Posted by admin on Sep 30, 2019 in |
Infectious diseases are one of the major problems in the world. After the discovery of penicillin, many classes of the antimicrobial agent were introduced and most infectious diseases were brought under control. However, the increased use of these antimicrobial agents in clinical practice was soon followed by the emergence of antibiotic resistance. Because of multiple drug resistance and adverse effects of these antimicrobial agents on the host, there is the need to discover and develop natural antimicrobials that are safe and with better therapeutic effects. Medicinal plants have been used as an alternative source of medicine to treat infectious diseases due to their rich antimicrobial activity. These Plants contain bioactive compounds such as quinines, phytoalexins, phenols, alkaloids, flavonoids, terpenoids, steroids, tannins, glucosinolates and pathogenesis-related proteins, which exert antimicrobial activity by different mechanisms, such as destruction of the cell membrane, inhibition of protein synthesis and enzymes impregnated on the cell membrane. There are various extracts of medicinal plants with minimum inhibitory concentration against pathogenic microorganisms that are safe and effective...
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Posted by admin on Sep 30, 2019 in |
Curcuma aromatica salisb, which belongs to the Zingiberaceae family, is a perennial herb. The rhizome of the plant consists of alkaloids, curcuminoids, flavonoids, tannins, and terpenoids which are reported to be the reasons for its various pharmacological properties. The extraction of compounds in different solvents shows that the plant contains neocurdione, curdione and germacrone as its major components. An extensive literature survey showed that the plant has anti-obesity, anti-acne, anti-cancerous, anti-tussive, anti-oxidant, larvacidal anti-inflammatory, anti-bacterial and wound healing properties. The rhizome extract of the plant is highly effective against many human pathogens as well as microorganisms causing food spoilage and foodborne diseases. The aim of this study is to review the phytochemical and pharmacological properties of Curcuma aromatica...
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Posted by admin on Aug 31, 2019 in |
Piper betel Linn. an important species of the Piperaceae family is an evergreen and perennial creeper, with glossy heart-shaped leaves that are magnificent reservoirs of phenolic compounds with anti-proliferative, anti-mutagenic, antibacterial and antioxidant properties. Phytochemical studies show that Piper betel contains a wide variety of biologically active compounds whose concentration depends on the variety of the plant species. Many research studies on Piper betel has reported that it contains important chemical constituents such as chavibetol, chavibetol acetate, caryophyllene, allylpyrocatechol diacetate, campene, chavibetol methyl ether, eugenol, a-Pinene, f-Pinene, u-Limonene, safrole, 1-8-cineol, and allylpyrocatechol monoacetate. These components are valued as a stimulant for its medicinal properties like anti-fungal, anti-nociceptive, anti-cancer, immunomodulatory, anti-halitosis, anti-diabetic, gastroprotective, anti-allergic, anti-fertility, anti-filarial, anti-larvicidal, wound healing and anti-dermatophytic. The present review is an attempt to highlight various traditional uses as well as pharmacological reports on Piper betel...
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Posted by admin on Jul 31, 2019 in |
Tinospora cordifolia (T. col.), a plant which has great significance in the Ayurvedic system of medicine, has been tested according to modern medical techniques for numerous therapeutic effects like immunomodulation, reducing tumor cells, purification of blood, reducing fatty lipids from body, reduction of glucose and increasing glucose tolerance in case of diabetes and increasing body weight. T. col has been used even during various rheumatic diseases like rheumatoid arthritis and has shown positive therapeutic effects. T. col. reduces the unwanted lipids. It enhances the humoral immune response. It also cleans out the immune complexes from the body. T. col. acts as an adaptogen. It has been reported to both increase and decrease activities of substances in the body, so as to normalize its functionality. It enhances immunity, but on the other hand, it inhibits autoimmunity. This paper is a review of the findings of the medical benefits of T. col., and combining all the information to propose that this plant may be used in the treatment of another rheumatic...
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Posted by admin on Jul 31, 2019 in |
Ocimum tenuiflorum Linn. commonly known as holy basil, tulsi is an aromatic perennial plant in the family Lamiaceae. It is native to the Indian subcontinent and cultivated plant throughout the Southeast Asian tropics, where the leaves, seeds ad stem of tulsi are used for valuable source of culinary and traditional medicinal uses. Indian material medica describes the use of the plants in a variety of ailments such as immunostimulatory effect, gastric antiulcer activity, diabetics mellitus, hyperlipidemia, wound healing effects, protective effect, chemopreventive activity, and blood pressure, etc. The present review aims to summarize up to date information on the ethnomedicinal, phytochemical and pharmacological activity. Until now, highly complex natural molecules have identified including fixed oils, essential oils, triterpenes, flavonoids, flavonoid glycosides, polysaccharides, phenolic glycoside, lignans, and norlignans. In addition to solvent extracts, these individual active compounds have been suggested for ethano-pharmacological activities. Although the results are promising in-vitro and in-vivo preclinical studies, clinical studies are insufficient; therefore, further investigation of each active compound need to be done to validate...
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