Posted by admin on Aug 24, 2016 in |
Plant oils have been used for a variety of purposes for many thousands of years. In particular, the anti-microbial & anti-fungal activity of plant extracts and oils have formed the basis of many applications. Since, Aspergillus niger contamination in leather and leather apparels reduces the export value considerably, demand an appropriate solution. The present study emphasizes the anti-Aspergillus potential of an essential oil and microsphere formulation in combating the A. niger growth in finished leather. A. niger ATCC 16888 strain was chosen for the present study. Both well diffusion and broth dilution methods are used. Mode of action and microsphere formulation and its impact on leather studied using standard protocols. Essential oil (EO) of Acorus calamus L. exhibited appreciable Anti-Aspergillus potency compared to untreated control and standard drugs (Itraconazole & Voriconazole). The oil contains components in addition to asarone. The damage in the plasma membrane and reduction in ergosterol content authenticate the antifungal action EO. The new microsphere formulation of an essential oil appreciably prevent the growth of A....
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Posted by admin on Jul 29, 2016 in |
Aim of the study: This study aimed to investigate the antidiabetic activity of ethanolic leaves extracts of Bauhinia galpinii Linn. alloxan, induced diabetic in rats. Materials & methods: The adult male albino rats of weight 180-240 gm were selected for the study. The Dose of 100 mg/kg, 250 mg/kg and 500 mg/kg of ethanol extract was selected for the test. All the doses were given orally after making an emulsion in the vehicle, i.e., 1% acacia gum and the standard drug, i.e., glimepiride was given orally (10 mg/kg) in the vehicle. Diabetes mellitus was induced by administering an intraperitoneal injection of alloxan monohydrate 120 mg/kg to the overnight fasted rats. A blood sample was collected from tail nipping, and an automatic electronic glucometer determined glucose level. Ethanolic extract of Bauhinia galpinii Linn. leaves were subjected to anti-diabetic activity in rats where alloxan monohydrate (120 mg/kg b.w., i.p.) used as the diabetogenic agent. A marked rise in fasting blood glucose level observed in diabetic control compared to normal control rats....
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Posted by admin on Jul 29, 2016 in |
About 4 extracts (hexane, acetone, ethanol, and methanol extraction) from the seeds of Centratherum anthelminticum was extracted. Gas Chromatography-Mass Spectroscopy characterized ethanol extract. Seven constituents from 9 peaks were identified. 2-Oxo-pentanoic acid and hexadecanoic acid are as the major constituents, and the minor constituents like Henicosanoic acid, 26-Phenoxy-hexacosanoic methanoate, Hexadecanoic acid methyl ester, dotriacontanoic acid ethyl ester, nonadec-3-ene, icosa-2,5, diene, and tetratriacontane were identified. The antimicrobial activity of the different extract was tested against human and plant pathogenic bacteria. Ethanol extract showed a significant role in inhibiting almost all tested pathogenic organisms and antitubercular activities at various...
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Posted by admin on Jul 29, 2016 in |
To evaluate the possible antifertility effect of 50% ethanolic extract of C. bonducella seeds in male rats. Adult, healthy, male Wistar rats were randomly selected and divided into three groups each having 7 rats. Group, I rats were treated with vehicle only and served as control. While group II and Group III rats were orally treated with C. bonducella extract at 200 mg and 400 mg/kg body weight/day, respectively for 60 days. The result of the present study indicated that there was a significant decrease in the relative weights of testes and accessory sex glands in treated rats. The density, motility, and viability of spermatozoa obtained from cauda epididymis were significantly (P<0.01 at 200 mg and P<0.001 at 400 mg) diminished in both treated groups as compared to control group. The serum testosterone level also showed significant (P<0.05 at 200 mg and P<0.01 at 400 mg) decline. The fertility rate and litter size decreased significantly in extract treated rats. Extract treatment also induced alteration in the biochemical milieu of...
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Posted by admin on Jul 29, 2016 in |
Prophet Mohammed calls Nigella sativa seed as a medicine of blessings. Nigella sativa is an herbaceous plant and cultivated in the Middle East, South East Asia and some part of Europe. Nigella sativa seed has been in use in the Middle East, South East Asia and some part of Europe over 2000 years. Until date lot of research, studies are conducted to prove the therapeutic utility of Nigella sativa seeds. In these various studies, Nigella sativa seeds and its derivative showed therapeutic activity against allergy, cough, and diabetes, different types of cancer and skin infections. It is one of the widely used spices in the Middle East, South East Asia and some part of the Europe Nigella sativa seed is intensively studied for its chemical composition. It is reported to contain Thymoquinone, Nigellimine-N-oxide, Nigellicine, Nigellidine, Nigellone, Dithymoquinone, Thymohydroquinone, Thymol, Arvacrol, 6-methoxy-coumarin, 7-hydroxycoumarin, Oxy-coumarin, Alpha-hedrin, Steryl-glucoside, Tannins, Flavinoids, Essential fatty acids, Essential amino acids, Ascorbic Acid, Iron and Calcium. The presence of these natural actives makes Nigella sativa seed as...
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