Posted by admin on Jul 31, 2020 in |
Nowadays, the use of essential oils as alternative therapies has gained worldwide concern, owing to their various biological activities. Considerable attention has been devoted to essential oil, which is widely used for its important properties, including antimicrobial, anti-inflammatory, antispasmodic, cytoprotective, hepatoprotective, with strong antioxidant actions. Eucalyptol is an essential oil present in large amounts in a variety of plants, which is frequently used in the manufacture of cosmetics, to increase percutaneous penetration of drugs, as a nasal decongestant and anti-cough agent, and in aromatherapy. GC analysis of the essential oil was carried out on the Agilent 7820A system with a mass detector (MS) and a HP-5 MS column (30 m × 0.25 mm, 0.25 μm film thickness). Nineteen essential chemical constituents were identified based on GC-MS in Eucalyptus oil supplied from the pharmacy. The main constituents of Eucalyptus oil are eucalyptol (76.81%), γ -terpinene (7.75), α-pinene (6.62), and α-terpineol (1.44%). These four components account for 92.6% of the total relative content of the Eucalyptol oil. This research also demonstrated...
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Posted by admin on Jul 31, 2020 in |
Acne is a skin-related condition entailing many psychological complications. Although several medications have been developed, natural remedies attracted more attention because of the less side effects and multifunctional. The objective of this study was to prepare and evaluate the anti-acne effects of a pharmaceutical gel containing herbal extracts, including Lawsonia inermis and Matricaria chamomilla. The total phenolics of extracts were determined with the Folin-Ciocalteu method. Using Hydroxypropyl methylcellulose (HPMC), carboxymethyl cellulose (CMC) and propylene glycol (PEG), the pharmaceutical gel was formulated and the physical properties of the formulation were specified at 37 ± 2 °C. The release of the active ingredients from the optimum formulation was investigated using Franz cell device. The results showed that the optimum formulation was stable at least for 3 months. The total phenol content of the aqueous extract of Henna leaves, hydroalcoholic extract of chamomile flowers, and the optimum formulation was 57.8 mg/g ex, 181.08 mg/g and 202.75 mg/g, respectively. Nearly 80 % of the phenolic compounds in the optimum formulation were released over...
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Posted by admin on Jun 30, 2020 in |
Context: Dhamaso, botanically known as a Fagonia Arabica is an important plant in Ayurveda and in folklore medicine, but little is known about its pharmacognostic evaluation. Objectives: In the present investigation, the detailed pharmacognostic study of Fagonia arabica stem is carried out to lay down the standards which could be useful in future experimental studies. Materials & Methods: The present study included macroscopy, microscopy, preliminary phytochemical screening, and physicochemical evaluation. Results: Macroscopy reveals the organoleptic properties of the stem, and the microscopic study shows the presence uni-seriate to tri-seriate medullary rays and brownish matter in pith region as diagnostic characters. Water-soluble ash value is more than acid insoluble ash indicates that the acid-insoluble siliceous matter was less than that of water-soluble ash. The preliminary phytochemical investigations indicate the presence of glycosides, flavonoids, saponins, sterols, carbohydrates, amino acids,...
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Posted by admin on Jun 30, 2020 in |
Spinach is a leafy green flowering plant. The leaves are a common edible vegetable consumed by fresh leaves. The bioactive components present in the Spinach oleracea plant leaves are known to be responsible for its medicinal properties. The present study was undertaken to compare the effect of different extraction solvents to extract the active components like carbohydrates, tannin, flavonoid, phenol, carbohydrate from the dried leaves of Spinach oleracea plant. The extraction solvents used were Ethyl acetate, Petroleum ether and Methanol. Phytochemical analysis, total flavonoid concentration, total phenol concentration and antioxidant activity have been identified to compare the efficiency of different extraction solvents. The results shows that using methanol as an extraction solvent works best for the extraction of various active phytochemicals, the total flavonoid and phenols concentration and the antoxidant activity showed the effective scavenging activity. This is the report that directly compares the three extraction solvents for the extraction of active components from the Spinach oleracea leaves and shows that method should be the solvent of...
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Posted by admin on Jun 30, 2020 in |
The present work has been done with an objective to analyze the crude drug parametrs responsible for tenable antioxidant effect of leaf, stem and root of Glycosmis pentaphylla (Retz.) DC. Fresh leaf, stem and root of Glycosmis pentaphylla were extracted with ethanol (EEGPle, EEGPst, EEGPro). The antioxidant profiling was done through different methods like 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging assay, 2,2-azino-bis-3-ethyl benzothiazoline acid (ABTS) free radical scavenging assay and nitric oxide (NO) free radical scavenging assay. Crude drug parameters were focussed mainly on micrometric properties so as to determine the flow properties when consumed for medicinal purposes. A significant antioxidant activity was revealed by the EEGPle [EC50: (29.04±0.008) µg/mL], compared to EEGPst and EEGPro in DPPH assay. The ranking order for ABTS was EEGPle > EEGPst > EEGPro. The EC50 value of NO of the EEGPle, EEGPst and EEGPro were (263.14±0.05) µg/mL, (312.62±0.07) µg/mL and (384.62±0.006)µg/mL respectively. Quantity of TFC and TPC were highest in EEGPle (112.96±3.89 mg QRE/g and 96.6±1.08 mg GAE/g extract) rather than EEGPst and EEGPro...
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