Posted by admin on Jan 30, 2026 in |
The rising demand for natural and skin-friendly personal care products has prompted the exploration of plant-based formulations. This study focuses on the development and evaluation of an organic herbal cleanser incorporating Spinacia oleracea (spinach) and Murraya koenigii (curry leaf) extracts, known for their antioxidant, anti-inflammatory, and antimicrobial properties. Two gel-based formulations were prepared using Carbopol 934 as a gelling agent, glycerine as a humectant, and sodium lauryl sulfate as a foaming agent. Formulations were evaluated for physical characteristics, pH, spread ability, washability, and foamability. Both formulations exhibited pale green color, smooth consistency, pleasant herbaceous aroma, and easy washability. Among the two, formulation F2 demonstrated superior gel formation, optimal pH (5.2), excellent spreadability, and stable foam. Preliminary phytochemical analysis confirmed the presence of flavonoids, alkaloids, tannins, steroids, and glycosides in the extracts, supporting their bioactive potential. The results suggest that the developed herbal cleanser is safe, effective, and cosmetically acceptable for routine facial care. This eco-friendly, plant-powered formulation offers a promising alternative to synthetic cleansers, aligning with the growing trend...
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Posted by admin on Jan 30, 2026 in |
The aqueous leaf extract of Corchorus olitorius Linn. (Family, Tiliaceae) and Carica papaya Linn. (Family, Caricaceae) was screened for in-vitro anthelmintic activity against earthworms (Pheretima posthuma) by brine shrimp lethality bioassay. The extract showed anthelmintic activity at all the concentrations of 100mg/ml, 50mg/ml and 25mg/ml. However, at a dosage of 100 mg/ml, strong anthelmintic action was identified. The time needed for earthworms to become paralyzed and death at this concentration was Corchorus olitorius Linn. about 80 and 120 minutes (conc. 100mg/ml) and Carica papaya Linn. about 74 and 90 minutes(Conc. 100mg/ml) whereas time taken for paralysis and death by the standard drug Albendazole at 50mg/ml was about 180 and 203 minutes respectively. The experimental results suggest that Corchorus olitorius Linn. and Carica papaya Linn. has in-vitro anthelmintic...
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Posted by admin on Jan 30, 2026 in |
Indonesia is one of the largest agricultural countries in the world. In 2022, approximately 88.89% of the workforce was employed in the agricultural sector. One of the most important agricultural practices is the use of pesticides, which are essential for pest control. Organophosphates are widely used pesticides, and chlorpyrifos is one of the most commonly applied organophosphate insecticides. However, chlorpyrifos exposure may cause adverse health effects, including poisoning, organ damage, mortality, and insulin resistance. Butyrylcholinesterase (BChE) activity and serum glucose levels are important biomarkers for evaluating chlorpyrifos toxicity, as exposure to chlorpyrifos can decrease BChE activity and increase serum glucose levels. Chlorpyrifos is available in two forms, analytical standard chlorpyrifos (Pestanal) and trademark formulations such as Dursban 200 EC. However, studies comparing the effects of trademark and analytical standard chlorpyrifos on BChE and serum glucose levels are still limited. This study aimed to compare BChE activity and serum glucose levels between control and treatment groups, as well as between Pestanal and Dursban treatments. Rats were orally administered Pestanal or...
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Posted by admin on Jan 30, 2026 in |
The genus Impatiens encompasses a diverse array of species valuable as sourcs of natural medicine some of which remain unexplored and insufficiently characterized. Impatiuens is a reservoir of metabolites such as phenolics, phytosterols, triterpenoids, and peptides which exhibit spectrum of activities including antimicrobial, cytotoxic, anti-inflammatory, antioxidant and anti-anaphylactic. Impatiens walleriana belonging to the family balsaminaceae is known for its aesthetic appeal and as folk medicine. Drug resistant strains of Candida and Aspergillus have made fungal infection treatment difficult and plants are serving as good alternatives. Impatiens walleriana is anti-microbial and traditionally applied to skin in folk medicine but has not been specifically screened for its anti-Candida albicans effectiveness hence, the present in-vitro study. The hydroalcoholic extract of the aeria parts of Impatiens walleriana has shown anti-Candida albicans effect with MIC 3.3mg/ml and ZOI ranging from 9mm to 20mm with maximum effectiveness at 100mg concentration in the triplicate readings taken for the selected doses 50mg, 100mg and...
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Posted by admin on Nov 30, 2025 in |
Latex-bearing plants represent a rich source of bioactive compounds with significant medicinal value with wound healing property, antimicrobial activity, antiinflammatory and anticancer activity. The present investigation was aimed at evaluating the antioxidant activity, protease characterization and antimicrobial activity of latex extracts of Plumeria alba, Euphorbia grantii and Calotropis gigantea. Phytochemical analysis revealed that Calotropis gigantea latex contained the highest phenolic content, while Plumeria alba showed maximum protein and carbohydrate content. Antioxidant assays such as DPPH radical scavenging, reducing power assay and lipid peroxidation inhibition demonstrated strong antioxidant activity, particularly in Calotropis gigantea latex. Antimicrobial screening against Staphylococcus aureus using agar well diffusion method showed the highest zone of inhibition for Calotropis gigantea. Protease activity was maximum for Euphorbia grantii with optimal pH 8, with temperature optima of 40°C for Plumeria alba and Euphorbia grantii and 60°C for Calotropis gigantea. These findings support the traditional medicinal use of plant latex and suggest its potential application in pharmaceutical and industrial...
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