no activity against E. coli. Notably, E. coli resistance to several formulations underscores the need for rigorous post– brushing rinsing to minimize potential impacts on gut microbiota. The results affirm that antibacterial efficacy varies widely among commercial toothpaste brands, likely due to differences in formulation and active components. This study highlights the superior antibacterial action of certain commercial toothpastes compared to antibiotics and also underscores the importance of product–specific evaluation for effective oral health...
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Posted by admin on Jun 30, 2025 in |
Background: Colocasia gigantea is a large, stemless, tuberous, frost-tender perennial of the arum family, which typically grows tall and wide. It is found abundantly in tropical countries, and in Southeast Asia. Methodology and Results: Phytochemical analysis using gas chromatography and acute toxicity testing was done on methanolic leaf extract of Colocasia gigantea. The adult male wistar rats used for acute toxicity testing were 13 in number. The results showed that at 5000mg/kg, of administration of methanolic leaf extract Colocasia gigantean, no death occurred among the wistar rats used for the study. Phytochemical analysis results on methanolic leaf extract of Colocasia gigantea showed the presence of flavonoids (flavon – 3-ol and flavone), alkaloids, tannins, nobiletin, artemetin. Conclusion: Methanolic leaf extract of Colocasia gigantea contains substances of significant medicinal values and acute administration of methanolic leaf extract is relatively...
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Posted by admin on Apr 30, 2025 in |
Plants have been used for medical purposes since prehistoric periods. Approximately 60% of the world population and 80% of the population of developing countries depend on traditional medicinal plants due to their safety, accessibility, affordability and they are more economic. Inflammation of the joints is known as arthritis. More than 100 distinct forms of arthritis and associated disorders that affect the joints are referred to as arthritis, which is not a single illness. The connective tissue that envelops joints and other tissues. Anti- arthritic activity was mainly reducing the total leukocyte migration as well as lymphocyte and the monocytes / macrophage migration. The current study was designed to evaluate the in-vitro anti- arthritic activity of various extracts like Pet ether, Chloroform, Ethanol, Aqueous of Ficus auriculata Lour leaves. The extraction was done by using Soxhlet apparatus method (Pet ether, Chloroform, Ethanol) and maceration method was done for aqueous extract and the extract was subjected to phytochemical screening. The in vitro anti arthritic activity of various extracts was performed by...
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Posted by admin on Apr 30, 2025 in |
The complication most feared by diabetics remains the diabetic foot, due to the risk of amputation. Terminalia ivorensis belongs to the Combrétacée family and is rich in secondary metabolite products. Studies have shown that Terminalia ivorensis has antifungal potentiaĺ and is traditionally used to treat wounds. Topical application based on Terminalia ivorensis on wounds of rats rendered diabetic showed a rapprochement between the results given by this application and L-mesitran® used as a reference molecule. The aqueous extract at different concentrations (500, 1000 mg/ml) showed significant healing activitý after topical administration in...
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Posted by admin on Apr 30, 2025 in |
Ficus mucuso Welw. ex Ficalho (Moraceae) is a plant used to treat the after-effects of strokes in Côte d’Ivoire. The aim of the present work is to characterize the physicochemical properties of the stem bark of this plant drug, evaluate its anti-inflammatory properties and determine the presence of minerals of interest in post-stroke treatment. Minerals play a crucial role in stroke prevention and management. Physicochemical tests revealed that Ficus mucuso stem bark has a pH of 5.81, a fairly low average water content (7.98%), a relatively high average dry matter content (92.02%), an ash content of 9.21%, and is rich in iron, potassium, magnesium and calcium, important minerals in stroke prevention and management. EAq has the highest concentrations of Potassium (160±11.3 mg/L) and Calcium (11±1.05 mg/L), while EEt has the highest concentrations of Magnesium (2.3 ± 0.12 mg/L) and Iron (1.38 ± 0.04 mg/L). Ficus mucuso stem ecore extract also has anti-inflammatory activity. Aqueous and ethanolic extracts of Ficus mucuso stem bark induce inhibition of protein denaturation at concentrations...
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