Posted by admin on Mar 13, 2016 in |
Medicinal plants are bioresources harnessed by humans to combat diseases and maintain a healthy life. Plants remain the basis for the development of modern drugs for the preservation of health. Garcinia kola is considered a “wonder plant” because every part of it has been found to be of medicinal importance. G. kola seed is used as an antipyretic agent in indigenous system of medicine. Pharmacologic studies on the seed, leaf, and root of this plant showed potent antimicrobial, antiviral, antiulcer, anti-inflammatory, antihepatotoxic, antidiabetic, antihypertensive, adaptogenic, aphrodisiac and antiasthma activities. This review highlights detailed pharmacological properties and phytochemistry of G. kola in an attempt to provide direction for further research toward drug...
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Posted by admin on Mar 13, 2016 in |
Cancer is a disease of deregulated cellular behavior. Acquisition of oncogenic attributes, loss of tumor suppressive functions, evasion of physiological tissue architecture and interactions with the cellular microenvironment enable malignant cells to escape the mechanisms of normal cellular homeostasis in an organism. Cancer cells are therefore able to sustain unlimited proliferation, to thrive under conditions that preclude normal cell survival, and to spread to distant sites through the process of metastasis. Natural products are important sources of new anticancer drugs, new drug leads and new chemical entities. The plant-based drug discovery resulted mainly in the development of anticancer agents including plants (vincristine, vinblastine, paclitaxel, etoposide, camptothecin, topotecan, and irinotecan). Beside this there are numerous agents identified from fruits and vegetables can use in anticancer therapy. The agents include curcumin (turmeric), resveratrol (red grapes, peanuts and berries), genistein (soybean), diallyl sulfide (allium), S-allyl cysteine (allium), allicin (garlic), lycopene (tomato), capsaicin (red chilli), diosgenin (fenugreek), 6-gingerol (ginger), ellagic acid (pomegranate), ursolic acid (apple, pears, prunes), silymarin (milk thistle), anethol (anise, camphor,...
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Posted by admin on Feb 28, 2015 in |
Background: Gilbert’s syndrome (GS) is the most common form of congenital, non haemolytic, mild unconjugated hyperbilirubinaemia. Familial cases linked with mutation in enzyme UDP glucuronosyl transferase 1 producing decreased conjugation of bilirubin which accumulates in the form of unconjugated bilirubin. Hyperbilirubinaemia is mild (<6 mg/dl) while liver enzymes & histology are always found normal. It is clinically characterized by vague symptoms like loss of appetite, abdominal pain, weight loss and mild Jaundice. A review of Unani literature showed disease similarity clinically with Su-e-Mizaj Jigar Har Yabis, with dominating features of Safra (yellow bile). Material and Methods: We report our experience with such a case of GS by validated integrative assessment and management with Unani medicine e.g. Arqayat (Makoh+Kasni+Biranjasif), Jigreen, Sharbat-e-Bazoori and Majoon Dabid-ul-Ward along with a short review of literature. Results were analyzed based on clinical and LFT outcomes. Results: Significant symptomatic relief was achieved over 5 weeks of treatment. Bilirubin levels normalized but rose after 5 weeks. Literature review showed disease similarity with Su-e-Mizaj Har Yabis Sadaa which...
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Posted by admin on Feb 28, 2015 in |
Raphanus sativus commonly known as radish is cultivated as a crop and having various medicinal uses. It is cultivated all over the world as an edible root vegetable. The present study deals with the pharmacognostic, preliminary phytochemical investigation of Raphanus sativus, Linn. belonging to family Cruciferae. In this, pharmacognostic studies are concerned for the determination of physicochemical parameters like ash values, extractive values, and loss on drying, fluorescence analysis also the macroscopic and microscopic evaluation carried out. The leaves were subjected to successive soxhlation using petroleum ether, ethyl acetate, alcohol, and water. The extracts thus obtained were studied for preliminary phytochemical investigation for detection of the presence of various chemical constituents like alkaloids, glycosides, steroids, tannins, saponins, fats and oils, flavonoids,...
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Posted by admin on Feb 28, 2015 in |
Vitamin C, also known as ascorbic acid, is a water-soluble antioxidant vitamin having important nutritional and health benefits. Adequate consumption of fruits, vegetables and their juices with high vitamin C content and antioxidant capacity result in improved health, reduced risk of chronic diseases, optimal nutrition and general well-being. Thus, it is essential that vitamin C content in food items, intended to provide its supplement, is determined and its amount stated on labels of packages. The objective of the present study was to determine and compare the vitamin C content of fresh and commercial juices made from mango and orange. Fruits and packed juices were purchased from the local market of Mekelle city, Ethiopia. Iodine titration method was employed to determine the vitamin C content of test sample juices. Results showed that the amount of vitamin C was more in fresh juice than the corresponding packed juice in both mango and orange. For the fresh juices, the amount of vitamin C was more in orange than in mango while for...
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