Posted by admin on Mar 1, 2014 in |
Tea is composed of many compounds. These components have various effects depending upon the amount of tea ingested and the quality of the tea apart from that green tea having various useful properties which are helpful for the human body. The present communication describes about the about the “the comparative data between various brands of tea powders and green tea by using U.V. Spectrophotometer and TLC procedure for the estimation of caffeine content in commercial available tea samples and comparative data of caffeine content along with analysis of different brands of tea samples by comparing with the green tea powder. The present methods show a detailed description of the difference between commercial brands of tea powders and green tea. A possible explanation to account for the variability in green Tea and analysis of different samples is...
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Posted by admin on Mar 1, 2014 in |
Cassia fistula Linn. (Family Leguminosae, Subfamily Caesalpinia), a very common Indian plant is known for its medicinal properties. This plant is also known as Indian Laburnum, Yellow shower because of its characteristic yellow flowers in pendulous raceme and with typical branches. It is a native of Tropical Asia. It is widely cultivated in South Africa, Mexico, East Africa, and Brazil. This plant is used in folk medicine for tumors of the abdomen, glands, liver and throat cancer. It is also used to cure burns, constipation, convulsions, diarrhea, dysuria, and epilepsy. Ayurvedic medicines recognize as carminative and laxative. It is also used to cure leprosy, skin diseases and syphilis. Phytochemical investigations prove its importance as an important, valuable medicinal plant. C. fistula is known to be an important source of secondary metabolites notably phenolic compounds. It is known as a rich source of tannins, flavonoids, and glycosides. Pharmacological activities include antibacterial, antidiabetic, antifertility, anti-inflammatory antioxidant, hepatoprotective, antitumor, antifungal activities. This article aims to provide a comprehensive review of morphology, traditional...
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Posted by admin on Mar 1, 2014 in |
Objective: Phytochemical and pharmacological investigation on the leaves of Mimusops elengi Linn. for wound healing and in-vivo antioxidant activity in albino mice. Material and Methods: The methanolic extract of leaves of Mimusops elengi was studied for its wound healing effect on excision wound model in mice and in-vivo antioxidant activity at the dose level using a biochemical estimation of blood serum in mice. Result: Preliminary phytochemical analysis revealed the presence of saponin, carbohydrate, glycosides, flavonoids, tannin and phenolic compounds. Mimusops elengi methanolic extract (MEME) was examined for wound healing activity in the form of ointment in excision wound model in mice. The extract ointment showed a considerable response in the above model as compared to standard drug Betadine ointment regarding wound contracting ability, wound closure time. Histological analysis was also consistent with the proposal that Mimusops elengi leaf extract exhibits significant wound healing effect. As antioxidant action has been reported to play a crucial role in the hepatoprotection in in-vivo model of antioxidant activity. It has been found that...
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Posted by admin on Mar 1, 2014 in |
Pharmaceutical preparations having high water content face the problem of microbial spoilage which affects consumer safety. Control on such problem is generally done by the addition of a specific preservative to these pharmaceutical preparations, but sometimes some physical changes and clinical hazards are observed even after the addition of preservatives. The present study aimed to evaluate and compare the effectiveness of preservatives in market samples of antacids, cough syrups, and ophthalmic solutions through a microbial challenge test. The samples of antacids, cough syrups, and ophthalmic solutions were challenged with 3 bacterial, and 2 fungal strains and results were periodically (0, 7, 14 and 28 day) investigated. The number of surviving microorganisms were determined using standard microbiological dilution pour-plate technique. More than 1 log reduction of microbial counts were observed in all samples at 7 day. Moreover, the log reduction in microbial counts was significantly increased up to 28 day. Results showed that preservatives Sorbitol, Sodium Citrate, and Benzalkonium Chloride present in antacids, cough syrups, and ophthalmic solutions respectively were...
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Posted by admin on Mar 1, 2014 in |
Rhizome of Kaempferia galanga (Family: Zingiberaceae) has been investigated for isolation of secondary metabolites and evaluation of bioactivities. Two cinnamic acid derivatives, Ethyl p-methoxycinnamate (KG-2) and 4-methoxy cinnamic acid (KG-9) have been isolated from the chloroform fraction of the methanolic extract of the rhizome of K. galanga using chromatographic analysis. Structures of these compounds were elucidated by extensive spectroscopic analysis and by comparing the data with the published one. In the carrageenan-induced paw edema test, at a dose of 400 mg/kg the methanolic extract, chloroform and n-hexane fraction showed a significant (p<0.05) inhibition of paw edema with 55.08, 48.85 and 71.88 % inhibition after a 2nd hour of the study period. In acetic- acid-induced writhing test, the chloroform and n-hexane extract at a dose of 400 mg/kg showed a significant (p<0.001) reduction in the number of writhes with38.19 and 62.31% writhing inhibition respectively. In hypoglycemic evaluation study by oral glucose tolerance test, all of the extracts at 200 mg/kg body weight inhibited the rise in blood glucose level. After...
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