Posted by admin on Oct 13, 2017 in |
Diabetes mellitus is one of the widespread and severe metabolic disorders in humans all over the world. It is initially characterized by a loss of glucose homeostasis resulting from defects in insulin secretion, insulin action or both resulting in impaired glucose metabolism and other energy-yielding fuels such as lipids and proteins. The association of hyperglycemia with altered lipid parameters presents a major risk for all cardiovascular diseases. In recent years, there has been an increased inclination towards herbal drugs due to the trend towards the natural sources and healthy lifestyle. The present study was designed to evaluate the potential antihyperlipidemic efficacy of Citrullus colocynthis roots in streptozotocin (STZ) induced diabetic rats. Diabetes was induced by giving streptozotocin (35-50mg/kg) intraperitoneally. The aqueous and ethanolic root extracts of Citrullus colocynthis (AECC and EECC) were administered at a dose of 100, 200, 300 mg/kg orally. Metformin was given as a standard drug at a dose of 50mg/kg orally. The fasting and postprandial blood glucose levels were estimated by the glucose oxidase method....
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Posted by admin on Oct 13, 2017 in |
Green synthesis is a cheaper, clean, nontoxic route for the synthesis of large scale nanoparticles without the use of high energy, pressure, temperature, and toxic chemicals. With the help of microbial enzyme and plant extract nanoparticles are easily synthesized by utilizing their antioxidant and reducing properties. In the present study, biosynthesis of silver and gold nanoparticles by utilizing Alhagi maurorum stem aqueous extract reducing capabilities was successfully done. Nanoparticles synthesized were characterized with the help of UV – VIS spectroscopy, Transmission Electron Microscopy (TEM) and Fourier Transform Infra-Red spectroscopy (FTIR). UV – VIS spectroscopic analysis showed absorption maxima at 450 nm and 540 nm for silver (AgNP) and gold nanoparticles (AuNP) respectively. TEM study revealed that the silver and gold nanoparticles synthesized were in the range of 26-40 nm and possesses a crystalline structure having a nearly spherical shape. FTIR spectra of both AgNP and AuNP also confirmed the synthesis of nanoparticles and involvement of various reducing agent of plant extract. No change in the intensity of the AgNP...
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Posted by admin on Sep 8, 2017 in |
A simple TLC method has been developed for the simultaneous quantification of bergenin using HPTLC plate precoated with silica gel 60 F254. The method was developed in toluene: ethyl acetate: acetone (2:4:4 v/v) toluene: ethyl acetate: formic acid (4:6:1, v/v) and validated in terms of precision, repeatability, and accuracy. The isolated compounds were characterized using spectroanalytical techniques and found to be bergenin. The in-vitro antioxidant activity of the isolated compound was determined. For the antioxidant potential, two standard analytical protocols, namely, DPPH radical scavenging activity (RSA) and ferric reducing antioxidant power were adopted. The results showed that the compound was found to be a more potent...
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Posted by admin on Sep 8, 2017 in |
This study evaluated the scientific basis for the traditional use of Aegiceras corniculatum (Myrsinaceae) stem extract as an anthelmintic agent. The study design was an investigation of the traditional anthelmintic medicinal plant Aegiceras corniculatum using in-vitro anthelmintic properties of four extracts of the plant were evaluated using earthworms. The earthworm (Pheretima posthuma) resembles both anatomically and physiologically to the intestinal roundworm parasites of human beings. The four crude stem extracts of Aegiceras corniculatum were petroleum ether extract (50 & 100 mg/ml), chloroform extract (50 & 100 mg/ml), methanol extract (50 & 100 mg/ml) and aqueous extract (50 & 100 mg/ml). The paralysis time of petroleum ether extract (96 ± 6.33 & 76 ± 2.31), chloroform extract (116 ± 4.36 & 92 ± 7.50), ethanol extract (62 ± 3.20 & 34 ± 3.52) and aqueous extract (200 ± 2.22 & 180 ± 3.19) were compared to the standard drug Albendazole suspension 100mg / 5ml (5 ± 1.00). The results showed that the four extracts produced dose-dependent and significant anthelmintic activities....
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Posted by admin on Sep 8, 2017 in |
The present study was conducted to investigate the color strength (K/S), colorfastness, antibacterial and antioxidant properties of silk using fabric Cichorium intybus root extract as a natural dye. Comparative results of color fastness (fastness to wash, rub, light and perspiration) and colorimetric properties (CIELab and K/S values) of dyed silk samples were studied to quantify the effect of mordants and mordanting method. Alum and myrobalan were used as mordants. Three methods of mordanting techniques were used (pre, meta and post-mordanting). The samples showed acceptable color strength and colorfastness values. The antibacterial activity of the dyed samples with and without mordants was tested against common pathogens Escherichia coli and Staphylococcus aureus. The antioxidant property of the dyed fabric was analyzed by DPPH method. Cichorium intybus proved to be very effective in inhibiting microbial growth. The results of DPPH assay were positive for all the samples. The dyeing of silk fabric with Cichorium intybus root extract provided a multifunctional textile material with both antioxidant and antibacterial...
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