Posted by admin on Oct 1, 2014 in |
The study was carried out to assess the analgesic, anti-inflammatory, CNS depressant and anti-diarrhoeal activity of methanolic extract of Nephelium lappaceum L. seeds (MNLS). Analgesic activity was evaluated using acetic acid-induced writhing and formalin-induced licking paw test in mice. Anti-inflammatory effect was studied using the carrageenan-induced inflammatory method. Hole cross and open field models were used to evaluate CNS depressant activity whereas castor oil- induced diarrhoeal model was employed for testing anti-diarrhoeal activity. In the analgesic activity, MNLS at a dose of 500 mg/kg exhibited potent (51.27%) activity against acetic acid-induced pain in mice whereas indomethacin (10 mg/kg) displayed 58.86% inhibition. Furthermore, the extracts showed 50.87% and 57.60% inhibition of the formalin-induced paw licking in mice at a dose of 250 and 500 mg/kg b.w. respectively and indomethacin produced 70.72% inhibition. In the carrageenan-induced paw edema test, the extract showed a significant (p<0.05) inhibition of paw edema after 30 min to a 4th h of the study period. In hole cross and open field tests, maximum 88.09% and 85.94%...
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Posted by admin on Sep 1, 2014 in |
The antibacterial activity and phytochemical screening of red algae Amphiroa anceps were using three different solvents like aqueous, methanol and ethyl acetate extracts. The phytochemical screening of macroalgae showed the presence of flavonoids and terpenoids in methanol and ethyl acetate extract. The aqueous extract of Amphiroa anceps observed only tannins. The eight human pathogenic bacteria like Escherichia coli, Staphylococcus aureus, Proteus vulgaris, Klebsiella sp, Pseudomonous aeruginosa, Spreptococcus sps, Enterobacter sps and Neisseria sps used for the antibacterial activity. The highest zone of inhibition was recorded in ethyl acetate extract of the Amphiroa ance against the bacteria Enterobacter...
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Posted by admin on Sep 1, 2014 in |
Pupalia lappacea Juss belongs to the family Amaranthaceae useful in the bone fracture treatment, antimalarial, pyrexia, wounds, cough, toothache and boils. The present investigation was aimed to identify the phytocompounds by GC-MS, investigate phytochemically and to screen anti-inflammatory and antioxidant property by in-vitro methods. Bioactive compounds were identified using GC- MS; functional groups were identified using FT-IR, phytochemical estimation was done for the phenolics, flavonoids, tannins, and alkaloids, in-vitro anti-inflammatory activity by heat-induced hemolytic and albumin denaturation method, in-vitro antioxidant by DPPH, SOD, NO, PPO and CAT methods. GC-MS analysis of the methanolic extract confirmed the presence of bioactive principles like phenols, tetradecanoic acid, pentadecanoic acid, Eicosatetraenoic acid, Hexatriacontane, eicosapentaenoic acid, and chloroundecane. Methanolic extract of aerial parts of Pupalia lappacea was estimated for the presence of secondary metabolites and screened for in-vitro anti-inflammatory and antioxidant effects. Aerial parts were extracted and estimated for total phenolics 248.19 ± 4.84, flavonoids 123.47 ± 0.19, tannins 57.12 ± 2.45 and alkaloids 69.29 ± 1.84 quantitatively reaction equivalent per gram of the...
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Posted by admin on Sep 1, 2014 in |
Herbs have been widely used for centuries as remedies for diseased human conditions as they have certain phytochemicals of diseases curing nature. The present study explains the antimicrobial (antibacterial & antifungal) potential of dried stem wood of Cissuspallida methanolic extract against bacterial strains of Bacillus subtilis, Klebsiella pneumonia, Staphylococcus aureus, Escherichia coli, Pseudomonas aureginosa, and Aspergillus niger, Aspergillus fumigates, Monoscus purpure fungal strains by Disc diffusion method. The test extract was compared with Ciprofloxacin 5 μg for bacterial organisms and Fluconazole 20 μg for fungal organisms. The extract showed significant antibacterial and antifungal activity which was confirmed by the zone of inhibition...
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Posted by admin on Sep 1, 2014 in |
Peridiopsora mori (Barclay) K.V. Prasad, B.R.D. Yadav & Sullia is one of the fungi which cause brown leaf rust on Mulberry (Morus spp.). Leaf rust disease is one of the major diseases affecting Mulberry (Morus sp.). Synthetic fungicides are commonly applied to reduce disease; however, its improper use may cause residual toxicity on silkworm, environmental and health problems. The extracts of angiosperm medicinal plants were proven by previous workers to possess antimicrobial activities against plant pathogenic fungi. In this study, the antifungal activity of leaf extracts of 5 rarely occurring medicinal plants in Kerala (Mesua ferrea L., Memecylon randerianum S. M. Almeida & M. R. Almeida, Pittosporum tetraspermum Wight & Arn., Symplocos cochinchinensis (Lour.) S. Moor and Syzygium laetum (Buch.-Ham.) Gandhi) were tested against Peridiopsora mori. Antifungal activity of the leaf extract was tested based on the poisoned food technique on potato dextrose agar (PDA). Leaf extracts, 5%, 10%, 15%, 20% and 25% were tested in this study. The results of this study showed that leaf extract of all...
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