Posted by admin on Jun 30, 2018 in |
Curcuma albiflora Thw. is an important anti-inflammatory medicinal plant, which is used in Sri Lankan Traditional Medicine. The plant is endemic to Sri Lanka and unexplored. Therefore it is necessary to conduct a proper systematic study to establish a chemical profile of C. albiflora. Therefore, the current study was conducted GC-MS study on various extracts of C. albiflora. The whole plant parts of the plant C. albiflora were collected from June to October in the flowering season at Sabaragamuwa province, Sri Lanka. Samples were authenticated by National Herbarium, Peradeniya. Hydro-distillation by Clevenger’s apparatus and continuous extraction by Soxhlet apparatus were carried out on various solvents (petroleum ether, acetone, and methanol). GC-MS analyses were performed on various extracts (water, petroleum ether, acetone, and methanol) of C. albiflora. Retention index was calculated of each compound based on standard alkane chromatogram. The whole plant of C. albiflora essential oil consisted mainly of α-pinene (14.51%), caryophyllene oxide (9.35%), alcanfor (5.12%), aromadendrene oxide-I (4.81%), α-famesene (4.01%) and camphene (3.64%). While petroleum ether extract of...
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Posted by admin on Jun 30, 2018 in |
Honey is commonly used by the indigenous population in Brazil due to its large variety of physiological properties such as ulcers and dermatitis healing. The goal of this paper is to select and to test different types of Brazilian honey to be used associated with Aloe vera as an accessible wound treatment. Three types of honey were analyzed: two produced by Tetragonisca angustula in different regions of Brazil and one honey produced by Apis mellifera scutellata, associated with both water and Aloe vera. Quantitative assays, where bacterial growth curve was analyzed by optical density, were performed to test the antimicrobial activity of the samples. From the results obtained, we observed that the three types of honey studied presented a satisfactory antimicrobial activity. The association between honey and Aloe vera, besides demonstrating better antimicrobial action than each compound itself, it demonstrated better effectiveness against Enterobacteriaceae species (E. coli and S....
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Posted by admin on Jun 30, 2018 in |
Portulaca quadrifida Linn. (Portulacaceae) is commonly known as a chicken weed in English. In the traditional system, it is used to treat rheumatism and gynecological diseases, urinary tract infections, worm diseases, dysentery and dermatitis. To assess the cytotoxic potential of hydroalcoholic extract of P. quadrifida leaves using brine shrimp assay. Potassium dichromate was considered a standard reference drug. The concentrations of 10, 100, 1000 μg/ml were used in the experiment. The mature shrimps were taken, and it was treated with the extract and the standard in the respective concentrations. LC50 value was calculated for both standard and extract, and the probit analysis was made by using SPSS software. From the probit analysis, the cytotoxicity of the extract was determined by comparing it with the standard. The graph was plotted for both the standard and the extract; the extract was found to be non-...
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Posted by admin on Jul 11, 2017 in |
Standardization is the need of the hour in Ayurvedic system of medicine. The traditional systems of medicine are really effective but the problem with them is they lack in quality assurance. This enables us to recognise the quality of the formulation. The Central Council of Research in Ayurveda and Siddha has prescribed the preliminary guidelines for testing the quality of these formulations. It is essential to derive a protocol or develop methods for evaluation of herbal formulation to maintain uniformity between batches during production. The present work aims to standardize a poly-herbal churna called Gandharva haritaki Churna available in the market. The churna was procured and standardised for the parameters like organoleptic characters, physical characters, physiochemical properties and phytochemical screening etc. These parameters can determine the quality of the product. The results were found to be within the...
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Posted by admin on Jul 11, 2017 in |
The present study was investigated to establish the diuretic and antiurolithiatic activities of chloroform and ethanolic leaf extract of Melochia corchorifolia. The chloroform and ethanolic leaf extract were administered to experimental rats orally at a dose of 200 mg/ kg and 400 mg/kg. Furosemide (5 mg/kg) was used as reference standard for diuretic activity. The parameters measured for diuretic activity was total urine volume; urine electrolyte concentrations such as sodium, potassium, chloride, and bicarbonates. In the in-vitro antiurolithiatic activity, Calcium oxalate crystallization was induced by the addition of 0.01M sodium oxalate solutions in synthetic urine. The effect of chloroform and ethanolic leaf extract of Melochia corchorifolia (100, 200 and 500 μg/ml) was studied by time course measurement of absorbance at 620 nm for ten minutes using a spectrophotometer. Both the extracts show good in-vitro antiurolithiatic activity. In the in-vivo antiurolithiatic activity, urolithiasis was induced in male rats by administering ethylene glycol (0.75% v/v) in drinking water for 28 days, and the parameters such as oxalate, calcium, and phosphate were...
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