Posted by admin on Sep 30, 2019 in |
Curcuma aromatica salisb, which belongs to the Zingiberaceae family, is a perennial herb. The rhizome of the plant consists of alkaloids, curcuminoids, flavonoids, tannins, and terpenoids which are reported to be the reasons for its various pharmacological properties. The extraction of compounds in different solvents shows that the plant contains neocurdione, curdione and germacrone as its major components. An extensive literature survey showed that the plant has anti-obesity, anti-acne, anti-cancerous, anti-tussive, anti-oxidant, larvacidal anti-inflammatory, anti-bacterial and wound healing properties. The rhizome extract of the plant is highly effective against many human pathogens as well as microorganisms causing food spoilage and foodborne diseases. The aim of this study is to review the phytochemical and pharmacological properties of Curcuma aromatica...
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Posted by admin on Aug 31, 2019 in |
Piper betel Linn. an important species of the Piperaceae family is an evergreen and perennial creeper, with glossy heart-shaped leaves that are magnificent reservoirs of phenolic compounds with anti-proliferative, anti-mutagenic, antibacterial and antioxidant properties. Phytochemical studies show that Piper betel contains a wide variety of biologically active compounds whose concentration depends on the variety of the plant species. Many research studies on Piper betel has reported that it contains important chemical constituents such as chavibetol, chavibetol acetate, caryophyllene, allylpyrocatechol diacetate, campene, chavibetol methyl ether, eugenol, a-Pinene, f-Pinene, u-Limonene, safrole, 1-8-cineol, and allylpyrocatechol monoacetate. These components are valued as a stimulant for its medicinal properties like anti-fungal, anti-nociceptive, anti-cancer, immunomodulatory, anti-halitosis, anti-diabetic, gastroprotective, anti-allergic, anti-fertility, anti-filarial, anti-larvicidal, wound healing and anti-dermatophytic. The present review is an attempt to highlight various traditional uses as well as pharmacological reports on Piper betel...
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Posted by admin on Jul 31, 2019 in |
Tinospora cordifolia (T. col.), a plant which has great significance in the Ayurvedic system of medicine, has been tested according to modern medical techniques for numerous therapeutic effects like immunomodulation, reducing tumor cells, purification of blood, reducing fatty lipids from body, reduction of glucose and increasing glucose tolerance in case of diabetes and increasing body weight. T. col has been used even during various rheumatic diseases like rheumatoid arthritis and has shown positive therapeutic effects. T. col. reduces the unwanted lipids. It enhances the humoral immune response. It also cleans out the immune complexes from the body. T. col. acts as an adaptogen. It has been reported to both increase and decrease activities of substances in the body, so as to normalize its functionality. It enhances immunity, but on the other hand, it inhibits autoimmunity. This paper is a review of the findings of the medical benefits of T. col., and combining all the information to propose that this plant may be used in the treatment of another rheumatic...
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Posted by admin on Jul 31, 2019 in |
Ocimum tenuiflorum Linn. commonly known as holy basil, tulsi is an aromatic perennial plant in the family Lamiaceae. It is native to the Indian subcontinent and cultivated plant throughout the Southeast Asian tropics, where the leaves, seeds ad stem of tulsi are used for valuable source of culinary and traditional medicinal uses. Indian material medica describes the use of the plants in a variety of ailments such as immunostimulatory effect, gastric antiulcer activity, diabetics mellitus, hyperlipidemia, wound healing effects, protective effect, chemopreventive activity, and blood pressure, etc. The present review aims to summarize up to date information on the ethnomedicinal, phytochemical and pharmacological activity. Until now, highly complex natural molecules have identified including fixed oils, essential oils, triterpenes, flavonoids, flavonoid glycosides, polysaccharides, phenolic glycoside, lignans, and norlignans. In addition to solvent extracts, these individual active compounds have been suggested for ethano-pharmacological activities. Although the results are promising in-vitro and in-vivo preclinical studies, clinical studies are insufficient; therefore, further investigation of each active compound need to be done to validate...
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Posted by admin on May 31, 2019 in |
The role of surfactants is very critical in the development of pharmaceutical formulations. The diverse applications in different delivery systems have been highlighted in different reports of formulation development for various conventional and advanced delivery systems. The relevancy of critical micelle concentration and HLB value for the section of surfactants for different drug delivery systems was rationalized with suitable examples. The present attempt is focused on the compilation of all the important aspects of surfactants with a broad discussion on the drug delivery implications. The regulatory status of different investigational surfactants has been criticized relevantly with a compilation of FDA approved surfactants. The safety aspects of newly developed surfactants must be ensured before their incorporation in therapeutic dosage forms. The properties of different categories of surfactants were discussed with special emphasis on their physicochemical properties. The compiled information will make a firm base for the selection of surfactants for conventional and advanced drug delivery systems. Precise information on surfactant toxicity was also included to give a check to the...
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