Posted by admin on Apr 23, 2016 in |
Over-harvesting of many traditional medicinal plants has become a threat to the country’s species diversity and has resulted in the endangerment of certain medicinal plant species. Shortly, many plant species may be unavailable for the use of industry due to over-exploitation. The present study outlines the concept of plant part substitution. The studies were carried out in Ailanthus excelsa to evaluate the possibilities of using small branches in place of stem bark which will help sustainable utilization. Stem bark and small branches of Ailanthus excelsa are compared by the physicochemical analysis, phytochemical analysis, total phenolic contents, total flavonoid contents and High-Performance Thin Layer Chromatography (HPTLC). Phytochemical analysis and HPTLC of n-hexane, ethyl acetate, and ethanol extracts showed many similarities which suggest that small branches may have nearly similar active potency like stem bark and may provide the base for further study to use small branches as a substitute of stem bark of Ailanthus excelsa. The study will be helpful in identification and quality control of Ailanthus excelsa and can...
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Posted by admin on Apr 23, 2016 in |
Protective effect of the probiotic combination of usnic acid and Lactobacillus casei in experimentally induced ulcer in rats was investigated. Rats inward usnic acid (100 mg/kg), L. casei (10-8 con.), usnic acid (100 mg/kg) + L. casei (10-8 con.), and omeprazole (30 mg/kg) twice daily for 5 days for prevention against aspirin (ASP), ethanol (EtOH), cold restraint stress (CRS) and pylorus ligation-induced ulcer (PL). The results of the present study showed the first time that the usnic acid (100 mg/kg) + L. casei (10-8 con.) as probiotic combination significantly inhibited the ulcer index in ASP, EtOH, CRS and PL to 3.4 ± 0.12, 6.3 ± 1.8, 3.4 ± 0.8 and 4.3 ± 0.9 (p<0.001) respectively, as compared to control group (19.2 ± 1.6, 22.5 ± 6.3, 24.2 ± 3.2, 14.2 ± 2.7). Besides usnic acid (100 mg/kg) + L. casei (10-8 con.) offered protection (72%, p<0.001) against ethanol-induced depletion of gastric wall mucus. The usnic acid (100 mg/kg) + L. casei (10-8 con.) showed significant inhibition of lipid peroxidation...
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Posted by admin on Apr 23, 2016 in |
Cardaria draba commonly known as whitetop or hoary cress is a perennial herb that is native to Eastern Europe and eastern Asia, including Iran. In this study, the effects of alcoholic extract of Cardaria draba (25, 50 and 100 mg/kg) via oral gavage for 2 weeks alone and on scopolamine (1 mg /kg/d, 4 days, i.p.) – zinc chloride (75 mg/kg/d, 2 weeks oral gavage) – and sodium metavanadate (22.5 mg/kg/d, 2 weeks oral gavage) – induced avoidance memory retention alterations were investigated in the step-through passive avoidance task. Zinc chloride and scopolamine were dissolved in saline and sodium metavanadate were dissolved in animal’s drinking water. At the end of each part of studies, animals were trained for one day in a step-through task. The avoidance memory retention alterations were evaluated 24 h, 48 h, 96 h and 168 h later to the training session. Zinc chloride and sodium metavanadate oral gavage for 2 weeks decreased latencies compared to control animals. Also, four days intra-peritoneal injection of scopolamine decreased...
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Posted by admin on Mar 13, 2016 in |
Trianthema decandra Linn., belongs to family Aizoaceae, commonly known as “Punarnavi” in Sanskrit, “Gadabandi” in Hindi, and “Vellai sharuni” in Tamil. This plant is globally distributed tropical and subtropical regions. In India, it grows in dry-soil lands. It has been known since ancient times for curative properties and has been utilized for treatment of various ailments such as burns and wounds. The roots are aperients and said to be useful in hepatitis, asthma, and suppression of the menses. A decoction of the root-bark is given as an aperients. The juice of the leaves dropped into the nostrils relieves one-sided headache. 1 In the present investigation, the detailed Pharmacognostic study of Trianthema decandra root is carried out to lay down the standards, which could be useful in future Forensic identification of unknown plant material. Results: The study includes macroscopic, microscopic, preliminary phytochemical screening and physicochemical evaluation. The objective this was to characterize the unknown plant material. Conclusion: In recent years there has been a rapid increase in the standardization of...
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Posted by admin on Mar 13, 2016 in |
Cinnamon is one of the best-known spices used as herbal medicine. Cinnamaldehyde is the most important constituents of cinnamon. The present study was aimed to evaluate the analgesic activity of Cinnamaldehyde per se and its interaction with diclofenac sodium and pentazocine in Swiss albino mice. Healthy mice of either sex weighing 20-30 grams were divided into 6 groups of 6 animals each. Peripheral analgesic activity was evaluated by acetic acid induced writhing test, and central analgesic activity was studied using Eddy’s hot plate method. Cinnamaldehyde (100 and 200 mg/kg) and its combination (Cinnamaldehyde 100 + 2.5 mg/kg standard drug), diclofenac sodium (2.5 and 5 mg/kg) and pentazocine (2.5 and 5 mg/kg) were given orally. Acetic acid induced writhing model showed that diclofenac sodium at doses of 2.5 and 5 mg/kg reduces writhing 44% and 66% respectively as compared to control when administered alone. Cinnamaldehyde at 100 and 200 mg/kg showed dose-dependent decrease in writhes 54% and 81%, but when Cinnamaldehyde (100 mg/kg) was co-administered with diclofenac sodium (2.5mg/kg) showed...
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