Posted by admin on Mar 15, 2018 in |
This study was aimed to maximize the benefits of the use of by-products (oil cake) of olive fruits and black seeds after extraction of their fixed oils, rather than their use as animals feed or landfilling or composting. The cake of both seeds was assessed by HPLC for their main bioactive marker compounds (thymoquinone for black seed and oleuropein for olive fruit), to choose the best method for extraction, determination of phenolic contents and in vitro antioxidant activity (DPPH and reducing powers, FRAP assays). Both by-products were also assessed for their cytotoxicity against four human breast cell lines, three of them are cancerous (MCF7, MDA-MB-213, Vcr-R), and a non-cancerous one (epithelial type) but immortalized by telomerase (hTERT-HME), in addition to a human hepatoma cell line (HepG2). Also, both wastes were subjected for in-vitro CDC25s phosphatase inhibition assay on three isoforms (A-C) and for in-vivo immunomodulatory effects. In conclusion, the results of this study showed the interest of cumulating different biological approaches exploring various physiological mechanisms and showed the utility...
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Posted by admin on Mar 15, 2018 in |
Gymnema sylvestre R. Br is a valuable herb extensively used in the ayurvedic and indigenous medicinal system, belonging to the family Asclepiadaceae. It has the property of abolishing the taste of sugar and hence given name gurmar (sugar destroying). This plant has also found application in pharmaceuticals; the whole plant is rich in secondary metabolites, which impart medicinal uses to the plant. The view of phytochemistry gives scope for enhancement of the quality and quantity of the bioactive secondary metabolites occurring in the plant. The present review is an attempt to highlight the various phytochemical reports on Gymnema...
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Posted by admin on Mar 15, 2018 in |
Stroke is the sudden blockage or rupture of cerebral arteries that can lead to cerebral damage or clinical neurologic deficit. Generally, stroke is as ischemic and hemorrhagic. Ischemia caused by factors such as thrombosis, embolism, and systemic hypoperfusion. Stroke is one of the most important factors of mortality and disability worldwide. After a stroke, an increase of free radicals has the most important role in the breakdown of blood-brain and increase of cerebral edema. This study aimed to review the effect of compounds isolated from plants to reduce cerebral ischemia. Our review showed that natural compounds could exert a protective effect by reduction of oxidative stress and events related to it. We also suggest that consider special attention to natural product for the treatment of cerebral...
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Posted by admin on Apr 1, 2017 in |
The crude extract from the leaf of Canthium parviflorum Lam. in different solvents were subjected to physicochemical, fluorescence analysis, phytochemical and antimicrobial study. The microscopic analysis revealed that in C. parviflorum there is the presence of starch grains. The ash value was 5.81% in C. parviflorum. The fluorescent analysis at 366 nm of C. parviflorum powder extracted with alcohol showed orange-colored fluorescence with other it was no fluorescence. The extraction value with different solvents exhibited that C. parviflorum had maximum extractive value with chloroform followed by benzene, ethanol and petroleum ether. The phytochemical screening of the various extract of C. parviflorum revealed that the benzene extract showed the presence of alkaloids, tannins, flavonoids, saponins, and steroids. The chloroform extracts of the leaf showed the presence of alkaloids, tannins, flavonoids, saponins, and steroids. Anti-bacterial screening in C. parviflorum using stem revealed that the ethanol solvent showed maximum inhibition against gram-positive bacteria (Staphylococcus aureus) and chloroform solvent showed maximum inhibition in the case of gram-negative bacteria (Serratia...
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Posted by admin on Apr 1, 2017 in |
Sulfated polysaccharides (SP) were extracted from Corallina officinalis marine red algae seaweed by using hydrothermal processes at 100 °C. The antioxidant activity of C. officinalis sulfated polysaccharide was determined using the (2,2-diphenyl-1-picrylhydrazyl, DPPH) method, showing that this polysaccharide has a moderate effect in inhibiting the formation of those radicals. This study demonstrates that sulfated polysaccharide obtained from marine red algae have the potential for use as natural antioxidants in industrial food...
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