Posted by admin on May 30, 2017 in |
The present work was executed to evaluate the anti-diabetic potency of a polyherbal preparation. The objective of this study is to induce experimental diabetes mellitus using streptozotocin in normal Albino wistar rats and study the anti-diabetic activity of polyherbal formulation by comparison of changes in levels of glucose between normal and diabetic rats. The effect of methanol extract of polyherbal preparation containing aerial parts of Schrebera swietenoides, roots of Barleria montana and aerial parts of Rotula aquatica was investigated in normal and streptozotocin-induced diabetic rats. The lowest blood glucose levels were observed at 4 and 8th h after the oral administration of 150 and 300 mg/kg b.w polyherbal formulation. The blood glucose levels at 24 h after the oral administration of 150 and 300 mg/kg b.w. of the polyherbal formulation was significantly lowered the blood glucose...
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Posted by admin on May 30, 2017 in |
Mangiferin content in aqueous extracts of 30 varieties of Mangifera indica leaves collected from Gujarat state of Western India has been estimated during this study, using a simple reverse phase HPLC-DAD analysis method. The proposed method has been validated according to ICH guidelines in terms of linearity, accuracy, intraday and interday precision, limit of detection and limit of quantitation. The calibration graph was found to be linear over a concentration range of 20-120 µg/mL, with a regression coefficient of 0.9943. Determination of accuracy by standard addition method at three different concentration levels returned a mean recovery value of 97.64%. Average intraday and interday precision values were found to be less than...
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Posted by admin on May 30, 2017 in |
Objective: The study was designed to explore the antibacterial, antifungal and antioxidant potential of Jatropha curcas Linn. (J. curcas) stem bark extract. Materials and Methods: The chemotherapeutic action was measured in the crude extract using agar well diffusion method. The antibacterial and antifungal activities of different extracts were tested against two gram-positive and nine gram negative human pathogenic bacteria using agar well diffusion method. Area of the reticence of crude extracts was matched with that of various antibiotics like ampicillin, streptomycin for antibacterial property and fluconazole for antifungal activity. The antioxidant and free radical scavenging activities of different extracts of the Jatropha curcas were also investigated against 2,2 Diphenyl –1- picrylhydrazyl (DPPH), 2,2, Azion-bis- (3- ethylbenzothia-zoline-96- sulphonic acid) (ABTS), superoxide anion (O-2) and nitric oxide (NO) using spectroscopic absorption methods. The data were statistically analyzed by ANOVA, arranged in completely randomized design (CRD) in the factorial arrangement having four replications. Results: The average inhibition zone for methanol extract (25.31mm) was establish to be extra valuable than the average inhibition...
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Posted by admin on May 30, 2017 in |
In this study antioxidant activity was performed by DPPH (1,1 diphenyl-2-picrylhydrazyl) radical scavenging method for Tribulus terrestris L. whole plant methanolic extraction fractionation with toluene and n-butanol in succession. The obtained fractions were concentrated under reduced pressure to yield corresponding antioxidant activity. The IC50 concentration for the standard, ascorbic acid and BF-TTME was found to be 0.085 and 4.5 μg/ml...
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Posted by admin on May 30, 2017 in |
The present study was designed to judge the in vitro antibacterial activity and comparison of Ocimum basilicum and Cymbopogon martinii. From the folklore claim and ethnobotanical review, the plant Ocimum basilicum and Cymbopogon martinii leaves have been found to contain terpenes and terpenoids i.e. essential oil, and the plants are used in indigenous system of medicine for the treatment of bacterial infections. It is generally considered that compounds produced naturally rather than synthetically, will be biodegraded more easily and be therefore environmentally more acceptable. Thus, natural drugs which are used to treat various diseases antibacterial, antiviral, antifungal, antioxidants, cytotoxic and nutrients gained importance in the recent years, and their use and positive image among consumers are spreading. In recent years multiple drug resistance in both human and plant pathogenic microorganisms have been developed due to the indiscriminate use of commercial antimicrobial drugs commonly used in the treatment of infectious diseases. To find new therapeutic agents, plants that have antibacterial (antimicrobial) activity have attracted the attention of researchers. The antibacterial...
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