Posted by admin on Nov 30, 2025 in |
Mollugo pentaphylla L. (Molluginaceae), commonly known as carpetweed, has tremendous medicinal importance. Although the plant has been scientifically evaluated for its various biological activities but no work has not been carried out till date on comparative pharmacognostic characterization of the in-vivo plant and leaf callus. This study aims to investigate the comparative pharmacognostic and physicochemical standards for aerial parts and leaf callus of M. pentaphylla. The measures taken were macroscopic, organoleptic study, anatomy, powder microscopy, ash values, loss on drying, fluorescence analysis and extractive yield. This is the first study providing complete pharmacognostic profile of M. pentaphylla and hence will be useful for identification and authentication of the species for future...
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Posted by admin on Nov 30, 2025 in |
Medicinal plants play a vital role in addressing health problems, particularly in Africa, where they often constitute the primary therapeutic resource. Encouraged by the WHO, which recommends their integration into health systems, their use nevertheless requires rigorous control based on identification. In Côte d’Ivoire, among the most widely used botanical families are the Fabaceae, renowned for the diversity of their species with pharmacological properties. This study presents, a micrographic and chemical analysis of three plants from this family: Abrus precatorius, Bafia nitida, and Desmodium adscendens. The analyses performed included micrographic examination of leaf powders, phytochemical screening of hydroethanolic extracts, using thin-layer chromatography, and chemical analysis by HPLC-ESI(+)-Q/TOF. Microscopic analysis allowed us to identify the characteristic elements. Chemical analysis revealed the presence of several groups of secondary metabolites (alkaloids, flavonoids, quinones, tannins, sterols, terpenes, and polyphenols), confirming the potential of these plants as sources of bioactive molecules and highlighting the importance of their valorization and integration into healthcare...
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Posted by admin on Nov 30, 2025 in |
Irvingia gabonensis is a medicinal plant valued in African traditional medicine for its diverse therapeutic uses. This study focused on the ethyl acetate extract of its stem bark to isolate and identify its major bioactive constituent using modern chromatographic and spectroscopic techniques. Extraction of the powdered stem bark with ethyl acetate produced a 5.30% yield. Thin-layer chromatography (TLC) suggested the presence of several phytochemical components, and subsequent column chromatography led to the isolation of a prominent compound labeled TSM 01. TLC analysis confirmed its purity by showing a single, well-defined spot when sprayed with visualizing agents. The structure of TSM 01 was elucidated using a combination of Fourier Transform Infrared (FTIR), Proton and Carbon-13 Nuclear Magnetic Resonance (¹H-NMR and ¹³C-NMR), Gas Chromatography–Mass Spectrometry (GC–MS), and Liquid Chromatography–Mass Spectrometry (LC–MS). The FTIR spectrum showed characteristic peaks for hydroxyl and carbonyl functional groups, while NMR spectra revealed features typical of a symmetrical aromatic compound. The GC–MS and LC–MS data both displayed a molecular ion peak at m/z 302, consistent with a...
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Posted by admin on Nov 30, 2025 in |
The antihelmintic activity of Nigella sativa (family: Ranunculaceae), Lawsonia inermis (family: Lythraceae) and Syzygium cumini (Family: Myrtaceae) was studied against adult earthworms (Pheretima posthuma). The extract showed anthelmintic activity at the doses of 25 mg/ml, 50 mg/ml, and 100 mg/ml, although the reference standard used was albendazole (10 mg/ml). But the 100 mg/ml had the higher strong anthelmintic effect. Nigella sativa, Lawsonia inermis and Syzygium cumini caused paralysis and death of the earthworms at this concentration in about 7 and 37, 25 and 55 and 61 and 101 min, respectively. However, the extract of Nigella sativa at 100 mg/ml induced paralysis and death at about 7 and 37 min,...
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Posted by admin on Oct 31, 2025 in |
The present study indicates that the development of sunscreen by incorporating natural ingredients obtained from Phyllanthus emblica results in overcoming the side effects of chemically synthetic formulations. The Indian gooseberry, Phyllanthus emblica Linn, is a deciduous tree of the Euphorbiaceae family. The fruit of P. emblica is most widely used herbal drugs in Ayurvedic and Unani systems of medicine. Its chemical constituents include tannin (emblicanin A and B), phenol (gallic acid, ellagic acid), vitamins (ascorbic acid, niacin, thiamine, riboflavin), flavonoids (rutin, quercetin, kaempferol), and alkaloids (phyllantin, phyllembein), among others. Major formulations of Phyllanthus emblica, such as powder, oils, and candy, containing quercetin and emblicanin constituents, show biological potentials including antioxidant, hepatoprotective, anti-inflammatory, and neuroprotective properties, among others. Sunscreens were the best alternatives to prevent sunburns or to protect the skin from the damaging effects of UV rays. The herbal ingredients in the formulation were safe to use as they contain natural substances having fewer side effects, are renewable sources, are under the GRAS (Generally Regarded as Safe) category, and...
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