Posted by admin on Feb 28, 2026 in |
Millets are ancient small-seeded cereal crops that have sustained human populations for thousands of years, particularly in the arid and semi-arid regions of Asia and Africa. This review highlights the historical importance, domestication, cultural relevance, agro-biodiversity, nutritional value, and contemporary significance of millets and pseudo-millets in food systems. Millets are recognized for their drought tolerance, climate resilience, and suitability for low-input agricultural systems, making them valuable crops under changing environmental conditions. The review also discusses their superior nutritional profile, including dietary fibre, essential minerals, bioactive compounds, and low glycemic index, which support their role in addressing malnutrition, hidden hunger, and lifestyle-related disorders. In addition, the article examines the applications of millets in food technology and nutraceutical product development, such as bakery products, fermented foods, gluten-free formulations, dietary supplements, and fortified foods. Policy support, value-chain development, and renewed global attention, especially during the International Year of Millets 2023, have further strengthened the relevance of these crops. Overall, the review emphasizes that millets represent not only a link to traditional agriculture...
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Posted by admin on Feb 28, 2026 in |
The present study evaluates the antidiabetic potential of hydroalcoholic extracts derived from the fruit and peel of Ananas comosus (pineapple). Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia resulting from impaired insulin secretion or action. Natural plant-based remedies have gained attention for their efficacy and minimal side effects. The hydroalcoholic extracts were prepared using standardized extraction methods and subjected to phytochemical screening to identify bioactive constituents. The antidiabetic activity was assessed using in-vivo models of diabetes induced in experimental animals. Blood glucose levels and body weight were monitored throughout the treatment period. Results demonstrated a significant reduction in fasting blood glucose levels and improvement in lipid profile in animals treated with both fruit and peel extracts, with peel extract exhibiting comparatively higher efficacy. The findings suggest that Ananas comosus hydroalcoholic extracts possess promising antidiabetic properties, potentially attributable to their rich phytochemical content, including flavonoids, phenolics, and enzymes. These results warrant further studies to isolate specific active compounds and elucidate underlying mechanisms for clinical application in diabetes...
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Posted by admin on Feb 28, 2026 in |
Background and Aim: Phenanthrene is an aromatic compound with three benzene rings forming the main structure. It represents the majority of polycyclic aromatic hydrocarbons found in the environment and is found in a variety of areas including, burnt smoky coal particles soil and sediment, diesel emissions, tobacco and food smoke. The aim of the study was to determine the effect of phenanthrene on oxidative stress markers in male Wistar rats. Methodology: Fifty healthy rats weighing between 100 and 180g were used for this study. The animals were randomly assigned into five groups of ten rats per group. Group A served as control and the animals were administered with 1ml of DMSO oil only orally for three weeks. Groups B animals were administered orally with 5mg/kg of phenanthrene dissolved in 9ml of DMSO oil and Group C animals were administered orally with 10mg/kg of phenanthrene dissolved in 13ml of DMSO oil for three weeks. Group D animals, had 180mg/kg of phenanthrene dissolved in 1ml of DMSO oil orally, once, while...
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Posted by admin on Feb 28, 2026 in |
This study investigated four medicinal plants Moringa oleifera leaves, Hippophae rhamnoides (Sea buckthorn) berries, Syzygium cumini seeds, and Psidium guajava leaves for their suitability in developing a polyherbal antidiabetic syrup. Hydroalcoholic extracts were prepared through maceration and yielded diverse phytochemical constituents, including flavonoids, alkaloids, saponins, glycosides, tannins, and phenols. Among the plants, Syzygium cumini exhibited the richest phytochemical profile, while Sea buckthorn uniquely contained terpenoids and steroids. Three syrup formulations were evaluated and found to possess acceptable physicochemical properties, with Formulation 2 demonstrating optimal viscosity, pH, and palatability. In-vitro antidiabetic analysis showed that all extracts inhibited α-amylase, while Syzygium cumini and Moringa oleifera demonstrated dual inhibition of α-amylase and α-glucosidase, though with higher IC₅₀ values than Acarbose. Overall, the results support the potential of these plants particularly Syzygium cumini for use in a synergistic polyherbal syrup aimed at managing diabetes through digestive enzyme inhibition. Further in-vivo and clinical investigations are recommended to confirm efficacy and...
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Posted by admin on Jan 31, 2025 in |
The review delves into the latest developments in dengue fever treatment, particularly focusing on emerging therapies such as vaccines and host-directed therapies (HDTs) designed to bolster the immune response to the virus. It outlines the progress in vaccine research, with a particular emphasis on the introduction of Dengvaxia, the first licensed dengue vaccine, and highlights ongoing efforts to develop more effective vaccines that offer broader protection across different serotypes of the virus. The review also underscores the importance of a holistic approach to managing dengue fever. It argues that alongside medical interventions, factors such as dietary considerations and community engagement are crucial in prevention strategies. It stresses the need for integrated public health initiatives that empower local communities to take proactive measures in controlling mosquito populations and reducing the risk of transmission. Furthermore, the review calls for sustained research efforts and collaboration across multiple sectors, including healthcare professionals, scientists, and policymakers. By fostering international cooperation, the hope is to develop innovative solutions that can effectively reduce the global burden...
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