Posted by admin on Oct 31, 2021 in |
Acacia arabica, commonly known as Babool is a multipurpose tree. AS the world is turning back towards the herbal drug, it is the need of the Hour to re-evaluate the knowledge of traditional medicine through extensive review. The use of herbal drugs to prevent and treat various health ailments has been in practice from time immemorial. Acacia arabica has been reported to be effective against a variety of diseases, including diabetes, skin disease, and, most concerning with cancer. Different parts of the plant viz., Gum, Bark, Leaves, Flowers, Seeds, and Pods, are used as medicine among various ethnic and rural societies. The study’s goal was to supply slow-release medicament for the treatment of diabetes by formulating antidiabetic compressed tablet lozenges from Acacia arabica. There is still a demand for new dosage forms that act effectively despite various other dosages such as powder, tablets, and injectables being available in the market. So the lozenges are the new and innovative way for drug delivery to provide a synergistic effect. The increased...
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Posted by admin on Oct 31, 2021 in |
Since ancient times, Hypericum species have been used in traditional therapy to treat various complaints. The plant has an important role in medicine and public health. Hypericum oblongifolium is a shrub and is mostly found in hilly areas, commonly called abheda and peoli. Literature review for various articles and journals of traditional Indian medicine revealed that H. oblong folium has a lot of medicinal properties. Leaves, flowers and stems have been reported for medicinal activity. It is traditionally determined that they had been reported for treating respiratory disease, gastric ulcer, snake bite, wound, boils, etc. The plant has also been reported for various pharmacological aspects as anti-oxidant, anti-inflammatory, anti-pyretic activity, etc. However, limited research has been performed on this plant for exploring these traditional uses. The present review explores its biological description, distribution, chemical constituents, pharmacological and traditional activities of H. oblong...
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Posted by admin on Sep 30, 2021 in |
Black pepper (Piper nigrum L.) is a widely used spice around the world. It has also been explored for its biological properties and bioactive compounds. The significance and efficacy of black pepper and its bioactive compounds in insecticidal, antiviral, antibacterial, antifungal infections are well-acknowledged throughout the world. The secondary metabolites of Piper nigrum L. are responsible for these activities. Piperine is one of the potent components in pest control due to its pungent smell. Eventually, efficient and optimal extraction methodologies are obligatory for the most competent functionalization of black pepper extract. Plausible reports are supporting its impact and application as a natural pesticide to control the pest abundance. The novel, environmentally benevolent natural pesticides are essential for pest control. In this review paper, we tried to summarize all potential, rapid, simple, feasible, and sustainable methods for black pepper extraction, isolation, and mode of action as a pest regulator. Lethal concentration, doses, and application time are the major regulating factors of a natural pesticide. Changes in the growth and developmental...
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Posted by admin on Sep 30, 2021 in |
Syzygium cumini is a smooth and famous tree, about 8 to 15 meters high with white branchlets and reddish young shoots. Leaves are opposite, shiny and leathery, oblong-ovate to elliptic or obovate-elliptic, 6 to 12 centimeters long, the tip is broad and shortly pointed. In Unani, the kernel (Khasta-e-Jamun) is used for the treatment. A lot of pharmacological work has been scientifically carried out on various parts of Syzygium cumini but some other traditionally important therapeutically uses are also remaining to proof till now scientifically. It has astringent, carminative, stomachic, diuretic, antidiabetic, anti-diarrheal, anti-inflammatory, radioprotective, gastro-protective, antioxidant, anti-allergic, anti-cancer, anti-bacterial, cardio-protective properties, etc. The various chemical constituents present in Seeds yield glycosides, a trace of pale yellow essential oil, fat, resin, albumin, chlorophyll, an alkaloid- jambosine, gallic acid, 1-galloylglucose, 3-galloylglucose, quercetin, and elements such as zinc, chromium, vanadium, potassium and...
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Posted by admin on Sep 30, 2021 in |
Indole-3-carbinol, a phytoactive constituent obtained from cruciferous vegetables like Brussels, sprouts, cabbage and cauliflower. It has chemopreventive properties supported by numerous studies carried out to prevent breast, lung, prostate, leukemia and ovarian cancer. Indole-3-carbinol possesses therapeutic benefits like antimicrobial, neuroprotective and antitumor properties. However, it has got poor oral bioavailability due to limitations like metabolic instability in acidic media, thermal instability, etc. The review focuses on the chemistry, anticancer mechanism, limitations, bioavailability, pharmacokinetics, and toxicities studies related to I3C. It also focuses on analytical methods and current approaches for developing an improved delivery system for Indole 3 carbinol by overcoming bioavailability and toxicity limitations. I3C has reported showing limited efficacy in clinical trials due to its poor oral bioavailability. Hence administration of I3C from alternative routes is explored by formulating it as nanoparticles, nanocapsules, suspensions, microemulsions,...
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