ETHANOMEDICINAL, PHYTOCHEMICAL AND PHARMACOLOGICAL INVESTIGATION OF OCIMUM TENUIFLORUM LINN.Abstract
Ocimum tenuiflorum Linn. commonly known as holy basil, tulsi is an aromatic perennial plant in the family Lamiaceae. It is native to the Indian subcontinent and cultivated plant throughout the Southeast Asian tropics, where the leaves, seeds ad stem of tulsi are used for valuable source of culinary and traditional medicinal uses. Indian material medica describes the use of the plants in a variety of ailments such as immunostimulatory effect, gastric antiulcer activity, diabetics mellitus, hyperlipidemia, wound healing effects, protective effect, chemopreventive activity, and blood pressure, etc. The present review aims to summarize up to date information on the ethnomedicinal, phytochemical and pharmacological activity. Until now, highly complex natural molecules have identified including fixed oils, essential oils, triterpenes, flavonoids, flavonoid glycosides, polysaccharides, phenolic glycoside, lignans, and norlignans. In addition to solvent extracts, these individual active compounds have been suggested for ethano-pharmacological activities. Although the results are promising in-vitro and in-vivo preclinical studies, clinical studies are insufficient; therefore, further investigation of each active compound need to be done to validate its therapeutic effects and to ensure its toxicity, safety, and efficacy.
U. K. Ilyas, D. P. Katare and V. Aeri *
Department of Pharmacognosy and Phytochemistry, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, Delhi, India.
28 June 2019
18 July 2019
29 July 2019
31 July 2019