Posted by admin on Mar 15, 2018 in |
Stroke is the sudden blockage or rupture of cerebral arteries that can lead to cerebral damage or clinical neurologic deficit. Generally, stroke is as ischemic and hemorrhagic. Ischemia caused by factors such as thrombosis, embolism, and systemic hypoperfusion. Stroke is one of the most important factors of mortality and disability worldwide. After a stroke, an increase of free radicals has the most important role in the breakdown of blood-brain and increase of cerebral edema. This study aimed to review the effect of compounds isolated from plants to reduce cerebral ischemia. Our review showed that natural compounds could exert a protective effect by reduction of oxidative stress and events related to it. We also suggest that consider special attention to natural product for the treatment of cerebral...
Read More
Posted by admin on Feb 5, 2018 in |
Argemone mexicana Linn. has been reported to possess antimicrobial, cytotoxic, antimalarial and other pharmacological activity. The present study was found to be alkaloids, amino acids, phenolics, and fatty acids are isolated by using different exaction methods of isolation and characterization use to determine. The present article reviews the pharmacological and phytochemical work done on the plant and determines a scientific base for novel study for future research to establish toxin free response of plant or its...
Read More
Posted by admin on Feb 5, 2018 in |
Cancer is one of the most common reasons for mortality worldwide. Leukemia as one type of cancer is a serious threat to human. Although there are many synthetic drugs to treat leukemia, but the use of them is limited due to a side effect, therefore there is a dire need to find a promising solution. Herbs and their compound can be promising candidates for control leukemia. In this study, we review new studies entitled role of extracts of herbs to inhibit leukemia from 2014 to now. Our review study showed that herbs have anticancer activities through cell proliferation inhibition. This feature is due to induction of apoptosis and increase of free radical formation in cancer cell. Finally, we suggest that need to special attention to herbs in order to treat...
Read More
Posted by admin on Jan 11, 2018 in |
Diabetes mellitus (DM) is being one of the major causes of morbidity and mortality, which seriously threatens the health of human beings. Worldwide around 366 million people are found to be affected by diabetes. DM is a chronic condition associated with abnormally high levels of sugar (glucose) in the blood. Absence or insufficient production of insulin, or an inability of the body to properly use insulin causes diabetes. DM can be classified as either type 1 or type 2. Type 1 diabetes conditions or insulin-dependent, which treated by insulin therapy. Type 2 diabetes or non-insulin-dependent, which treated by oral hypoglycemic drugs. Conventional insulin and other oral anti-diabetic agents delivery associated with many drawbacks, the need for frequent monitoring of blood glucose, multiple insulin injections, and adjustment of insulin dosages, self-injection, and difficulties in using the vial and syringe technique are among the barriers to patient compliance. Most oral anti-diabetic drugs exhibit low oral bioavailability and need frequent dosing owing to short half-lives, resulting in poor patient compliance. Therefore, to...
Read More
Posted by admin on Nov 13, 2017 in |
Calotropis gigantea Linn. white (Asclepiadaceae), it is a weed plant commonly known as giant milkweed. It has one of the important traditional medicines to treat various ailments. The basic aim of this study to Calotropis gigantea is one such plant. In this review, the systematic position, introduction about the plant, morphological study, phytochemistry and the economical values of the Calotropis gigantea are discussed. Calotropis gigantea is a glabrous or hoary, laticiferous shrubs or small trees, it also known as “the swallow-wort or milkweed.” Calotropis is used as a traditional medicinal plant. C. gigantea contains chemical constituents are cardenolides, flavonoids, terpenes, pregnanes, and nonprotein amino acid. The latex, leaves, flowers, bark, the root is also used as caustic, acrid, expectorant, depilatory, antihelmintic, useful in leprosy scabies ringworm of the scalp, piles, eruptions on the body, asthma, enlargement of spleen and liver, dropsy applied to painful joint swellings. This review gives a brief idea about its phytochemistry and pharmacological...
Read More