Posted by admin on Sep 30, 2025 in |
Sore throatis acute inflammation of the pharynx and/or palatine tonsils, usually caused by an infection (viral or bacterial) and which frequently leads to the inappropriate use of antibiotics. In the context of antimicrobial resistance, herbal medicines, which contain multiple bioactive compounds, may offer alternatives. Hence, this study was conducted to evaluate the clinical efficacy and tolerability of a Cymbopogon giganteus Chiov (Poaceae) essential-oil oropharyngeal spray previously characterized for in-vitro and in-vivo antimicrobial activity. Asingle-arm phase 2 clinical trial was conducted at the Suru-Léré University Hospital Center, on adult aged 18 to 65 years with physician-diagnosed uncomplicated sore throat. Participants received the oropharyngeal spray for 7 days on an outpatient basis. Clinical efficacy was assessed using the main specific clinical signs observed on days 3 and 7 with a pre-established score. A total of 39 patients were enrolled. Rapid and substantial symptom reduction was observed by day 3 and maintained on day 7, yielding a final clinical success rate of 94.4%. Adverse events were limited to mild, transient hypersalivation (n=4)...
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Posted by admin on Sep 30, 2025 in |
Background: The present study was carried out to evaluate the wound healing potential of seed extracts of Lagenaria siceraria in two different types of wound models in albino rat viz., incision and excision. The plant has been used traditionally for its cardio protective, cardio tonic, general tonic, aphrodisiac and acts as alternate purgative, diuretic. It all so cures pain, ulcers, fever, and used for pectoral cough, asthma and other bronchial disorders. The plant has been studied for their various pharmacological activities like antioxidant, cardioprotective, diuretic, hepatoprotective and anti-inflammatory activity. Methodology and Results: In the present investigation we have screened the ethanol, ethyl acetate, n-butanol and pet. ether extracts of the seeds of the plant. The plant contains various phytochemical constituents like saponin, triterpenoid, flavones, vitamin B and source of ascorbic acid in fruits. The result data compare with the standard drug povidine iodine ointment. The ethanolic extract at a dose of (250 mg/kg) possesses a significant increase in wound contraction and formation of scar in an excision wound model....
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Posted by admin on Sep 30, 2025 in |
Dracaena sanderiana, commonly known as lucky bamboo, is an ornamental plant belonging to the family Asparagaceae, with potential medicinal properties that have been acknowledged in traditional medicine. The fresh as well as dried powdered specimens of roots were subjected to basic pharmacognostic examinations like morphological, and histological evaluations, qualitative phytochemical investigations, physicochemical evaluations including moisture content determination, ash values and extractive values to unveil the pharmacognostic characteristics this ornamental plant with ethnomedical properties. Macroscopy and Microscopy of the roots plant of Dracaena sanderiana was studied and various features were identified. In the present study, the phytochemical screening of ethanolic root extract of Dracaena sanderiana showed the presence of carbohydrates, proteins, amino acids, saponin, steroids and triterpenoids, glycosides, flavonoids and showed the absence of tannins and alkaloids. Concluding with the evaluation of antibacterial activity of ethanolic root extract of Dracaena sanderiana, it is evident that further research is needed to fully understand its potential in combating bacterial infections. The findings suggest a negative activity, yet additional studies are needed to...
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Posted by admin on Sep 30, 2025 in |
Moringa oleifera is the plant most frequently used by diabetic patients in Bamako (Mali) for the management of their diabetes. The present study aimed to determine the pharmacognostic parameters of the leaves of Moringa oleifera harvested in Mali. The pharmacognostic study consisted of determining the botanical characteristics (organoleptic features and microscopic elements), physicochemical parameters (water and ash contents), and chemical constituents according to methods described in the European Pharmacopoeia. The powder of leaves of M. oleifera was green in color, with a semi-coarse texture, an uncharacteristic odor, and an insipid flavor. Micrograph revealed the presence of anomocytic stomata, calcium crystals, single-celled covering hairs and spiral vessels. The water content is greater than 10%. The contents of insoluble ashes in 10% diluted HCl were less than 1%. Phytochemical screening revealed the presence of polyphenols (flavonoids and tannins), saponins, sterols and triterpenes. Pharmacognostic parameter determined on this study can help in the efficient utilization of this medicinal...
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Posted by admin on Sep 30, 2025 in |
`Yastimadhuvati’ is a popular Ayurvedic formulation prescribed in cough, cold, respiratory diseases and chronic fever. The proposed study is aimed at developing physico-chemical parameters and estimating the contents of glycyrrhetinic acid and piperine in the formulation. Pills were prepared according to the Vaidyaka chikitsasar. The pills were subjected to pharmacognostical and phytochemical screening and evaluated for the standards visually, weight variation, friability and hardness tests. Further glycyrrhetinic acid was quantified by colorimetric method. Also a simultaneous HPTLC method was developed for quantification of glycyrrhetinic acid and piperine. The pills showed microscopical features like sclereids, crystal fibres, vittae, epidermis with subepidermis and oil glands. The acid insoluble ash was found to be 0.5 ± 0.61, Water soluble extractive value was higher than the alcohol soluble extractive value. The pills contained higher amounts of phenolics. The content of glycyrrhetinic acid was found to be almost same (0.4% w/w) when estimated by colorimetric and HPTLC methods. Piperine content was found to be 3.5%w/w using the same HPTLC method. The quality parameters developed...
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