Posted by admin on Mar 31, 2025 in |
This review explores the phytochemistry and pharmacological activities of Hedera nepalensis, commonly known as Chinese or Himalayan ivy. It contains various beneficial compounds such as saponins, phenolics, polyacetylenes, and essential oil. H. nepalensis shows strong antioxidant effects, fights bacteria, fungi, viruses (like influenza A and SARS-CoV-2), and even has anti-cancer properties. It helps reduce blood sugar levels and is used for diabetes management by blocking an enzyme called DPP-4. The plant also protects the liver, helps wounds to heal faster, and is effective against parasites. H. nepalensis is used to treat respiratory problems, joint pain, infections, and skin conditions in traditional medicine. Modern studies confirm these traditional uses and reveal new possibilities for its compounds to be used in medicines. In conclusion, H. nepalensis is a valuable plant with a wide range of health benefits. More research is needed to fully understand its potential, improve extraction methods, and develop safe, effective medicines from...
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Posted by admin on Mar 31, 2025 in |
Cissus quadrangularis Linn (CQ), a perennial medicinal herb of the Vitaceae family, has gained significant attention due to its extensive pharmacological and therapeutic properties. Commonly referred to as “Hadjod” or “Bone Setter,” it is widely used in traditional medicine systems such as Ayurveda, Unani, and Siddha for its bone-healing, anti-inflammatory, and antimicrobial benefits. The plant’s bioactive compounds include flavonoids, triterpenoids, stilbenes, phytosterols, calcium oxalate, and essential vitamins, which contribute to its pharmacological versatility. CQ exhibits diverse therapeutic activities, including anti-ulcer, antioxidant, anti-inflammatory, hepatoprotective, gastroprotective, antiosteoporotic, and antimicrobial properties. Its ability to enhance bone regeneration and mineralization has been widely studied, particularly in the context of osteoporosis and fracture healing. In addition, the plant demonstrates free radical scavenging, antibacterial, anti-hemorrhoidal, and hepatoprotective effects through its bioactive phytoconstituents. Its extracts show efficacy against various pathogens, promote gastrointestinal health, and have potential applications in managing oxidative stress-related disorders. This review provides an in-depth overview of the botanical, chemical, and pharmacological attributes of Cissus quadrangularis Linn, emphasizing its traditional uses and modern therapeutic...
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Posted by admin on Mar 31, 2025 in |
Traditionally Mallotus philippinensis Lam. Mull. Arg (Euphorbiaceae) has been reported to treat a variety of ailments, particularly skin conditions and wounds. The objective of the current work is to formulate and optimize the emulgel formulation containing Mallotus philippinensis (MP) Lam. Muell. Arg extract. Moreover, it seeks to validate the traditional claim by investigating the effects of topical emulgel on diabetic wound healing. Initially extract of Mallotus philippinensis Lam. Mull. Arg fruit was prepared using 70 % ethanol. The extract was evaluated for antimicrobial and antioxidant activity. The formulations (F1 to F6) incorporating varying concentrations of extract were prepared and Carbopol 934 used as a gelling agent. The formulations were assessed for rheological, physicochemical properties, drug release, stability and healing of diabetic wounds. Wound healing potential was assessed using an excision wound model in streptozotocin induced diabetic rats. The optimized formulation F6 demonstrated satisfactory drug release and prominent diabetic wound healing activity in comparison to other formulations. Hence, emulgel infused with ethanolic fruit extract of Mallotus philippinensis Lam. Mull. Arg...
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Posted by admin on Feb 28, 2025 in |
Vernonia cinerea is a plant with traditional uses in various cultures for its medicinal properties. It has been used to treat digestive disorders, respiratory infections and skin conditions. Scientific studies have shown that, it possesses antioxidant, antimicrobial, and anti-inflammatory properties, making it a promising candidate for the development of new drugs or natural remedies. A comprehensive literature review indicates that terpenoids, particularly sesquiterpene lactones, are the predominant secondary compounds found in V. cinerea. Various terpenoids, including C11-terpene lactone, megastigmane, and triterpenes, have been identified. Additionally, steroids, flavonoids, phenolic compounds. Studies have revealed that Vernonia cinerea possesses potent antioxidant, antimicrobial, antifungal, analgesic, antipyretic and anti-inflammatory properties. Overall, the future of Vernonia cinerea in the field of medicine appears bright, and further research efforts should be directed towards unlocking its full therapeutic potential. So, it is time to appreciate this plant and use it to its full potential. However, in-depth studies are needed on the clinical use of Vernonia cinerea against human diseases. Besides, detailed toxicological analysis is also to be...
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Posted by admin on Feb 28, 2025 in |
Hemigraphis hirta, a member of the Acanthaceae family, is locally known as buripana and borati gas and widely considered a medicinal plant in its native Bangladesh. It has been utilized for treating abdominal pain, glossitis, stomatitis, acute wounds, and helmintic infections. Analgesic activity was studied in rats using acetic acid induced writhing method. Diclofenac sodium25 mg/kg and vehicle served as standard and control respectively. Two doses 200 mg/kg and 400 mg/kg of plant extract exhibited significant (P<0.05) analgesic activity in acetic acid induced writhing method in comparison to control.CNS depressant activity was studied in mice by open field and hole cross methods respectively. In both models, the standard drug used was Dizepam2 mg/kg. The two doses of plant extract exhibited significant CNS depressant activity in open field (P<0.05) and hole cross tests in comparison to control. In conclusion H. hirta possesses analgesic and CNS depressant...
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