Posted by admin on Jun 3, 2015 in |
The medicinal plants have attracted great attention in recent years for better therapeutic management of diseases. Nigella sativa is one of the most extensively studied plants and has gained more and more interest in potential medical use in recent years. Historical and traditional uses of this herb have been widely documented in ancient documents; and Nigella sativa has been broadly used throughout the world for the promotion of health and the treatment of many acute, as well as, chronic conditions for centuries. The seeds of Nigella sativa have rich biological active compounds, and are used as a natural remedy to treat various ailments since it has a variety of pharmacological properties, which include anti-oxidant, anti-inflammatory, immuno-potentiating actions, anti-cancer, analgesic, anti-histaminic, anti-microbial, hypoglycemic, gastroprotective, nephroprotective, lung protective, cardioprotective, hepatoprotective, and neuroprotective. This plant also has positive effects on the reproductive system and skin diseases. On the other side, adverse effects and toxicity about the use of Nigella sativa were rarely reported. An ingredient isolated from seeds and evaluated mostly is...
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Posted by admin on May 1, 2014 in |
Pharmacognostical parameters for the leaves including petiole of Kailaspati was studied with the aim of drawing the Pharmacognostical standards for this species. Macroscopical and microscopical characters of leaves and petiole, powder characteristics studies, fluorescence studies and thin layer chromatographic studies of the leaves powder included. The study also deals with the preliminary phytochemical screening of the leaves and petioles of Kailaspati with various extracts such as petroleum ether to water. Glandular, non-glandular trichomes and starch grains were identified. The qualitative analysis of some secondary metabolites, to ascertain medicinal claims of this widely used medicinal plant. The results showed that the moderate presence of oils, alkaloids, glycosides, flavonoids, ketosteroids, amino acids, phenols, and triterpenoids. The study includes pharmacognostical standardization of Kailaspati with petiole first...
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Posted by admin on May 1, 2014 in |
The ethanol extracts of stem bark of Synedrella nodiflora belonging to the family of Asteraceae was studied for hepatoprotective activity against Swiss Albino Rats with liver damage induced by carbon tetrachloride (CCl4). It was found that the ethanol extract of Synedrella nodiflora at a dose of 250 mg/kg body weight exhibited significant protective effect by lowering the serum level of alanine aminotransferase (ALT) or serum Glutamate Pyruvate Transferase (SGPT), and 100 mg/kg body weight exhibited significant protective effect by lowering both the serum levels of alanine aminotransferase (ALT) or serum Glutamate Pyruvate Transferase (SGPT), aspartate aminotransferase (AST) or serum glutamate oxaloacetate transaminase (SGOT). The highest hepato-protective activity was observed for ethanol extract of Synedrella nodiflora at a dose of 250 mg/kg body weight, and the reduction of serum level of ALT, AST and serum bilirubin were 60.918 ± 0.7936, 81.479 ± 2.85039 and 0.5205 ± 0.0249 respectively. Since, result of biochemical studies of blood sample of carbon tetrachloride treated rats showed significant increase in the level of serum enzyme...
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Posted by admin on May 1, 2014 in |
Plants have been used for centuries as a remedy for human diseases because they contain phytochemical components of therapeutic values. The whole plant of the Trigonella foenum, Zea mays and Oryza sativa were selected for in this study to find out the phytochemicals and antioxidant property. Phytochemicals were extracted using various solvents such as Hexane, Ethyl acetate, and ethanol. Screening of phytochemicals showed positive results for the presence of flavonoid, alkaloid, phenols, coumarins, steroids, and quinones. Free radical scavenging activity was determined using DPPH is a stable antioxidant. Ethyl acetate extract of Zea mays showed better antioxidant activity at a concentration of 100-150 µg followed by ethanol extract. An ethanol extract of Trigonella foenum revealed antioxidant activity at a concentration of 100-150 µg followed by ethyl acetate extract. These activities may be due to the presence of flavonoid, alkaloid, phenols, and steroids in plant extracts. Antioxidant activity was not observed in Oryza...
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Posted by admin on May 1, 2014 in |
Rheumatoid arthritis (RA) is a chronic systemic disease which results in pain, swelling, and stiffness in joints. It affects about 1% of the total world’s population. RA begins with an edematous thickening of the synovia which latter converts into inflammatory synovium called pannus which erodes the surrounding cartilage. Conventional therapy exists to overcome illness but prolonged uses of drugs cause various side effects. Several reports demonstrate herbal remedy for RA treatment. Saffron is the natural yellow spice derived from the flower of Crocus sativus, possess antioxidant, anti-inflammatory activities. Therefore, in this study role of saffron for its treatment has been explored in AIA mice. The effect of three doses of ethanolic extracts of Crocus sativus (Family: Iridaceae) on adjuvant-induced arthritic mice was examined and evaluated. FCA injection caused a significant increase in joint inflammation. A daily oral dose of Crocus sativus extract (CSE) for 47 days resulted in a significant decrease in Lipid peroxides level as compared to AIA mice, while on the other hand the significant increase in...
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