A SYSTEMATIC ETHNOPHARMACOLOGICAL REVIEW ON VERNONIA CINEREA (L) LESS

Vernonia cinerea is a plant with traditional uses in various cultures for its medicinal properties. It has been used to treat digestive disorders, respiratory infections and skin conditions. Scientific studies have shown that, it possesses antioxidant, antimicrobial, and anti-inflammatory properties, making it a promising candidate for the development of new drugs or natural remedies. A comprehensive literature review indicates that terpenoids, particularly sesquiterpene lactones, are the predominant secondary compounds found in V. cinerea. Various terpenoids, including C11-terpene lactone, megastigmane, and triterpenes, have been identified. Additionally, steroids, flavonoids, phenolic compounds. Studies have revealed that Vernonia cinerea possesses potent antioxidant, antimicrobial, antifungal, analgesic, antipyretic and anti-inflammatory properties. Overall, the future of Vernonia cinerea in the field of medicine appears bright, and further research efforts should be directed towards unlocking its full therapeutic potential. So, it is time to appreciate this plant and use it to its full potential. However, in-depth studies are needed on the clinical use of Vernonia cinerea against human diseases. Besides, detailed toxicological analysis is also to be performed for its safe and efficacious use in preclinical and clinical studies as a health-promotions herb account of pharmacognostical and phytochemical updated profile.