Posted by admin on Jul 31, 2019 in |
Natural products are an important source of bioactive compounds and have potential for the development of novel therapeutics. Natural products and their derivatives represent more than 50% of all drugs in clinical use in the world. Herbal plants contain and produce a verity of chemical substances used as a remedy for treating diseases. Anthelmintic and antioxidants have been treated with some medicinal plants or their extract based on folklore medicine. For the research Polygala chainensis and Cleome chelidonii selected based on its availability, high therapeutic value; activity has not been scientifically investigated. Very few pharmacological activities have been reported on whole plant of Polygala chainensis and Cleome chelidonii. The leaves of Cleome chelidonii and Polygala chinensis plants was observed for the phytochemical investigation and pharmacological evaluation. The percentage of yield and phytochemical was observed in methanolic extraction so this extraction was used for pharmacological activity. The extract of Cleome chelidonii and Polygala chinensis plants shown anthelmintic activity. The anthelmintic activity of Polygala chinensis was better than Cleome chelidonii. Significant...
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Posted by admin on Jul 31, 2019 in |
Tinospora cordifolia (T. col.), a plant which has great significance in the Ayurvedic system of medicine, has been tested according to modern medical techniques for numerous therapeutic effects like immunomodulation, reducing tumor cells, purification of blood, reducing fatty lipids from body, reduction of glucose and increasing glucose tolerance in case of diabetes and increasing body weight. T. col has been used even during various rheumatic diseases like rheumatoid arthritis and has shown positive therapeutic effects. T. col. reduces the unwanted lipids. It enhances the humoral immune response. It also cleans out the immune complexes from the body. T. col. acts as an adaptogen. It has been reported to both increase and decrease activities of substances in the body, so as to normalize its functionality. It enhances immunity, but on the other hand, it inhibits autoimmunity. This paper is a review of the findings of the medical benefits of T. col., and combining all the information to propose that this plant may be used in the treatment of another rheumatic...
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Posted by admin on Jul 31, 2019 in |
Ocimum tenuiflorum Linn. commonly known as holy basil, tulsi is an aromatic perennial plant in the family Lamiaceae. It is native to the Indian subcontinent and cultivated plant throughout the Southeast Asian tropics, where the leaves, seeds ad stem of tulsi are used for valuable source of culinary and traditional medicinal uses. Indian material medica describes the use of the plants in a variety of ailments such as immunostimulatory effect, gastric antiulcer activity, diabetics mellitus, hyperlipidemia, wound healing effects, protective effect, chemopreventive activity, and blood pressure, etc. The present review aims to summarize up to date information on the ethnomedicinal, phytochemical and pharmacological activity. Until now, highly complex natural molecules have identified including fixed oils, essential oils, triterpenes, flavonoids, flavonoid glycosides, polysaccharides, phenolic glycoside, lignans, and norlignans. In addition to solvent extracts, these individual active compounds have been suggested for ethano-pharmacological activities. Although the results are promising in-vitro and in-vivo preclinical studies, clinical studies are insufficient; therefore, further investigation of each active compound need to be done to validate...
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Posted by admin on Jun 30, 2018 in |
The aim of the present work was to investigate the anti-diarrheal and diuretic potentials of Tabernaemontana divaricata Linn. leaves of the family Apocynaceae. In almost all tropical developing countries of the world, diarrhoea is one of the most common and serious diseases, the principal cause of morbidity and mortality among children under five years. The methanolic extract of the leaves of T. divaricata L. was evaluated for anti-diarrheal properties in castor-oil induced diarrhoea. In the castor oil induced diarrhoea, MELTD significantly inhibited the number of defecations. The diuretic activity of the methanolic extract of leaves of T. divaricata (MELTD) was assessed based on Lipschitz value and diuretic index. The standard diuretic drug furosemide exhibited a significant increase in the urinary excretion of water and electrolytes (Na+ and K+), which is comparable with the extract. The diuretic index at the dose of 200 mg/kg (MELTD) was calculated as 1.55, significant as compare to the standard drug having a diuretic index of...
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Posted by admin on Jun 30, 2018 in |
Ficus polita leaves have been used in traditional medicines to increase physical strength, work productivity and longevity, resistance to high altitude sickness, fatigue, depression, anemia, gastrointestinal ailments, infections, and nervous system disorders. The objective of this study was to evaluate the analgesic activity of hydromethanolic extract of F. polita leaves in rats using acetic acid-induced writhing and tail flick immersion methods. The phytochemical screening of the extract revealed the presence of flavonoids, saponins, terpenoids, glycosides, resins, steroids, balsams and pholobatannins. Acute oral toxicity study resulted in no mortality after oral administration of 3000 mg/kg of the extract. Based on the tail flick immersion test, Ficus polita hydromethanolic leaves extract and the standard drug, diclofenac showed significant (P<0.05) analgesic activity by prolonging the mean latency time when compared to the control. However, a significantly (P<0.001) prolonged mean reaction latency to pain in morphine-treated groups was not comparable to the extract and diclofenac treated groups. The extract and the standard drugs significantly (P<0.001) inhibited the acetic acid-induced abdominal writhing at all...
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