Herbal drugs play an important role in the health care programme especially in developing countries. Ancient Indian literature incorporates a remarkably broad definition of medicinal plants and considers “all” plant parts to be potential sources of medicinal substances. C. paniculatus is one of the Indian medicinal plants having a remarkable reputation as a factor of health care among the indigenous medicinal practitioner. There are many species of C. paniculatus which are medicinally important, but having very similar characters which makes confusion among the people about its authentification. As pharmacognosy is the 1st step in proving medicinal status as the crude drug of plant parts used in the health care system, the preliminary phytochemical studies of seeds, leaves, stem, and root of C. paniculatus were carried...Read More
PHYSICO-CHEMICAL AND NATURAL PRODUCT INVESTIGATIONS OF ESSENTIAL OIL AND VARIOUSLY EXTRACTED MEDICINALLY USEFUL MATERIALS FROM THE RHIZOMES OF ALPINIA SPECIOSA K. SCHUM.
Essential oil isolated from the rhizomes of Alpinia speciosa K. Schum. by hydrodistillation has a yield of 0.69 percent by weight. Light yellow oil from Alpinia speciosa has a spicy odor; specific gravity 0.8577; optical rotation +6o30′. Acid and saponification values are also determined and reported. Extractions of medicinally useful materials separately through solvents of decreasing polarities, viz., water, ethanol, diethyl ether, and petroleum ether are carried out from its rhizome. Ethanol extract has a maximum yield. Odors vary in differently extracted materials. Diethyl ether and petroleum ether extracted materials show a sufficient degree of unsaturation. The essential oil is dextrorotatory. All of the solvent extracted materials are dextrorotatory. Specific gravities, refractive indices, acid, saponification and iodine values of these variously extracted materials are also reported. Tests for the presence of specific natural products indicate the presence of carbohydrates, flavonoids, and steroids in most of the extracted...Read More
The literature survey reveals that the plant Raphanus sativus belongs to the family Cruciferae. It is widely used to treat the viral, bacterial infection, antihepatotoxicity anti lithiasis, Hypolipidaemic, inflammation, and cancer. The study focused on the phytochemical screening of the ethanolic extract of radish bulbs (Raphanus sativus). The molecular masses to provide probable structures and associated molecular properties for its constituents. Alkaloids, flavonoids, saponins, and tannins were analyzed. The following research shows the anticonvulsant activity of R. sativus. Anxiety is an overwhelming sense of uneasiness or discomfort. We have important plants reported anxiolytic activity, uses, models and doses for anxiolytic activity &...Read More
Aim: The objective of this study was to evaluate the effect of Commiphora mukul on psoriasis. Materials and Methods: Six female Balb/C mice per group of which, the first three groups served as untreated, disease controls and standard (0.1% dexamethasone) respectively. Animals of groups 4, 5 and 6 were applied 0.5, 1 and 2% of the C. mukul extract on both the ears, respectively. Dermatitis was induced in mice by the application of oxazolone 1.5% (100 µL in ethanol) to the abdominal region for six days. Starting seven days following sensitization, 20 µL of oxazolone 1% in a mixture of acetone and olive oil (4:1) was applied to both sides of the mouse ear on days 7, 10, 13 and 16. For detailed time-course analysis of swelling ear reactions, ear thickness was measured before the sensitization phase (day 7) and after each elicitation on days 10, 13, 16 and 19. Results: C. mukul potently suppressed ear swelling at each time-point. The suppressive rates of C. mukul at concentrations of...Read More
Siddha system is one of the oldest and most ancient traditional prevailing medicinal systems in India especially in our south India. In our system, first preference is given for plant-based medicine. Plant-derived drugs have been a part of the evolution of human health care for thousands of years in India. Elathi kuligai is prepared as per classical Siddha textbook for the respiratory problem in the pediatric age group. It is a poly herbal drug preparation. Before conducting a clinical trial, the preclinical study should be undergone as per WHO guidelines. The present preclinical study aim is to carry out the safety and toxicity of Elathi kuligai . Male and female Wistar rats of age 6 – 8 weeks old. Weighing 220–240 gm was used for this study. Acute and Sub-acute toxicity were carried out as per OECD guidelines 423 and 407. Hematological parameters, biochemical parameters, histopathological study were performed for all animals. The study concludes that on oral administration of dose level of 200mg/kg and 400 mg/kg of body...Read More