Posted by admin on Oct 10, 2024 in |
Mosquitoes are the major deadliest insects in the world which cause the number of vectors borne diseases (e.g., Dengue, malaria, Zika virus fever, yellow fever, west Nile fever, Japanese encephalitis) in human being. In present years, interest in plant-based products has been revived because of the development of resistance, cross-resistance and possible toxicity hazards associated with synthetic insecticides and their rising costs. Presently available mosquito repellent in the market is based on the chemical and they aretoxic against the skin and nervous system, thereby they cause skin rashes, swelling, eye irritation, and other health problems. So, to overcome these herbal products are more preferred than chemical-based mosquito repellents. Herbal materials belonging to different plant species and their mixtures have been seen to act as effective repellent against various mosquitoes and pests. The easy availability and less adverse environmental impact have led to the increased interest in plant origin repellants which are safe and biodegradable alternatives to synthetic chemical repellants for use against mosquitoes and pests. The easy availability and...
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Posted by admin on Oct 10, 2024 in |
Dietary health supplements have been increasingly utilized in the prevention and treatment of chronic disorders. Over the past few decades, fenugreek (Trigonella foenum-graecum) seeds have been reported to exhibit hypoglycemic and cholesterol-lowering effects in both type 1 and type 2 diabetes mellitus patients, as well as in experimental diabetic animal models. The aim of this paper is to review the research findings on the use of fenugreek in diabetes management. There is compelling research evidence indicating that fenugreek can improve hyperglycemia and offer protection against diabetic complications through its immunomodulatory, insulin-stimulating, and antioxidant effects, as well as by enhancing adipocyte differentiation, reducing inflammation in adipose tissues, and preventing or mitigating pancreatic and renal damage. Many of the beneficial effects of fenugreek in diabetes have been attributed to four key bioactive components: diosgenin, 4-hydroxyisoleucine, furostanolic saponins, and its fiber...
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Posted by admin on Oct 10, 2024 in |
Chronic diabetic wounds are a common complication in individuals with diabetes and can lead to severe health issues if not treated quickly. Due to its capacity to improve cellular energy metabolism, Creatine monohydrate (CrM) has been suggested to possess potential health benefits. The effectiveness of a topical CrM formulation in healing chronic diabetic wounds in male Wistar rats was investigated in this research along with placebo, marketed formulation. Over the course of 21 days, the reduction of the wound and its fast pace of healing were observed. In contrast to the disease control group, the treatment group lesion size was significantly reduced and its wound closure rate was significantly higher. Increased collagen deposition and angiogenesis were also found by histological analysis in the CrM group, suggesting improved tissue regeneration. In conclusion, the topical CrM formulation showed encouraging benefits on wound healing and may have application in the therapeutic management of chronic diabetic...
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Posted by admin on Oct 10, 2024 in |
Artocarpus heterophyllus Lam, popularly known as Ceylon jack tree or jackfruit, evergreen tree reaching 8-25 m high, belongs to the family Moraceae. The trunk is straight, rarely buttressed, with a circumference of 50-100 cm. The stems are straight, forming a 30° angle with the trunk. The leaves are alternate, simple, pinnately veined, coriaceous, glossy, 4-25 cm long x 2-12 cm, dark green on the upper side and pale green beneath. The leaf has many therapeutic properties especially its diabetes control, antioxidant and anti-aging properties. Traditionally leaves are useful in fever, boils, wounds and skin diseases. In the present study, we discuss and highlight the recent findings concerning the different classes of RA therapies including the conventional and modern drug therapies. Approximately, one per cent of the world population lives with rheumatoid arthritis (RA), with at least twice as many women affected as men. Selection of leaves are important as compared to the other parts because it includes more constituents and also can be cheaply...
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Posted by admin on Aug 31, 2024 in |
This study investigates the antioxidant properties and chemical composition of Linum usitatissimum L. (flaxseed) extract using High Resolution-Liquid Chromatography Mass Spectrometry (HR-LCMS) analysis. The primary objective is to identify the bioactive compounds responsible for the antioxidant activity and evaluate the efficacy of flaxseed extracts prepared with different solvents, including methanol, ethanol, acetone, chloroform, petroleum ether, and ethyl acetate. Methodologically, the study employs various antioxidant assays such as DPPH, ABTS, FRAP, and total Antioxidant Activity (TAA), in conjunction with HR-LCMS analysis for comprehensive chemical profiling. Key findings reveal that methanolic and ethanolic extracts exhibit the highest antioxidant activities, with significant amounts of phenolic and flavonoid compounds identified. The HR-LCMS analysis further elucidates the presence of metabolites such as adenosine, abscisic acid glucose ester, and kaempferol 7-O-glucoside, which contribute to the observed bioactivity. The study concludes that flaxseed extracts, particularly those obtained with methanol and ethanol, possess substantial antioxidant potential, underscoring their potential application in nutraceuticals and functional...
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