Posted by admin on Jan 1, 2014 in |
Kidney stone is one of the most prevalent disease worldwide calcium oxalate has been shown to be the main components of the majority of stones formed in the urinary system of patients with urolithiasis. The main objective is to study the inhibition effect of coleus Aromaticu benth. On the calcium oxalate crystal. The antilithiatic activity of Coleus Aromaticus was investigated on nucleation growth of calcium oxalate crystal. The effect of the extract on antilithiatic activity formed by Turbidity method at 620nm by mean of the spectrophotometer. The methanol extract of Coleus Aromaticus as shown significant activity on comparison to synthetic drug Cystone and Neeri. The maximum Percentage inhibition of calcium oxalate nucleation was found 62.48% in methanol extract. We concluded that the Methanol extract of Coleus Aromaticus Benth. act on nucleation crystal...
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Posted by admin on Jan 1, 2014 in |
Emergence of new strains of Escherichia coli with the ability of resistance to a wide range of antibiotics necessitates the efforts to search alternatives for better treatments to deal with these infections. Chamomile is one of the most widely used herbs in the world. In this study, we investigated the potential therapeutic effects of chamomile chloroform extract on E. coli intraperitoneal (IP) infection of BALB/c mice. Female BALB/c with an average weight of 20 to 25 g, were divided into 8 groups. The lethal dose of the E. coli for mice has injected IP in test groups and treated with 5.25, 10.5 and 21 mg/mL of chamomile chloroform extract. The combined effect of the extract (50 µg/mg) with amikacin and amikacin alone were also examined. The highest number of survived mice at the dose of 10.5 mg/mL of extract and the highest death rate with 5.25 mg/mL of extract was observed. In the amikacin group, all infected animals were survived. The mortality rate in chamomile extract combination with amikacin...
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Posted by admin on Jan 1, 2014 in |
Diabetes mellitus is characterized by elevated plasma glucose concentrations resulting from insufficient insulin. A comprehensive herbal drug therapeutic regimen offers time tested safe and effective support to conventional therapy in the management of diabetes. This is a combination with adequate dietary management, and physical activity would provide an integrated approach to the management of this deadly disease, particularly Type 2 diabetes. In this paper, an attempt has been made to give an overview of certain Indian plants with their phytoconstituents and mechanism of action which have been studied for their antidiabetic activity. The present work offers a review addressing the detailed phytochemistry of different plants contains this...
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Posted by admin on Jan 1, 2014 in |
Calotropis gigantea (Asclepiadaceae) is a perennial herb with a long history of use in traditional medicines. A wide range of chemical compounds including cardiac glycosides, flavonoids, terpenoids, alkaloids, tannins, & resins has been isolated from this plant. The plant has been used for various disease condition including leprosy, ulcers, tumors and piles. Various pharmacological activities reported like analgesic activity, antipyretic activity, pregnancy interceptive activity, CNS activity, anti-inflammatory activity, procoagulant activity, anti-diarrhoeal activity, free radical scavenging activity, antimicrobial activity, anti-tumor activity, antifungal activity, antitussive activity, and antifeedant...
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Posted by admin on Nov 1, 2013 in |
Vitiligo is an acquired idiopathic epidermal pigment loss occurring on the body. The prevalence of the disease is less than 0.5%. Pathogenesis of vitiligo has been intriguing researchers for decades. Basic defect in vitiligo is the disappearance of melanocytes. Several therapies are prescribed for the disease; the most effective one is narrowband UVB phototherapy. Several evidence-based hypotheses have been proposed to explain the loss of melanocytes in the epidermis. Oxidative stress has been speculated to play a pivotal role in disease pathogenesis. The present study was planned to determine the effect of oral antioxidant supplementation for 4 weeks in patients undergoing Narrow Band UVB phototherapy and comparison with patients receiving Narrow Band UVB phototherapy only. 30 Vitiligo patients were recruited for the study from OPD of Department of Dermatology, Era’s Lucknow Medical College & Hospital, Lucknow. Blood was investigated for anti-oxidant parameters such as Superoxide dismutase (SOD), Catalase (CAT), Glutathione peroxidase (GPx) and Lipid peroxides (LPO). After 4 weeks oral anti-oxidant supplementation, we observed significant (p<0.05) increase in CAT,...
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