Posted by admin on Apr 23, 2016 in |
Protective effect of the probiotic combination of usnic acid and Lactobacillus casei in experimentally induced ulcer in rats was investigated. Rats inward usnic acid (100 mg/kg), L. casei (10-8 con.), usnic acid (100 mg/kg) + L. casei (10-8 con.), and omeprazole (30 mg/kg) twice daily for 5 days for prevention against aspirin (ASP), ethanol (EtOH), cold restraint stress (CRS) and pylorus ligation-induced ulcer (PL). The results of the present study showed the first time that the usnic acid (100 mg/kg) + L. casei (10-8 con.) as probiotic combination significantly inhibited the ulcer index in ASP, EtOH, CRS and PL to 3.4 ± 0.12, 6.3 ± 1.8, 3.4 ± 0.8 and 4.3 ± 0.9 (p<0.001) respectively, as compared to control group (19.2 ± 1.6, 22.5 ± 6.3, 24.2 ± 3.2, 14.2 ± 2.7). Besides usnic acid (100 mg/kg) + L. casei (10-8 con.) offered protection (72%, p<0.001) against ethanol-induced depletion of gastric wall mucus. The usnic acid (100 mg/kg) + L. casei (10-8 con.) showed significant inhibition of lipid peroxidation...
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Posted by admin on Apr 23, 2016 in |
Cardaria draba commonly known as whitetop or hoary cress is a perennial herb that is native to Eastern Europe and eastern Asia, including Iran. In this study, the effects of alcoholic extract of Cardaria draba (25, 50 and 100 mg/kg) via oral gavage for 2 weeks alone and on scopolamine (1 mg /kg/d, 4 days, i.p.) – zinc chloride (75 mg/kg/d, 2 weeks oral gavage) – and sodium metavanadate (22.5 mg/kg/d, 2 weeks oral gavage) – induced avoidance memory retention alterations were investigated in the step-through passive avoidance task. Zinc chloride and scopolamine were dissolved in saline and sodium metavanadate were dissolved in animal’s drinking water. At the end of each part of studies, animals were trained for one day in a step-through task. The avoidance memory retention alterations were evaluated 24 h, 48 h, 96 h and 168 h later to the training session. Zinc chloride and sodium metavanadate oral gavage for 2 weeks decreased latencies compared to control animals. Also, four days intra-peritoneal injection of scopolamine decreased...
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Posted by admin on Apr 23, 2016 in |
Moringa oleifera Lam. is the most imperative and legendary species of family Moringaceae. It is called as Soanjna in the local language (Punjabi). It has noteworthy medicinal and nutritional significance for both humans as well as for animals. Traditionally it is recommended to treat many ailments and to contest malnutrition mostly in tropics. It has scores of pharmacological activities such as anticancer, antioxidant, antispasmodics, anti-inflammatory, antimicrobial, anti-asthmatic, antidiabetic, antiarthritis, antiurolithiatic, hepatoprotective, nephro-protective, cardioprotective, antipyretic and antiulcer, etc. Its non-food benefits such as purification of water, as biodiesel oil and bio-enhancing activity are also valuable. The present review on the phytochemistry, pharmacology and nutritional strength of Moringa oleifera is an effort to give an updated literature appraisal of its...
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Posted by admin on Apr 23, 2016 in |
Sexually transmitted diseases are serious problem concerned with health, social and economic challenges in the world, especially in Africa. Rural patients are more dependent on folk medicinal healers for treatment of sexually transmitted diseases. Rural people depend on traditional medicinal plants because of lack of access to modern medical facilities and hesitancy to relate this form of illnesses in front of unknown doctors. These medicinal plants have been used for the treatment of many sexually transmitted diseases without any scientific evidence. Since, the traditional healer usually resides in the same village or an adjoining area, the patient is more comfortable in seeking them for treatment. At present, there is more emphasis on determining the scientific evidence and rationalization of the use of these preparations. Taking into account the large number and structural diversity of currently available plant constituents, the plant kingdom remains an exciting source for new antiviral and anti-bacterial...
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Posted by admin on Apr 6, 2015 in |
In the present study, an indigenous herbal formulation containing the ethanolic extracts of rhizomes of Curcuma longa, fruits of Terminalia chebula, leaves of Azadirachta indica, leaves of Lawsonia inermis and leaves of Achyranthus asperus were prepared and studied for its wound healing activity in an ointment base by using in in-vivo excision wound model in albino wistar rats. The ointment was prepared with extracts in three different concentrations, i.e., 1%, 2% and 3% (w/w) and applied on excision wound twice daily for 16 days. Povidone-iodine was used as reference standard. It was observed that the wound healing contracting ability of the polyherbal extract in ointment base in different concentrations was significantly p<0.01 superior to that of the control (i.e., simple ointment treated group). The epithelialization time in the treated group was found to be less as compared to control. The most effective concentration of the polyherbal extract in ointment base was found to be 3% (w/w) for wound...
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