Posted by admin on Apr 6, 2015 in |
A rapid, simple, selective and precise UV-Visible spectrophotometric method has been developed for the determination of Curcumin in bulk and nano-formulation. The spectrophotometric detection was carried out at an absorption maximum of 421 nm using methanol as solvent. The method was validated for various validation parameters. The linearity range was found to be 5-25 μg/ml with a correlation coefficient of 0.9997. The accuracy was found to be within the limit. The LOD and LOQ were found to be 0.4 and 1.21 μg/ml; respectively. The results demonstrated that the method could be conveniently employed for routine quality control analysis of Curcumin in bulk and...
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Posted by admin on Apr 6, 2015 in |
Rauwolfia serpentina has a great reputation as a miracle medicinal plant, reported in various texts of the indigenous system of medicine. As, free radicals and diseases have great correlation; therefore, in the present study, free radical scavenging activity of methanolic extract (MET) of rhizomes of mature Rauwolfia serpentina was investigated by using CCl4 induced hepatotoxicity model in albino rats. The MET exhibited significant free radical scavenging activity by showing increased levels glutathione peroxidase (GPX), glutathione-S-transferase (GST), glutathione reductase (GRD), superoxide dismutase (SOD), catalase (CAT), glutathione (GSH) and decreased the level of lipid peroxidation (LPO). The MET, at a dose level of 400 mg kg-1 showed significant free radical scavenging activity against CCl4 induced liver injury in rats. MET of R. serpentine had been shown prominent antioxidant activity and CCl4 intoxicated liver recovery towards...
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Posted by admin on Apr 6, 2015 in |
Aqer Qerha (Anacyclus pyrethrum DC.), family Asteraceae is a perennial, procumbent herb, native to North Africa and Arab countries and in India, it is found in the Himalayas, Jammu and Kashmir, and North India. In Unani System of Medicine, it is an effective remedy for the treatment of a variety of diseases. The plant roots are reported for muhallil-e-awram (anti-inflammatory), muqawwi-e-bah (anabolic & aphrodisiac) Moqawwi and moharrik-e-aasab (tonic and stimulant of nerves) and used for laqwa (facial paralysis), falij (hemiplegia), sara (epilepsy), loosening of teeth, isterkha-e-luhat (flaccidity of uvula) and luknat-e-zuban (stammering), single as well as its compound formulations like gargle, decoction, liniment, majun, oil etc. The roots contain a colorless crystalline acid-amide known as pellitorine (pyrethrins) possesses an intensely pungent taste and produces a sialogogue effect, The other phytoconstituents reported in the plant include N-isobutyldienediynamide, polysaccharides hydrocarolin, inulin, traces of volatile oil and...
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Posted by admin on Apr 6, 2015 in |
As we are well aware that the production of metallic nanoparticles by the physical and chemical method has numerous drawbacks along with the use of toxic chemicals, high energy expenditure and non- biodegradable products. Hence, researchers are showing great interest in the biological synthesis of nanoparticles. The biological method provides clean, bio-degradable, non-toxic and eco-friendly methods for nanoparticles synthesis as compared to a conventional method like physical and chemical. This review concentrates on biological method specially biosynthesis of different types of nanoparticles using bacteria and their application in different...
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Posted by admin on Apr 6, 2015 in |
Flavonoids are common plant constituents used extensively in phytomedicine to treat a wide range of diseases. Many pharmacological pieces of evidence suggest that flavonoids may play an important role in the decreased risk of chronic diseases associated with a diet rich in plant-derived foods. Therefore, this article focuses on the chemistry, distribution and pharmacological properties of rhoifolin as one of the common and important flavonoids in the plant kingdom. This flavonoid has also been found in several dietary sources such as bitter orange, bergamot, grapefruit, lemon, lupinus, lablab beans, tomatoes, artichoke, bananas, and grapes. Preclinical studies have shown that rhoifolin possesses a variety of significant biological activities including antioxidant, anti-inflammatory, antimicrobial, hepatoprotective and anticancer effects. The literature search was conducted using electronic databases (e.g., Medline, Pubmed, Academic Journals and Springer Link), general web searches were also undertaken using Google applying some related search, journals and scientific theses. The bibliographies of papers relating to the review subject were also searched for further relevant...
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