Trianthema decandra Linn., belongs to family Aizoaceae, commonly known as “Punarnavi” in Sanskrit, “Gadabandi” in Hindi, and “Vellai sharuni” in Tamil. This plant is globally distributed tropical and subtropical regions. In India, it grows in dry-soil lands. It has been known since ancient times for curative properties and has been utilized for treatment of various ailments such as burns and wounds. The roots are aperients and said to be useful in hepatitis, asthma, and suppression of the menses. A decoction of the root-bark is given as an aperients. The juice of the leaves dropped into the nostrils relieves one-sided headache. 1 In the present investigation, the detailed Pharmacognostic study of Trianthema decandra root is carried out to lay down the standards, which could be useful in future Forensic identification of unknown plant material. Results: The study includes macroscopic, microscopic, preliminary phytochemical screening and physicochemical evaluation. The objective this was to characterize the unknown plant material. Conclusion: In recent years there has been a rapid increase in the standardization of...Read More
ANALGESIC ACTIVITY OF CINNAMALDEHYDE PER SE AND IT’S INTERACTION WITH DICLOFENAC SODIUM AND PENTAZOCINE IN SWISS ALBINO MICE.
Cinnamon is one of the best-known spices used as herbal medicine. Cinnamaldehyde is the most important constituents of cinnamon. The present study was aimed to evaluate the analgesic activity of Cinnamaldehyde per se and its interaction with diclofenac sodium and pentazocine in Swiss albino mice. Healthy mice of either sex weighing 20-30 grams were divided into 6 groups of 6 animals each. Peripheral analgesic activity was evaluated by acetic acid induced writhing test, and central analgesic activity was studied using Eddy’s hot plate method. Cinnamaldehyde (100 and 200 mg/kg) and its combination (Cinnamaldehyde 100 + 2.5 mg/kg standard drug), diclofenac sodium (2.5 and 5 mg/kg) and pentazocine (2.5 and 5 mg/kg) were given orally. Acetic acid induced writhing model showed that diclofenac sodium at doses of 2.5 and 5 mg/kg reduces writhing 44% and 66% respectively as compared to control when administered alone. Cinnamaldehyde at 100 and 200 mg/kg showed dose-dependent decrease in writhes 54% and 81%, but when Cinnamaldehyde (100 mg/kg) was co-administered with diclofenac sodium (2.5mg/kg) showed...Read More
PHYTOCHEMICAL SCREENING AND FRACTIONATION OF MOMORDICA CHARANTIA LINN. FRUIT TO SHOW ANTIHYPERGLYCAEMIC ACTIVITY
Diabetes mellitus is a metabolic disorder in the endocrine system. This dreadful disease is found in all parts of the world and is becoming a serious threat to mankind health. There are lots of chemical agents available to control and to treat diabetic patients, but total recovery from diabetes has not been reported up to this date. An alternative to these synthetic agents, plants provide a potential source of hypoglycemic drugs and are widely used in several traditional systems of medicine to prevent diabetes. Several medicinal plants have been investigated for their beneficial use in different types of diabetes. The effects of these plants may delay the development of diabetic complications and correct the metabolic abnormalities using a variety of mechanisms. whole fruit of Momordica charantia was selected in this study to find out the phytochemicals & antidiabetic property. Phytochemicals were extracted using water. For the current article screening of alkaloid, carbohydrates, glycosides, flavonoids, proteins, tannins & phenolic compounds and also done single dose antidiabetic activity. Screening of phytochemicals...Read More
Sonchus arvensis, a perennial sowthistle, is a common but underutilized species of Kathmandu, Nepal. Several uses like sedative, antioxidant and kidney stone eradicating properties have been identified till date, but a study on other pharmacological activities is not yet explored. Therefore, the plant was collected from Kathmandu; aerial parts of the plant were dried, crushed, and extracted using a Soxhlet apparatus. The methanolic extract was then concentrated for screening pharmacological effects. While comparing with the standards, the plant was found to possess potent anti-inflammatory activity and inhibitory effect in Gastro-Intestinal (GI) motility and locomotor activity in a dose-dependent fashion. The plant, however, didn’t show skeletal muscle relaxant activity as observed in the traction test and inclined plane test. Thus, it is concluded that the plant possesses strong phytochemicals having anti-inflammatory activity and inhibitory effect in locomotion and GI...Read More
ANTI CANCER PROPERTIES OF PLANTS PRESENT IN WEST GODAVARI DISTRICT OF ANDHRA PRADESH, INDIA- A MINI REVIEW
Cancer is a fatal disease characterized by the abnormal growth of cells. Various factors cause cancer. Synthetic modern medicines have high toxic effects on other systems of the body such as renal system, circulatory system, etc. To reduce those toxic effects the scientific world is trying to find inhibitors from the herbal sources. Always the plants proved to be effective and efficient in curing fatal diseases. In this review, an attempt has been made to review the some of the medicinal plants such as Allium sativum, Aloe vera, Curcuma longa, Picrorhiza kurroa, Withania somnifera, Ananas cosmosus, Annona squamosa, etc., of about 10 species that have anti-cancerous activity present in West Godavari district of Andhra Pradesh,...Read More