Posted by admin on Jun 30, 2018 in |
Portulaca quadrifida Linn. (Portulacaceae) is commonly known as a chicken weed in English. In the traditional system, it is used to treat rheumatism and gynecological diseases, urinary tract infections, worm diseases, dysentery and dermatitis. To assess the cytotoxic potential of hydroalcoholic extract of P. quadrifida leaves using brine shrimp assay. Potassium dichromate was considered a standard reference drug. The concentrations of 10, 100, 1000 μg/ml were used in the experiment. The mature shrimps were taken, and it was treated with the extract and the standard in the respective concentrations. LC50 value was calculated for both standard and extract, and the probit analysis was made by using SPSS software. From the probit analysis, the cytotoxicity of the extract was determined by comparing it with the standard. The graph was plotted for both the standard and the extract; the extract was found to be non-...
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Posted by admin on Jun 2, 2018 in |
Unprecedented growth in popularity of complementary medicines raised concerns about their quality and safety. So, there is a need to develop methods for their sensitive, specific and accurate analysis. Authenticity and similarity of medicinal nutrients and strict procedures of material handling are significant features to maintain the quality of herbal preparations. Genome-based methods to authenticate these plants revolutionized the authentication process. Developing DNA molecular markers by sequencing a standard zone of the DNA is the best technique to identify the adulterants as well as to authenticate the required species of medicinal plants. Application of molecular biological technique serves as one of the very consistent systems for authentication of natural herbal materials. The progress of authentic analytical methods is a major challenge to scientists as natural products are optimized as drug-like molecules. Current work is based on the use of PCR technique for authentication of Glycyrrhiza glabra L. standard crude root and in polyherbal formulations i.e., Hamdard’s Joshanda, Marhaba’s Joshanda, GNC Herbal supplement and Joshaba Sadar (Chest Tea) available in...
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Posted by admin on Jun 2, 2018 in |
Objective: To study detailed pharmacognostic characters of the stem of Nyctanthes arbor-tristis (Oleaceae), along with their physicochemical parameters, fluorescence analysis, and phytochemical screening. Methods: The pharmacognostic characters were determined in terms of macroscopy, microscopy, powder microscopy, physicochemical analysis, fluorescence analysis and preliminary phytochemical investigation of the plant stem. Results: The microscopic study shows the general characteristic of the stem. Physico-chemical investigation shows the total ash, acid insoluble ash, water-soluble ash were 8.69 ± 0.17% w/w, 0.21 ± 0.11% w/w, and 3.92 ± 0.05% w/w respectively. Phytochemical analysis revealed the presence of various phytochemical groups like alkaloids, glycosides, steroids, phenolic, tannins constituents. Conclusion: It can be concluded that the established pharmacognostic profile of Nyctanthes arbor-tristis stem will help develop pharmacopoeial standards for correct identification and quality...
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Posted by admin on Jun 2, 2018 in |
The free radical scavenging activity of ethanolic root extract of Aporosa lindleyana (EREAL) was evaluated in-vitro with the spectrophotometric method based on the inhibition of hydroxyl radical, the reduction of stable DPPH free radical, inhibition of superoxide anion radical, total antioxidant activity and reducing power. Preliminary phytochemical screening showed the presence of phenolic compounds and flavonoids. EREAL showed significant activities in all free radical scavenging assays compared to standard antioxidants such as ascorbic acid, butylated hydroxyl toluene and vitamin E. In DPPH scavenging assay the IC50 value of EREAL was 215.51 µg/mL, while vitamin E had 299.11 µg/mL. Furthermore, EREAL showed good free radical scavenging activity on reducing power, superoxide anion radical activity, total antioxidant activity, hydroxyl radical activity and had good reducing...
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Posted by admin on Jun 2, 2018 in |
The influence of roots and leaf extracts of Jasminum grandiflorum was studied for its wound healing activity using the excision wound model. The roots and leaves of Jasminum grandiflorum were extracted with alcohol 90%, were subjected to phytochemical investigation. The root and leaf extracts were screened for wound healing activity. The animals were divided into four groups in excision wound model; controls were treated with normal saline, standard were treated with betadine and the experimental groups were treated with root and leaf extracts of Jasminum grandiflorum till complete epithelisation. The leaf extract treated wounds were found to epithelise faster as compared to the control group. Leaf extract treated rats exhibited 61.346% reduction in the wound area when compared to the control of 55.72%. The demonstration of an increased rate of wound contraction findings suggests the use of Jasminum grandiflorum leaf extract in the management of wound healing....
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