Posted by admin on Jun 30, 2018 in |
Trichosanthes cucumerina var. cucumerina Linn. is an annual monoecious climber. Trichosanthes cucumerina var. cucumerina Linn. mainly distributed in Asian countries like India, Sri Lanka, Bangladesh, Burma, Malaysia, and Australia. Trichosanthes cucumerina var. cucumerina is a wild variant (Cucurbitaceae) the major active components are triterpenoids, saponins, and cucurbitacins; chemical constituents like flavonoids, carotenoids and phenolic acids are also present. Trichosanthes cucumerina var. cucumerina is used in the treatment of headache, alopecia, fever, abdominal tumors, bilious, boils, acute colic, diarrhea, haematuria, and skin allergy, etc. Trichosanthes cucumerina is used as an abortifacient, vermifuge, refrigerant, purgative, malaria, laxative, hem agglutinant, emetic, cathartic, bronchitis and anthelmintic. The present study involves the pharmacognostical and phytochemical studies of the plant. The transverse section was taken for the microscopical studies. Powder microscopy shows the presence of annular, spiral, cylindrical, tubular and thick-walled xylem vessels. Different physicochemical evaluation ash value, extractive value, fluorescence analysis, etc, were performed. Phytochemical evaluation is performed for the ethanolic extract of leaves presence of alkaloids; flavanoids, glycosides, phenols, etc. are...
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Posted by admin on Jun 30, 2018 in |
The mulberry has been widely cultivated to feed silkworms. The leaves of mulberry have been used in traditional medicine as an analgesic, antitussive, cathartic, diuretic. In this study, we have isolated three compounds (LC1-3) by chromatographic methods from the mulberry leaves (Morus alba L.) collected in Thai Nguyen province, Vietnam. These compounds were identified as Kaempferol-3, 7-di-O-α-L-rhamnopyranoside (LC1), 7, 4’- dihydroxy-5, 3’- dimethoxyflavone (LC2), (S)-5, 5’, 7-trihydroxy-2’, 4’-dimethoxy-6-methylflavanone (LC3). Their structures were elucidated by spectroscopic methods, including MS and NMR. Compound LC3 was isolated from mulberry leaves for the first time. These compounds were evaluated the tyrosinase inhibitory activity in-vitro. Our data showed that compound LC3 has potential tyrosinase inhibitory effects with IC50 values of 15.48 ± 2.96...
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Posted by admin on Jun 30, 2018 in |
Present communication deals with the pharma-cognostical standardization on the roots of Agnimantha (Premna serratifolia L. (syn. P. integrifolia L.) belong to the family Verbenaceae. It is an important medicinal plant used in many Ayurvedic formulations. According to Ayurveda the roots and leaves are the most useful parts of the plant. It is one among the Dashamula. Macro, microscopical and physicochemical studies were carried out as per the latest Ayurvedic Pharmacopoeia of India, part-1, volume-8 protocols to establish its Pharmacognostical standards. Studies revealed the presence of abundant, simple to compound starch grains with prominent hilum in the center, cork cells filled with yellowish brown pigmented cells, starch grains in the medullary rays, abundant xylem vessels with bordered pits and tracheids with pits, prism-shaped crystals in the cortex region. Phytochemical studies showed the presence of carbohydrates, alkaloids, phenols, tannins,...
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Posted by admin on Jun 30, 2018 in |
Curcuma albiflora Thw. is an important anti-inflammatory medicinal plant, which is used in Sri Lankan Traditional Medicine. The plant is endemic to Sri Lanka and unexplored. Therefore it is necessary to conduct a proper systematic study to establish a chemical profile of C. albiflora. Therefore, the current study was conducted GC-MS study on various extracts of C. albiflora. The whole plant parts of the plant C. albiflora were collected from June to October in the flowering season at Sabaragamuwa province, Sri Lanka. Samples were authenticated by National Herbarium, Peradeniya. Hydro-distillation by Clevenger’s apparatus and continuous extraction by Soxhlet apparatus were carried out on various solvents (petroleum ether, acetone, and methanol). GC-MS analyses were performed on various extracts (water, petroleum ether, acetone, and methanol) of C. albiflora. Retention index was calculated of each compound based on standard alkane chromatogram. The whole plant of C. albiflora essential oil consisted mainly of α-pinene (14.51%), caryophyllene oxide (9.35%), alcanfor (5.12%), aromadendrene oxide-I (4.81%), α-famesene (4.01%) and camphene (3.64%). While petroleum ether extract of...
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Posted by admin on Jun 30, 2018 in |
Honey is commonly used by the indigenous population in Brazil due to its large variety of physiological properties such as ulcers and dermatitis healing. The goal of this paper is to select and to test different types of Brazilian honey to be used associated with Aloe vera as an accessible wound treatment. Three types of honey were analyzed: two produced by Tetragonisca angustula in different regions of Brazil and one honey produced by Apis mellifera scutellata, associated with both water and Aloe vera. Quantitative assays, where bacterial growth curve was analyzed by optical density, were performed to test the antimicrobial activity of the samples. From the results obtained, we observed that the three types of honey studied presented a satisfactory antimicrobial activity. The association between honey and Aloe vera, besides demonstrating better antimicrobial action than each compound itself, it demonstrated better effectiveness against Enterobacteriaceae species (E. coli and S....
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